Axert (Almotriptan)

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Axert 12.5mg

Product of United Kingdom
Manufactured by: Almirall Limited
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Axert is also marketed Almogran in the United Kingdom
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Axert 12.5mg
Product of United Kingdom
Manufactured by Almirall Limited
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Almotriptan 6.25mg

Product of Canada
Manufactured by: Mylan
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Almotriptan 6.25mg
Product of Canada
Manufactured by Mylan
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Almotriptan 12.5mg

Product of Canada
Manufactured by: Teva Pharmaceuticals
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Almotriptan 12.5mg
Product of Canada
Manufactured by Teva Pharmaceuticals
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Axert (Almotriptan) Product Information

Axert is used to treat migraines and other types of headaches in adults, and children over 12. It is a triptan medication, that helps treat migraines by stimulating serotonin. Serotonin is a neurotransmitter that is found in the brain that constricts the blood vessels and reduces inflammation, so headaches and migraines are eased.

When taking Axert, the blood vessels around the brain will be narrowed and as a result, it will be less pain felt. This medication will also work to prevent the production of substances that will lead to the feeling of pain and nausea. Almotriptan can work on both adults and those over 12 years of age.

Almotriptan is not able to stop headaches or migraines from starting, but it will help deal with the pain once they have started. It should not be used if the headache is a tension headache or if there is a feeling that there are different symptoms to normal.

Buy Generic Axert Online at PricePro Pharmacy

We have two dosages of Axert available, made by different manufacturers. Axert 6.25mg is manufactured by McNeil Consumer Healthcare, and starts at $124.00 USD price for 6 tablets. Almirall Limited is the name of the manufacturer of Axert 12.5mg which starts at $65.00 USD price for 6 tablets. There are generics available in both strengths as well. The generic name is known as Almotriptan. Generic Axert is available at a lower cost.

Depending on the product you choose and what is available, your order will be shipped from the UK or Canada. You can expect your order to arrive within 7-10 business days of being shipped, for deliveries going  to the United States.

Standard shipping is $9.95, but tracked shipping is available for $15.00.

Our toll free number is 1-855-776-0079 or you can reach us by chat if you have any questions or need assistance.

Axert (Almotriptan Malate) Medication Information

Uses

Axert is a 5HT1B/1D receptor agonist (triptan) indicated for: 

  • Acute treatment of migraine attacks in adults with a history of migraine with or without aura.
  • Acute treatment of migraine headache pain in adolescents age 12 to 17 years with a history of migraine with or without aura, and who have migraine attacks usually lasting 4 hours or more.

Dosage

There are oral tablets available in several different strengths:

  • 6.25 mg
  • 12.5 mg

Side Effects

The most common side effects of Axert include:

  • Nausea/vomiting
  • Dry mouth
  • Paresthesia
  • Dizziness
  • Somnolence
  • Headache

Speak with your doctor or pharmacist for a full list of side effects that applies to you.

Precautions

Serious adverse cardiac events, including acute myocardial infarction, and life-threatening disturbances of cardiac rhythm.

It is strongly recommended that Axert not be given to patients in whom unrecognized coronary artery disease (CAD) is predicted by the presence of risk factors. In very rare cases, serious cardiovascular events have been reported in association with Axert use in the absence of known cardiovascular disease. If Axert is considered, patients should first have a cardiovascular evaluation. If the evaluation is satisfactory, first dose should take place in a physician’s office setting.

Sensations of pain, tightness, pressure and heaviness in the chest, throat, neck and jaw: generally not associated with myocardial ischemia, but patients with signs or symptoms suggestive of angina should be evaluated for the presence of CAD.

Cerebrovascular events, some fatal.

Gastrointestinal ischemic events and peripheral vasospastic reactions (e.g. Raynaud’s syndrome). 

Potentially life-threatening serotonin syndrome, particularly in combination with selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs). Monitor patients for neurologic changes and gastrointestinal symptoms if concomitant treatment is clinically warranted.

Increase in blood pressure, very rarely associated with significant clinical events.

Use with caution in patients with a known hypersensitivity to sulfonamides.

Interactions

Some of the common drug interactions with Axert:

  • Ergotamine-containing medication
  • Triptans
  • SSRIs
  • SNRIs
  • Ketoconazole 

For a more complete list speak with your doctor or pharmacist 

Storage

Store at controlled room temperature (77ºF).

Pharmacist Tips

  • There is a risk of serotonin syndrome with the use of Axert or other triptans, particularly during combined use with selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs)
  • AXERT may cause dizziness, somnolence, visual disturbances and other CNS symptoms that can interfere with driving or operating machinery.
  • Tell your physician if you develop a rash, itching, or breathing difficulties after taking Axert.
  • The choice of dose should be made on an individual basis.

Almotriptan FAQs

Can I repeat my dose?

If the headache is relieved after the initial Axert dose but returns, the dose may be repeated after 2 hours. The effectiveness of a second dose has not been established in placebo-controlled trials. The maximum daily dose should not exceed 25 mg.

 

Can I take this if I am pregnant?

There are no adequate and well-controlled studies in pregnant women; therefore, Axert should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

 

Can I take this while breastfeeding?

It is not known whether almotriptan is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Axert is administered to a nursing woman.

 

How does Axert work during a migraine attack?

Axert reduces swelling of blood vessels surrounding the brain. This swelling is associated with the headache pain of a migraine attack. It also blocks the release of substances from nerve endings that cause more pain and other symptoms of migraine. Finally it interrupts the sending of specific pain signals to your brain.

 

What can trigger a migraine attack?

Certain things may trigger migraine attacks in some people. Some of these triggers are:

  • Certain foods or drinks, such as cheese, chocolate, citrus fruit (oranges, grapefruit, lemons, lime, and others), caffeine, and alcohol. 
  • Stress. 
  • Change in behavior, such as too much or too little sleep, missing a meal, or a change in diet.
  • Hormone changes in women, such as during monthly menstrual periods.

 

What should I do in the case of an overdose?

Call your doctor or poison control center or go to the ER.

 

Related Drugs

Reference:

Axert {package insert}. Gurabo, Puerto Rico: Janssen-Ortho, LLC; 2009.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021001s010s011lbl.pdf

PharmD Medical Writer

Author: Dr. Larisa Roybal, PharmD

Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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