You should not use this medicine if you are allergic to atropine. You should not use the ointment form of this medicine if you have glaucoma.

To make sure ISOPTO ATROPINE is safe for you, tell your doctor if you have:

• high blood pressure;
• glaucoma.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

ISOPTO ATROPINE can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Do not give this medicine to a child younger than 3 months old.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when atropine is used in the eyes, side effects can occur if the medicine is absorbed into your bloodstream.

Children can absorb larger amounts of the medicine and may be more likely to have side effects.

Call a doctor at once if the person using ISOPTO ATROPINE has:

• severe burning or stinging of the eyes;
• severe eye redness or irritation;
• fast heart rate, restlessness or irritability;
• flushing (warmth, redness, or tingly feeling); or
• increased blood pressure--severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety.

This medicine will cause blurred vision that could last up to 2 weeks. This may impair your reactions while driving or doing anything that requires you to be able to see clearly.

Common side effects may include:

• mild stinging or pain when the drops are placed into your eye;
• mild eye pain;
• dry mouth, nose, or throat;
• puffy or watery eyes;
• blurred vision; or
• your eyes may be more sensitive to light.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Do not use atropine eye drops while wearing contact lenses. The medicine may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using the eye drops before putting in your contact lenses.

ISOPTO ATROPINE may make your eyes more sensitive to light. Wear sunglasses to protect your eyes whenever you are outdoors or in bright light.

Do not use other eye medications unless your doctor tells you to.

Tell your doctor about all your current medicines and any you start or stop using, especially:

• an MAO inhibitor--isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Although it is not likely that other drugs you take orally or inject will have an effect on atropine used in the eyes, many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Wash your hands before using eye medication.

To apply the eye drops:

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
• Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.
• Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.
• Wait at least 10 minutes before using any other eye drops your doctor has prescribed.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

To apply the ointment:

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the ointment tube with the tip pointing toward this pocket. Look up and away from the tip.
• Squeeze out a ribbon of ointment into the lower eyelid pocket without touching the tip of the tube to your eye. Blink your eye gently and then keep it closed for 1 or 2 minutes.
• Use a tissue to wipe excess ointment from your eyelashes.
• After opening your eyes, you may have blurred vision for a short time. Avoid driving or doing anything that requires you to be able to see clearly.

Do not touch the tip of the eye dropper or ointment tube or place it directly on your eye. A contaminated dropper or tube tip can infect your eye, which could lead to serious vision problems.

Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle or tube tightly closed when not in use.

Seek emergency medical attention or call the Poison Help line if you have used too much ISOPTO ATROPINE, or if anyone has accidentally swallowed the medication.

Apply the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of this medication.

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take this medicine with a full glass of water.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Store at room temperature away from moisture and heat.

Seek emergency medical attention or call the Poison Help line.

Overdose symptoms may include extreme drowsiness, nausea, vomiting, feeling like you might pass out.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using ATARAX and call your doctor at once if you have a serious side effect such as:

• restless muscle movements in your eyes, tongue, jaw, or neck;
• tremor (uncontrolled shaking);
• confusion; or
• seizure (convulsions).

Less serious side effects may include:

• dizziness, drowsiness;
• blurred vision, dry mouth; or

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You should not use this medication if you are allergic to ATARAX, or if you are pregnant.

Before you take ATARAX, tell your doctor if you have a seizure disorder, liver disease, or kidney disease.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Stop using ATARAX and call your doctor at once if you have a serious side effect such as tremors, confusion, seizures, or restless muscle movements in your eyes, tongue, jaw, or neck.

Drinking alcohol can increase certain side effects of ATARAX.

You should not use this medication if you are allergic to ATARAX, or if you are pregnant.

To make sure you can safely take ATARAX, tell your doctor if you have any of these other conditions:

• epilepsy or other seizure disorder;
• asthma, emphysema, or other breathing problem;
• glaucoma;
• heart disease or high blood pressure;
• stomach ulcer, blockage in your stomach or intestines;
• thyroid disorder;
• enlarged prostate or problems with urination;
• liver disease; or
• kidney disease.

Do not use ATARAX without telling your doctor if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether ATARAX passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more likely to have side effects from this medication.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Drinking alcohol can increase certain side effects of ATARAX.

