Retrovir (Zidovudine)

Author , posted on June 16, 2017

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Retrovir

Zidovudine

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Zidovudine (Generic)

Zidovudine

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Retrovir (Zidovudine) Dosage and Side Effects

RETROVIR (AZT) is prescribed to slow down the effects of HIV virus.

Warnings and Precautions

BEFORE you use RETROVIR (AZT) talk to your doctor or pharmacist if:

  • you are allergic to any ingredient in this medicine.
  • you have bone marrow problems (low blood cell counts).
  • you have hepatomegaly (enlarged liver), hepatitis (inflamed liver) or other known risk factors for liver disease.
  • you have kidney disease.
  • you are taking other drugs
  • you are pregnant or breastfeeding.
  • your baby or infant was exposed to Nucleoside Reverse Transcriptase Inhibitors (NRTIs) during pregnancy or labour.
  • you are taking ribavirin as it could cause or worsen anemia (symptoms of tiredness, shortness of breath).
  • Your doctor will advise whether you should stop taking RETROVIR (AZT).

Illness associated with HIV infection, including other infections, may still happen. Therefore, it is very important to keep appointments with your doctor and to report any change in your health as it occurs.

RETROVIR (AZT) has been extensively studied in humans for limited periods of time. Studies have shown that treatment will benefit your health. However, the effectiveness and overall safety of RETROVIR (AZT) is unknown beyond the length of time for which it has been studied.

The effectiveness and overall safety of RETROVIR (AZT) in women, intravenous drug users, and ethnic minorities are not different than that observed in white males.

Solution for Infusion:

The rubber stopper of the RETROVIR (AZT) intravenous vials contains latex. Tell your doctor if you are allergic to latex.

Use of This Medication During Pregnancy and Breast Feeding:

Before you use RETROVIR (AZT), talk to your doctor or pharmacist if you are pregnant, planning to become pregnant, or become pregnant while taking RETROVIR (AZT). It is not known if RETROVIR (AZT) can harm your unborn child. You and your doctor will need to decide if taking RETROVIR (AZT) is right for you. If you take RETROVIR (AZT) while you are pregnant, talk to your doctor about how you can be included in the Antiretroviral Pregnancy Registry.

For pregnant women who are considering the use of RETROVIR (AZT) during pregnancy for the prevention of HIV-transmission to their infants, it is important to understand that transmission may still occur in some cases (about 8%) despite using RETROVIR (AZT). The long-term safety in treated fetuses, neonates, or infants has not been established.

Babies and infants exposed to Nucleoside Reverse Transcriptase Inhibitors (NRTIs) during pregnancy or labour, show minor temporary increases in blood levels of lactate. The clinical importance of these temporary increases is unknown.

There have been very rare reports of diseases that affect the nervous system such as delayed development and seizures.

These findings do not affect current recommendations to use antiretroviral therapy in pregnant women to prevent transmission of HIV to their babies.

HIV-infected women should not breast-feed in order to prevent transmission of HIV to a child who may not yet be infected. The ingredients in RETROVIR (AZT) can also pass into your breast-milk.

Side Effects

Side-effects of RETROVIR (AZT) include nausea, vomiting, fever, headache, stomach pain, loss of appetite, muscle pain, low white blood cell count (neutropenia or leucopenia), decrease in the number of cells involved in blood clotting (thrombocytopenia) or in all kinds of blood cells (pancytopenia), reduction in the number of red blood cells (pure red cell aplasia), failure of the bone marrow to produce new blood cells (aplastic anaemia), an increase in lactic acid, feeling depressed or anxious, dizziness, not being able to sleep, tingly feelings in the skin (pins and needles), not being able to concentrate, feeling drowsy, seizures, disease of the heart muscle, cough, intestinal gas, changes in the colour of the nails, skin, or the skin inside the mouth, taste disturbance, indigestion, skin rash (red, raised or itchy skin), sweating, passing urine more often, enlarged breasts in men, general aches and pain, chills, chest pain, flu-like feeling. If these become bothersome, consult your doctor.

Changes in your immune system (Immune Reconstitution Syndrome) can happen when you start taking HIV medicines. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time, or you could develop an autoimmune disease in which your immune system reacts against your own body (e.g. Graves' disease (which affects the thyroid gland), Guillain-Barré syndrome (which affects the nervous system) or polymyositis (which affects the muscles) and it may develop at any time, sometimes months later after the start of HIV therapy). Sometimes symptoms can be severe, so if you develop high temperature (fever), joint or muscle pain, redness, rash, swelling, or fatigue or any new symptoms contact your doctor straight away.

