Imitrex (Sumatriptan)

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Imitrex 100mg

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Imitrex 50mg

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Imitrex (Sumatriptan) Medication Information

Uses

Imitrex is a serotonin receptor blocker that is used to treat migraines with and without aura.

Dosage

The tablets are available in several strengths:

  • 25 mg
  • 50 mg
  • 100 mg

Side Effects

The most common side effects of Imitrex include:

  • Chest pain
  • Vertigo
  • Fatigue
  • Warm/cold sensation

Speak with your doctor for a full list of side effects that apply to you if you are taking Imitrex.

Precautions

Perform cardiac evaluation in patients with several cardiovascular risk factors. 

If arrhythmias occur, Imitrex should be stopped.

If brain hemorrhage or strokes occur, Imitrex should be stopped

If you overuse Imitrex, it can cause an overuse headache, which may require Imitrex detoxification.

Serotonin syndrome can occur with Imitrex, especially if other serotonin medications are used at the same time, if this occurs stop Imitrex.

Imitrex should be used cautiously in patients with a history of seizures. 

Interactions

Common medications that interact with Imitrex are listed:

  • MAOIs
  • SSRIs
  • SNRIs
  • Ergot containing drugs

Speak with your doctor for more information and before starting a new medication with Imitrex. 

Storage

Store between 36-86ºF.    

Pharmacist Tips

  • Imitrex can cause serious cardiac issues, including heart attack and stroke. 
  • The use of Imitrex within 24 hours of another triptan is contraindicated. 
  • There is a risk of serotonin syndrome, and you should be monitored for symptoms.

Sumatriptan FAQs

Why is Sumatriptan restricted?

Imitrex can interact with several common medications, in addition it can cause serious cardiac events, so it use should be limited. 

 

What can you not take with Imitrex?

You should not take Imitrex if you have used other triptans or serotonin medications in the last 24 hours. 

 

How does Sumatriptan make you feel?

The most common side effects seen with Imitrex are pressure or pain in your neck, jaw, throat, and chest, having a warm/cold sensation, and tingling on the skin.

 

Is it okay to take Sumatriptan daily?

Do not take Imitrex more than prescribed by your doctor. 

 

How fast does Imitrex work?

Typically, you should see a resolution in your migraine within 2 hours of taking Imitrex.

 

Related Drugs

Reference:

Imitrex {package insert}. Research Triangle Park, NC: GlaxoSmithKline; 2013.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020132s028,020626s025lbl.pdf

PharmD Medical Writer

Author: Dr. Larisa Roybal, PharmD

Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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