Before using ATARAX, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by ATARAX.

This list is not complete and other drugs may interact with ATARAX. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

This medicine comes with a Patient Information Leaflet. Read it carefully for instructions on how to use this product. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine.

Clean and dry the skin before applying the patch. Peel away the protective liner and place the disc on the procedure site, usually 1 hour before the procedure or as directed by your doctor. Do not touch the white round part that contains the medication. Firmly press down on the edges of the patch to make sure it is well attached. Gently press on the center of the patch. Using a ballpoint pen, mark on the patch the time it was placed.

Remove the patch and clean the area thoroughly, usually shortly before the procedure or as directed by your doctor. The length of time for the medication to stay on the skin depends on your age and the type of procedure you are having. Do not leave it in place for longer than directed since the chance for side effects may be increased. Carefully fold the patch in half with the sticky sides together and discard out of reach of children and pets. Do not re-use the patch. Wash hands immediately after use unless you are treating an area on the hands.

This patch may be harmful if placed in the mouth or swallowed. If you are applying this product on a child, make sure the patch stays in place and that your child does not put the patch in his/her mouth. You may want to use a second covering to prevent the child from touching the patch.

Use this medication only on normal, intact skin. Do not use on open wounds/cuts/scrapes/burns/rashes (including diaper rash) or mucous membranes. Do not use this product in the ears or near the eyes. Avoid getting the product in your eyes, nose, ears, or mouth. If this medication gets in the eyes, rinse the affected eye right away and completely with water or saline. Numbness in the eye can lead to injury because you cannot feel particles in the eye or other dangers. Therefore, protect the eye until feeling returns.

The numbing effect should start within 1 hour. The area may be numb for several hours after removing the patch. Protect the area from injury. Be careful not to bump, rub, or scratch the area or expose it to heat/cold until feeling returns.

Before using this product, tell your doctor or pharmacist if you are allergic to lidocaine or prilocaine; or to any other amide anesthetics (e.g., bupivacaine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain blood disorder (methemoglobinemia), an infant younger than 1 year who is being treated with medication that can cause methemoglobinemia (see Drug Interactions section).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain blood disorder (G6PD deficiency, especially in children), heart disease (e.g., irregular heartbeat), kidney disease, liver disease, skin problems (e.g., infection, dermatitis, eczema).

If you are going to have an MRI test, tell testing personnel that you are using this patch. Some patches may contain metals that can cause serious burns during an MRI. Ask your doctor whether you will need to remove your patch before the test and apply a new patch afterward, and how to do so properly.

Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug, especially dizziness.

Caution is advised when using this drug in children, especially if your child is younger than 3 months or small for their age. These children are at greater risk for a certain rare blood problem (methemoglobinemia). Contact the doctor right away in the unlikely event your child has symptoms such as pale/bluish skin around the mouth/lips or fast heartbeat. The risk for serious side effects (including methemoglobinemia) is increased if this medication is applied for too long or too often or if too many patches are used in young children.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

Lidocaine passes into breast milk. It is unknown if prilocaine passes into breast milk. Consult your doctor before breast-feeding.

Redness, swelling, tingling, burning, or lightening of the skin may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you develop: blistering of the skin where the patch is applied.

Remove the patch and get medical help right away if any of these rare but very serious side effects occur: slow/shallow breathing, pale/bluish skin around the mouth/lips/fingernails, dizziness, fainting, fast/slow/irregular heartbeat, mental/mood changes (such as confusion, nervousness), seizure, severe drowsiness.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: drugs that may rarely cause a certain blood disorder called methemoglobinemia (e.g., acetaminophen, benzocaine, phenobarbital, antimalarials such as chloroquine/primaquine/quinine, nitrates such as nitroglycerin, certain antibiotics such as sulfonamides/nitrofurantoin/dapsone).

Serious Warnings and Precautions

EMLA Cream is for use on healthy, unbroken skin. Do not apply to open wounds, nor to burns or rashes or other skin conditions, including diaper rash.