An important but reversible side-effect of RETROVIR (AZT), particularly in patients with more severe disease, can be a decrease in certain types of blood counts (including red blood cells, white blood cells and platelets) and increase in certain liver enzymes. Since a reduction in these cells can directly affect your health, it is important to have your blood tested as often as your doctor requests it. In some cases, it may be necessary to adjust the dose of the drug, temporarily discontinue the drug, give a blood transfusion, or stop the drug altogether.

It is important to understand that although these blood effects can occur at any stage, they are much more common in advanced disease and in patients who start RETROVIR (AZT) therapy late in their illness.

Contact your doctor if you experience muscle weakness, shortness of breath, symptoms of hepatitis or pancreatitis (which include very severe stomach cramps) or any other unexpected adverse events while being treated with RETROVIR (AZT).

This is not a complete list of side effects. For any unexpected effects while taking RETROVIR (AZT), contact your doctor or pharmacist.

Interactions with this medication

Some drugs may change the usefulness and safety of RETROVIR (AZT). It is therefore very important that you tell your doctor before you decide to take any new drugs, even if these are available without a prescription.

Drugs that may interact with RETROVIR (AZT) include: atovaquone, bone marrow suppressive agents/cytotoxic agents, clarithromycin, fluconazole, ganciclovir, interferon-alpha, lamivudine, methadone, phenytoin, probenecid, stavudine, valproic acid, and others such as trimethoprim-sulfamethoxazole, pyrimethamine, acyclovir and rifampin.

For patients receiving combination therapy with RETROVIR (AZT) and zalcitabine, it is important to understand that the major toxicity of zalcitabine is peripheral neuropathy. Pancreatitis is another serious and potentially life-threatening toxicity that has been reported in less than 1% of patients treated with zalcitabine alone. Symptoms of peripheral neuropathy include tingling, burning, pain, or numbness in the hands or feet. Symptoms of pancreatitis include abdominal pain, nausea and vomiting. These symptoms should be promptly reported to your physician. Since the development of peripheral neuropathy seems to be dose-related to zalcitabine, you should follow your physician's instructions regarding the prescribed dose. The long-term effects of zalcitabine in combination with RETROVIR (AZT) are presently unknown. If you are a female of child-bearing age, you should use effective contraception while using zalcitabine.

An additional precaution is that some other drugs may change the usefulness and safety of RETROVIR (AZT).

Proper Use of this medication

Usual dose:

You should be counselled about the use of RETROVIR (AZT).

It is important to take RETROVIR (AZT) exactly as prescribed. Altering the dose without the direct advice of your physician is unwise, as is sharing your medication with others.

Oral Administration:

Adults and Adolescents 30 kg and Over:

The recommended total oral daily dose of RETROVIR (AZT) is 600 mg per day in divided doses in combination with other antiretroviral agents. Suggested Dosing Regimens:

  • Capsules: three 100 mg RETROVIR (AZT) capsules every 12 hours; OR two 100 mg RETROVIR (AZT) capsules every 8 hours.
  • Syrup: 6 teaspoonfuls (30 mL) RETROVIR (AZT) syrup every 12 hours; OR 4 teaspoonfuls (20 mL) RETROVIR (AZT) syrup every 8 hours.

Children (≥4 kg):

The recommended oral dose in children weighing ≥4 kg

Children should be assessed for the ability to swallow capsules. If a child has difficulty in swallowing a RETROVIR (AZT) capsule, the RETROVIR (AZT) syrup formulation should be prescribed.

RETROVIR (AZT) Syrup is available for dosing children who weigh less than 30 kg. RETROVIR (AZT) Syrup should be used to provide accurate dosage when capsules are not appropriate.

Alternatively, dosing for RETROVIR can be based on body surface area (BSA) for each child. The usual dose of RETROVIR is 480 mg/m2per day, divided equally into two or three doses per day. In some cases the dose calculated by mg for each kg will not be the same as that calculated by BSA.

Children (<4 kg):

Available data are insufficient to propose specific dosing recommendations for children weighing <4 kg.

Solution for Infusion:

Adults and Adolescents 30 kg and Over:

The recommended dose is 1 to 2 mg/kg administered as a 1 hour infusion every 4 hours around the clock (6 times daily). RETROVIR (AZT) solution for infusion is administered intravenously at a constant rate over 1 hour. Rapid infusion or bolus injection should be avoided. RETROVIR (AZT) solution for infusion should not be given intramuscularly.

If you are also taking clarithromycin, your doctor may advise you to take this medication at least 2 hours before or 2 hours after RETROVIR(AZT), to avoid a drug interaction.

