Relpax (Eletriptan)

(℞) Prescription Required

    Relpax (Eletriptan) Dosage and Side Effects

    RELPAX is intended to relieve your migraine headache and other associated symptoms of a migraine attack.

    Warnings and Precautions

    The decision to use RELPAX is one that you and your doctor should make jointly, taking into account your individual preferences and medical circumstances. If you have risk factors for heart disease (such as high blood pressure, high cholesterol, obesity, diabetes, smoking, strong family history of heart disease, or you are a postmenopausal female or a male over 40), you should tell your doctor. Your doctor should evaluate you for heart disease in order to determine if RELPAX is appropriate for you.

    Important Questions to Consider Before Taking RELPAX:

    If the answer to any of the following questions is yes, or if you do not know the answer, then please speak with your doctor before you take any RELPAX.

    • Are you pregnant? Do you think you might be pregnant? Are you trying to become pregnant? Are you using inadequate contraception? Are you breast-feeding?
    • Do you experience or have you ever experienced any pain or tightness in the chest, (which may or may not spread to your neck, jaw, or upper arm), shortness of breath, rapid heartbeats or irregular heartbeats? Do you have angina?
    • Have you ever had heart or blood vessel disease? Have you had a heart attack or stroke? Have you ever had Raynaud syndrome or transient ischemic attacks (TIAs)?
    • Do you have risk factors for heart disease, such as: high blood pressure, high cholesterol, smoking, obesity, diabetes, or strong family history of heart disease? Are you postmenopausal, or a male over 40?
    • Have you ever had to stop taking this or any other medication because of an allergy or other problems?
    • Are you taking any other migraine 5-HT1 agonist medications such as Axert (almotriptan), Imitrex (sumatriptan succinate/sumatriptan), Amerge (naratriptan as naratriptan hydrochloride), Zomig (zolmitriptan), Maxalt (rizatriptan benzoate) or migraine medications containing ergotamine, dihydroergotamine, or methysergide?
    • Are you taking any medications for depression such as selective serotonin reuptake inhibitors (SSRIs) such as sertraline, escitalopram and fluoxetine, or serotonin norepinephrine reuptake inhibitors (SNRIs) such as venlafaxine, duloxetine?
    • Have you ever experienced numbness on one side of your body when you have a headache?
    • Have you ever had, or do you have epilepsy or seizures?
    • Have you ever had, or do you have liver disease or kidney disease?
    • Is this headache different from your usual migraine attacks?
    • Are you over 65 years of age?
    • Have you taken or will you be taking any of the following medicines within 72 hours: ketoconazole (Nizoral), itraconazole (Sporanox), nefazodone (Serzone), troleandomycin (TAO), clarithromycin (Biaxin), ritonavir (Norvir), and nelfinavir (Viracept)? These medicines may cause an increase in the amount of RELPAX in the blood increasing the risk of serious side effects.

    If you answered yes to any of the above questions, discuss them all with your physician before taking RELPAX.

    Side Effects

    Side Effects to Watch for:

    Although the vast majority of RELPAX users have not experienced any significant problems, you should be aware of the following side effects:

    • Sensations of pain, pressure or tightness in the chest, neck, throat, jaw or arms. If this happens to you, then discuss it with your doctor before using any more RELPAX. If the chest pain is severe (may resemble an angina attack) or does not go away, call your doctor immediately.
    • Shortness of breath; wheezing; heart throbbing; swelling of face, lips, eyelids; skin rash; skin lumps; or hives. Tell your doctor immediately. Do not continue to take RELPAX unless advised by your doctor.
    • Feeling weak, dizziness, feeling sleepy or drowsy, tingling, difficulty swallowing, nausea and stomach pain/cramps.
    • Drowsiness in some patients. Dizziness and drowsiness have also been reported in some patients receiving RELPAX. Therefore, do not drive or operate machinery if you are experiencing these symptoms or side effects.

    If you feel unwell in any other way or have any symptoms that you do not understand, contact your doctor or pharmacist.

    This is not a complete list of side effects. For any unexpected effects while taking RELPAX, contact your doctor or pharmacist.

    Interactions with this medication

    Some medicines may increase the risk of serious side effects if taken concurrently with RELPAX.

    Do not take RELPAX if you:

    • have taken any of the following medicines in the last 72 hours: ketoconazole (Nizoral), itraconazole (Sporanox), nefazodone (Serzone), troleandomycin (TAO), clarithromycin (Biaxin), ritonavir (Norvir), and nelfinavir (Viracept)?
    • have taken the following medicines in the last 24 hours: other “triptans” like almotriptan (Axert), sumatriptan (Imitrex), naratriptan (Amerge), zolmitriptan (Zomig), rizatriptan (Maxalt) or ergotamine-type medications such as ergotamine, dihydroergotamine or methysergide.

    Ask your physician for instructions about taking RELPAX if you are taking selective serotonin reuptake inhibitors (SSRIs) such as sertraline, escitalopram and fluoxetine or serotonin norepinephrine reuptake inhibitors (SNRIs) such as venlafaxine, duloxetine for depression. A life-threatening condition called serotonin syndrome can happen when medicines called triptans, such as RELPAX, and medicines used to treat depression and mood disorders called SSRIs or SNRIs are used together. Signs and symptoms of serotonin syndrome include the following: restlessness, diarrhea, hallucinations, coma, loss of coordination, nausea, fast heart beat, vomiting, increased body temperature, changes in blood pressure and overactive reflexes.

    Proper Use of this medication

    Usual dose:

    For adults, the dosage is 20 or 40 mg, as recommended by your physician. The dose should be taken as soon as your migraine appears, but it may be taken at any time during your migraine headache.

    RELPAX tablets should be swallowed whole with water.

    If your first dose is 20 mg, a second dose of 20 mg may be taken if your headache returns. Repeat doses cannot be taken any sooner than 2 hours following the first dose. Do not take more than 40 mg in any 24-hour period.

    If the first dose does not relieve the symptoms, do not take further doses for the same attack.

    A reminder: This medicine has been prescribed only for you. Only a doctor knows who can use it safely. Never give this medication to anyone else. It may harm them, even if their symptoms are the same as yours.

    Overdose:

    If you have taken more medication than your physician has instructed, contact either your physician, hospital emergency department, or nearest poison control centre immediately.

    Other related products

    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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