BEFORE you use EMLA Cream talk to your doctor or pharmacist if:

• you/your child have glucose-6-phosphate dehydrogenase deficiency;
• you/your child have ever had a bad, unusual or allergic reaction to lidocaine or prilocaine, also available under brand names such as Xylocaine (lidocaine) and Citanest (prilocaine);
• you think you/your child may be sensitive or allergic to other ingredients of the cream or Tegaderm dressing
• there is an infection, skin rash or cut at, or near, the area where you want to apply EMLA Cream;
• you/your child have atopic dermatitis, eczema or any other skin problems or diseases;
• you/your child have severe kidney or liver disease
• you are pregnant, trying to become pregnant or are breast-feeding;
• you would like to use EMLA Cream prior to treatment of a leg ulcer(s);
• you would like to use EMLA Cream on the genital area of children.

Serious Warnings and Precautions

EMLA Cream is for use on healthy, unbroken skin. Do not apply to open wounds, nor to burns or rashes or other skin conditions, including diaper rash.

BEFORE you use EMLA Cream talk to your doctor or pharmacist if:

• you/your child have glucose-6-phosphate dehydrogenase deficiency;
• you/your child have ever had a bad, unusual or allergic reaction to lidocaine or prilocaine, also available under brand names such as Xylocaine (lidocaine) and Citanest (prilocaine);
• you think you/your child may be sensitive or allergic to other ingredients of the cream or Tegaderm dressing
• there is an infection, skin rash or cut at, or near, the area where you want to apply EMLA Cream;
• you/your child have atopic dermatitis, eczema or any other skin problems or diseases;
• you/your child have severe kidney or liver disease
• you are pregnant, trying to become pregnant or are breast-feeding;
• you would like to use EMLA Cream prior to treatment of a leg ulcer(s);
• you would like to use EMLA Cream on the genital area of children.

Tell your doctor or pharmacist about any other drugs you take or have recently taken, including the ones you can buy without a prescription, including:

• antiarrhythmic drugs for heart problems (e.g. mexilitine, amiodarone);
• other anesthetics;
• other drugs which may trigger methomoglobin formation, including: sulfonamides, acetanilide, aniline dyes, benzocaine (or other “-caine” type anesthetics), chloroquine, dapsone, naphthalene, nitrates or nitrites, nitrofurantoin, nitroglycerin, nitroprusside, pamaquine, para-aminosalicylic acid, phenacetin, phenobarbital, phenytoin, primaquine, quinine and high doses of acetaminophen.

Usual dose:

If your doctor tells you to use EMLA Cream, follow your doctor's instructions for use. In any other situation, follow the directions below.

Do not put EMLA Cream near the eyes, as it may cause some irritation. If you accidentally get EMLA in the eye, rinse it well with lukewarm water and protect it until sensation returns.

Do not apply EMLA Cream inside the ear. Do not put EMLA Cream in the mouth, or swallow it. If EMLA Cream is accidentally swallowed, call your doctor.

Do not re-use EMLA Cream dressings once applied.

The numbing effect of EMLA starts working about 1 hour after it is applied. You may still feel pressure and touch in the area where you apply EMLA. The numbness of the skin may continue to increase after the cream is removed, and will last for at least 2 hours following a 1-2 hour application.

If you feel that the effect of EMLA Cream is too strong or too weak, tell your doctor or pharmacist.

Conditions where adjustments in dose may be required

• elderly patients
• acutely ill patients
• patients with severe liver disease
• patients with severe kidney disease
• patients also treated with other anesthetics or certain antiarrhythmic drugs (e.g. mexilitine, amiodarone)
• patients with skin conditions such as atopic dermatitis or molluscum contagiosum

EMLA should be used with caution in these patients, who may be more sensitive to the effects of lidocaine and prilocaine.

Talk to your doctor if you have skin problems such as atopic dermatitis or eczema.

Adults:

Be careful to apply no more than the maximum recommended dose of EMLA Cream.

Serious and life threatening side effects have occurred when EMLA Cream was used on large areas of skin for topical analgesia during cosmetic procedures.

Dosage of EMLA Cream on Healthy Skin:

For minor procedures on skin such as surgical treatment of lesions or when getting a needle or having blood taken, apply a thick layer of cream, about half of a 5 g tube (2 g), on an area slightly larger than a two dollar coin or “toonie”. After covering EMLA Cream with an air-tight dressing, leave on for at least 1 hour. It is important to cover EMLA Cream with an air-tight dressing to ensure that the cream penetrates the skin properly and numbness of the area is felt.