Children:

The recommended dose of RETROVIR (AZT) I.V. Injection in children 3 months to 12 years of age is 120 mg/m2 every 6 hours, infused over 1 hour (480 mg/m2 per day). Do not exceed 160 mg for any individual dose.

Prevention of Maternal-Fetal HIV Transmission:

The recommended dosing regimen for administration to pregnant women (>14 weeks of pregnancy) and their newborn infant is:

  • Maternal Dosing: 100 mg orally 5 times per day until the start of labour. During labour and delivery, intravenous RETROVIR (AZT) should be administered at 2 mg/kg (total body weight) over 1 hour followed by a continuous intravenous infusion at 1 mg/kg/h (total body weight) until clamping of the umbilical cord.
  • Infant Dosing: 2 mg/kg of oral solution every 6 hours starting within 12 hours after birth and continuing through 6 weeks of age. Infants unable to receive oral dosing may be administered RETROVIR (AZT) intravenously at 1.5 mg/kg, infused over 30 minutes, every 6 hours.

Overdose:

If you are concerned that you may have taken too much RETROVIR, contact a health care practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.

Other related products

Genvoya (Tenofovir Alafenamide, Elvitegravir, Cobicistat, Emtricitabine)

Author , posted on June 16, 2017

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Genvoya

Emtricitabine, Cobicistat, Elvitegravir, Tenofovir Alafenamide

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Genvoya

Emtricitabine, Cobicistat, Elvitegravir, Tenofovir Alafenamide

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Genvoya

Emtricitabine, Cobicistat, Elvitegravir, Tenofovir Alafenamide

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Genvoya (Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Alafenamide) Medication Information

Uses

Genvoya is an antiviral combination medication that is used to treat human immunosuppressant virus (HIV)

Dosage

The tablets are available in 150-150-200-10 mg strength. 

Side Effects

The most common side effects of Genvoya include:

  • Nausea
  • Diarrhea
  • Fatigue
  • Headache 

Speak with your doctor for a full list of side effects that apply to you if you are taking Genvoya.

Precautions

There is a risk of redistribution/accumulation of fat when taking Genvoya.

There is a risk of immune reconstitution with Genvoya, so patients can experience flu like symptoms when starting treatment. 

There is a risk of worsening of kidney function with Genvoya.

Interactions

The most common drug interactions with Genvoya include:

  • Ketoconazole
  • Clarithromycin
  • Phenytoin
  • Phenobarbital
  • Carbamazepine
  • SSRIs
  • SNRIs

Speak with your doctor for more information and before starting a new medication with Genvoya. 

Storage

Store below 86 ºF. Genvoya should be dispensed in the original container.

Pharmacist Tips

  • Taking Genvoya every day is very important to ensure the virus does not build a tolerance to the medication. 
  • Genvoya can cause kidney injury so your kidneys should be monitored. 
  • There is a risk of fat accumulation with Genvoya. 

Genvoya FAQs

What are the side effects of Genvoya?

The most common side effects of Genvoya are nausea, diarrhea, fatigue, and headache.

 

Should Genvoya be taken with food?

Genvoya should be take with food to help the body absorb the medication.

 

What is Genvoya used to treat?

Genvoya is used to treat HIV

 

What happens if I stop taking Genvoya?

Stopping Genvoya without doctor approval can result in a resurgence of HIV virus, which can make you very sick, and make it easier to pass the virus to others. 

 

Can Genvoya cause weight gain?

Genvoya does not typically cause weight gain.

 

Related Drugs

Reference:

Genvoya {package insert}. Foster City, CA: Gilead Science, Inc.; 2016.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/207561s002lbl.pdf

PharmD Medical Writer

Author: Dr. Larisa Roybal, PharmD

Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.

Daliresp (Roflumilast)

Author , posted on June 16, 2017

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Daxas

Roflumilast

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Daxas

Roflumilast

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Daliresp (Roflumilast) Dosage and Side Effects

DALIRESP is used treat of symptoms of severe chronic obstructive pulmonary disease (COPD).

Warnings and Precautions

You should not use DALIRESP if you have moderate or severe liver disease. You should not use DALIRESP if you are allergic to it, or if you have moderate or severe liver disease.

To make sure you can safely take DALIRESP , tell your doctor if you have any of these other conditions:

  • liver disease;
  • a history of depression, mental illness, or suicidal thoughts or actions.

You may have unusual thoughts or behavior, or thoughts about suicide, while taking this medicine. Tell your doctor if you have new or worsening depression, or suicidal thoughts. Your family or other caregivers should also be alert to changes in your mood or symptoms.

FDA pregnancy category C. It is not known whether DALIRESP will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. DALIRESP can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Do not give this medication to anyone under 18 years old without medical advice. Do not share this medication with other people, even if they have the same symptoms you have.

Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, depression, trouble sleeping, or if you feel impulsive, or you have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

  • rapid and unintended weight loss;
  • tremors;
  • pain or burning when you urinate;

Common side effects may include:

  • nausea, diarrhea;
  • loss of appetite, minor weight loss;
  • headache, dizziness;
  • occasional sleep problems;
  • back pain; or
  • flu symptoms.

Interactions with this medication

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Many drugs can interact with DALIRESP, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all medicines you use now and any medicine you start or stop using.

Proper Use of this medication

DALIRESP is usually taken once per day, with or without food. Follow your doctor's instructions. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

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Viramune XR (Nevirapine)

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Viramune XR

Nevirapine

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Nevirapine XR (Generic)

Nevirapine

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Viramune XR (Nevirapine) Dosage and Side Effects

VIRAMUNE XR is a medicine used to treat Human Immunodeficiency Virus (HIV) infection, the virus that causes AIDS (Acquired Immune Deficiency Syndrome).

Warnings and Precautions

Severe, life-threatening, and in some cases fatal liver toxicity, particularly in the first 18 weeks, has been reported in patients treated with VIRAMUNE, including pregnant women receiving chronic VIRAMUNE therapy in conjunction with other antiretroviral medication. Female gender and higher CD4 counts at the start of therapy may increase the risk of liver problems.

Severe skin and allergic reactions, including fatal cases have occurred with accompanying symptoms such as severe rash with fever, fatigue, muscle/joint pain, swelling of the face, hepatitis (liver inflammation), blood and kidney problems. If this occurs discontinue VIRAMUNE or VIRAMUNE XR and contact your doctor immediately.

In rare cases liver problems have led to liver failure and can lead to a liver transplant or death. Therefore, if you develop any of the following symptoms of liver problems stop taking VIRAMUNE or VIRAMUNE XR and call your doctor right away:

  • general ill feeling or “flu-like” symptoms
  • tiredness
  • nausea (feeling sick to your stomach)
  • lack of appetite
  • yellowing skin or whites of your eyes
  • dark urine (tea colored)
  • pale stools (bowel movements)
  • pain, ache, or sensitivity to touch on your right side below your ribs

Your doctor should check you and do blood tests often to check your liver function during the first 18 weeks of therapy. Checks for liver problems should continue regularly during treatment with VIRAMUNE or VIRAMUNE XR.

Skin Reactions:

Skin rash is the most common side effect of VIRAMUNE or VIRAMUNE XR. Most rashes occur in the first 6 weeks of treatment. In a small number of patients, rash can be serious and result in death. Therefore, if you develop a rash with any of the following symptoms, stop using VIRAMUNE or VIRAMUNE XR and call your doctor right away:

  • general ill feeling or “flu-like” symptoms
  • fever
  • muscle or joint aches
  • conjunctivitis (red or inflamed eyes, like “pinkeye”)
  • blisters
  • mouth sores
  • swelling of your face
  • tiredness
  • any symptoms of liver problems discussed above

If your doctor tells you to stop treatment with VIRAMUNE or VIRAMUNE XR because you have experienced the serious liver or skin reactions described above, never take VIRAMUNE or VIRAMUNE XR again.

These are not all the side effects of VIRAMUNE or VIRAMUNE XR. Tell your doctor if you have any side effects from VIRAMUNE or VIRAMUNE XR.

BEFORE you use VIRAMUNE or VIRAMUNE XR talk to your doctor or pharmacist:

  • If you have or have had any diseases of the liver particularly hepatitis B or C infection;
  • If you are pregnant or intend to become pregnant;
  • If you are a breast-feeding mother. It is recommended that HIV infected women not breastfeed, to avoid transmission of the virus to the infant;
  • If you are taking any medications, including prescription, non-prescription, herbal or homeopathic remedies;
  • If you have any allergies to foods or drugs;
  • If you are undergoing dialysis.

Side Effects

VIRAMUNE or VIRAMUNE XR can cause serious liver damage and skin reactions that can cause death. Any patients can experience such side effects, but some patients are more at risk than others.

Other common side effects of VIRAMUNE or VIRAMUNE XR include nausea, fatigue, fever, headache, vomiting, diarrhea, abdominal pain, skin rash and itching, myalgia (muscle pain) and arthralgia (joint pain). This list of side effects is not complete. Ask your doctor or pharmacist for more information.