Your doctor may use EMLA Cream on larger areas for such procedures as split-skin grafting. If you are instructed by the doctor to apply EMLA Cream yourself for this procedure, apply a thick layer of cream to the area to be treated (about 1.5 to 2 g/10 cm2; 1.5 to 2 g is about half of a 5 g tube; a 10 cm2 area is a little larger than the size of a two dollar coin or "toonie"). Make sure your doctor has clearly explained the size of the area to be treated. Leave the EMLA Cream on for at least 2 hours.

You will not get any added benefit from leaving EMLA Cream on for longer than 5 hours.

1 g of EMLA Cream administered from the 30 g aluminium tube is equivalent to a ribbon of cream of approximately 3.5 cm (or approximately 1.5 inches).

Dosage of EMLA Cream on Leg Ulcers:

Talk to your doctor before using EMLA Cream on leg ulcers.

For topical anesthesia before cleansing of leg ulcer(s), apply a thick layer of EMLA Cream over the leg ulcer(s), about 1 to 2 g/10 cm2 (a little larger than the size of a two dollar coin or "toonie"). Use no more than 10 g (two 5 g tubes).

After covering EMLA Cream with an air-tight dressing, leave on the leg ulcer for at least 30 minutes. Leaving EMLA Cream on for 60 minutes may improve the anesthesia. The cleansing of the leg ulcer should begin within 10 minutes after removing the cream.

When used on leg ulcers, discard the tube of EMLA Cream with any remaining contents after each treatment.

Dosage of EMLA Cream on Genital Mucosa:

Talk to your doctor before using EMLA Cream on the genital mucosa. For best results, do not apply EMLA Cream on the genital mucosa until you are with your doctor.

For needle insertion, use half of a 5 g tube (2 g) at the selected site before the procedure.

For the surgical treatment of small lesions, such as the removal of genital warts or when having a biopsy, use about half of a 5 g tube (2 g) per lesion 5 to 10 minutes before the procedure.

You do not need an airtight dressing when using EMLA Cream on the genital mucosa. Your doctor should begin the surgical procedure immediately after removing the cream.

Pediatrics:

Be careful to apply no more than the maximum recommended dose of EMLA Cream.

Children should be closely observed during and after use of topical anesthetics, as they are at greater risk than adults for serious side effects, such as methemoglobinemia (a blood disorder that causes the skin, especially around lips and nails, to turn brownish or greyish).

For children under the age of 6: take care not to apply more EMLA Cream or give it more frequently than the doctor recommended. Please make sure that your child does not ingest any of the cream.

When using EMLA Cream for your child's pain relief, remember it is also very important to provide comfort and emotional support.

For minor skin procedures. It is important to cover EMLA Cream with an air-tight dressing to ensure that the cream penetrates the skin properly and numbness of the area is felt.

In children, EMLA Cream should only be applied to healthy, unbroken skin.

Do not apply EMLA Cream to infants under 3 months of age unless a doctor tells you to do so. Infants under 3 months of age are at a higher risk than older children for methemoglobinemia. This is a condition in which there is not enough oxygen in the blood, and it can be caused by an overdose of EMLA.

Neonates Under the Age of 3 Months (ONLY IF INSTRUCTED BY A DOCTOR):

Apply up to 1 g of cream on a skin area not larger than 10 cm2 (a little larger than the size of a two dollar coin or “toonie”). After covering EMLA Cream with an air-tight dressing, leave on for 1 hour. DO NOT LEAVE EMLA ON THE SKIN FOR LONGER THAN 1 HOUR.

Infants Between 3 and 12 Months of Age:

Apply up to 2 g of cream on a total skin area not larger than 20 cm2 (a little larger than the size of a credit card). After covering EMLA Cream with an air-tight dressing, leave on for at least 1 hour. Do not leave on the skin for more than 4 hours.

Children Between 1-6 Years:

Apply up to 10 g of cream on a total skin area not larger than 100 cm2 (a little larger than the size of two credit cards). After covering EMLA Cream with an air-tight dressing, leave on for at least 1 hour. Do not leave on the skin for more than 5 hours.

Children Between 7-12 Years:

Apply up to 20 g of cream on a total skin area not larger than 200 cm2 (a little larger than a standard postcard). After covering EMLA Cream with an air-tight dressing, leave on for at least 1 hour. Do not leave on the skin for more than 5 hours.

Overdose:

In case of EMLA overdose or if you think you, or anyone else, are experiencing any of the side effects described below or methemoglobinemia, contact your doctor, hospital emergency department or regional Poison Control Centre immediately. You may require medical attention.

You should not take XYLOCAINE if you have any of the following:

• Heart conditions like Adams-Stokes syndrome or heart blocks without a pacemaker
• Congestive heart failure (CHF) or heart shock

Talk to your doctor before taking XYLOCAINE if you are taking drugs called beta-blockers, including Inderal (propranolol), Bystolic (nebivolol), Lopressor (metoprolol tartrate), and Toprol XL (metoprolol succinate).

To date, whether XYLOCAINE can help prevent a heart attack remains much-debated. If you have any concerns about this issue, talk to your doctor.

XYLOCAINE Warnings

In 2014, the Food and Drug Administration (FDA) issued a black-box warning for XYLOCAINE because of its danger in small children.

The FDA warns that XYLOCAINE should not be used to relieve tooth pain in teething babies, because XYLOCAINE is easily absorbed into the bloodstream and may cause death.

Pregnancy and XYLOCAINE

XYLOCAINE is an FDA Pregnancy Category B drug, which means it is generally safe to use during pregnancy because there is low risk of harm for your developing baby.

Regardless, you should tell your doctor if you are pregnant or plan to become pregnant before taking this medication.

You should also alert your physician if you are breastfeeding or plan to breastfeed before using XYLOCAINE.

Common Side Effects of XYLOCAINE

• High blood pressure
• Swelling or swelling or redness of the skin at the site of injection if receiving XYLOCAINE via injection into the veins
• Constipation, nausea, and/or vomiting
• Confusion, dizziness, headache, funny feeling or tingling in the toes, fingers, or hands

Serious Side Effects

• Changes in heart rhythm
• Methemoglobinemia, a very rare-yet-serious blood disorder caused by the blood not being able to carry as much oxygen as it normally would
• A condition called malignant hyperthermia where body temperature can rise as high as 113 degrees Fahrenheit with fever, sweating, racing, heartbeat, muscle pain
• Seizures
• Anaphylaxis, a sudden, severe, and life-threatening allergic reaction where your tongue and throat swell, your throat may close, you break out in hives, your blood drops to a dangerously low level, and you have trouble breathing

Rare Side Effects

XYLOCAINE may cause some unpredictable side effects including baldness and dizziness.

It is always important to share with your doctor and pharmacist all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking.

You should not take XYLOCAINE if you are taking the following drugs:

• Exparel (bupivacaine liposome)
• Tikosyn (dofetilide)
• Cerdelga (eliglustat)
• Juxtapid (Lomitapide)

Talk to your doctor first about taking XYLOCAINE if you are taking any of the following:

• Inlyta (axitinib)
• Bosulif (bosutinib)
• Luvox (fluvoxamine)
• Lexiva (fosamprenavir)
• Kalydeco (Ivacaftor)
• Mefloquine
• Dilantin (phenytoin)
• Orap (pimozide)
• Pomalyst (pomalidomide)

XYLOCAINE and Alcohol

Since there is a possibility that XYLOCAINE may enter the bloodstream when using the patch or the cream forms, people wearing the patch, and those undergoing surgeries and other procedures for which they receive XYLOCAINE, should avoid drinking.

XYLOCAINE and Grapefruit Juice

XYLOCAINE may interact with grapefruit juice, so for best results, avoid drinking grapefruit juice while taking XYLOCAINE.

Apply XYLOCAINE patches directly to the affected area and leave it on for 12 hours. Then remove the patch and wait 12 hours before applying a new patch.

XYLOCAINE is also available over-the-counter in creams for pain relief or in combination with other medications via prescription.

XYLOCAINE solution for injection should only be administered by appropriate medical professionals.

XYLOCAINE Overdose

If you suspect an overdose, contact a poison control center or emergency room immediately.

Missed Dose of XYLOCAINE

If you miss a dose of XYLOCAINE, try to take it as soon as you remember.

However, if it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Don't double up to make up for a missed dose.