Abnormal liver function test results, decrease in red blood cells or white blood cells called granulocytes, decrease in blood phosphorus, increase in blood pressure and hypersensitivity including severe allergic reaction with facial swelling may also occur.

If you feel unwell in any other way or have any symptoms that you do not understand, you should contact your doctor immediately.

Sleepiness can occur. Do not drive or operate machinery if you become drowsy.

Always tell your doctor or pharmacist about any undesirable effects you experience after taking VIRAMUNE or VIRAMUNE XR, even those not mentioned above.

Changes in body fat have been seen in some patients taking anti-retroviral therapy. These changes may include increased amount of fat in the upper back and neck (“buffalo hump”), breast, and around the trunk. Loss of fat from the legs, arms and face may also happen. The cause and long term health effects of these conditions are not known at this time.

Occasionally, the inactive ingredients of VIRAMUNE XR extended release tablets may be eliminated in the stool as a soft hydrated mass that looks like a whole tablet. There is no cause for alarm.

Consult your doctor immediately if you experience any symptoms as listed above, or any symptoms that you do not understand.

This is not a complete list of side effects. For any unexpected effects while taking VIRAMUNE or VIRAMUNE XR, contact your doctor or pharmacist.

Interactions with this medication

Drugs that may interact with VIRAMUNE or VIRAMUNE XR include:

VIRAMUNE or VIRAMUNE XR may change the effect of other medicines, and other medicines can change the effect of VIRAMUNE or VIRAMUNE XR. Tell your doctors and pharmacists about all medicines you take, including non-prescription medicines, vitamins and herbal supplements.

Do not take ketoconazole, rifampin, efavirenz, delavirdine, etravirine, rilpivirine, elvitegravir (in combination with cobicistat), or boceprevir; with VIRAMUNE or VIRAMUNE XR.

Tell your doctor if you take clarithromycin, fluconazole, methadone, rifabutin, indinavir, lopinavir/ritonavir combination, saquinavir or itraconazole.

VIRAMUNE or VIRAMUNE XR may not be right for you, or you may need careful monitoring.

You should be aware that VIRAMUNE or VIRAMUNE XR may change the effectiveness of oral contraceptives. Therefore oral contraceptives and other hormonal methods of birth control should not be used as a method of contraception in women taking VIRAMUNE or VIRAMUNE XR; other methods (barrier) must be used.

Proper Use of this medication

Usual dose:

Adult:

Follow the directions exactly as given to you by your doctor or pharmacist regarding the amount and frequency of dosing. The label will usually tell you this information as well. If you are not sure about dosing, ask your doctor or pharmacist.

VIRAMUNE Immediate Release Tablets:

As a general guide, swallow one tablet (200 mg) once a day for the first 14 days (this lead-in period should be used because it has been found to lessen the frequency of rash) followed by one 200 mg tablet twice daily as part of a multi-drug treatment program. VIRAMUNE immediate release tablets can be taken with or without food.

VIRAMUNE XR Extended Release Tablets:

Swallow one 200 mg tablet of VIRAMUNE immediate release once daily for the first 14 days to lessen the frequency of rash followed by one 400 mg tablet of VIRAMUNE XR extended release once daily. The VIRAMUNE XR extended release tablets should not be broken or chewed. VIRAMUNE XR extended release tablets can be taken with or without food.

It is important to strictly follow the once daily dose for the first 14 days. Do not start taking the 200 mg VIRAMUNE twice daily or the 400 mg VIRAMUNE XR once daily if you have any symptoms of liver problems or skin rash. The manufacturer's recommended dosage and monitoring for the other administered anti-retroviral drugs should be followed.

Patients Switching to VIRAMUNE XR Extended Release Tablets:

Patients already on a regimen of VIRAMUNE immediate release 200 mg twice daily in combination with other antiretroviral agents can be switched to VIRAMUNE XR extended release 400 mg once daily in combination with other antiretroviral agents without a lead-in period of VIRAMUNE immediate release.

Overdose:

In case of drug overdosage, contact a healthcare practitioner (e.g. doctor), hospital emergency department or regional Poison Control Centre, even if there are no symptoms.

Missed Dose:

If you miss a dose: If you forget to take your medicine, take it as soon as you remember. Then continue as before; do not double your next dosage.

If it is almost time for your next dose, do not take the missed dose. Instead, follow your regular dosing schedule by taking the next dose at its regular time.

If you stop taking VIRAMUNE or VIRAMUNE XR for more than 7 days, ask your doctor how much to take before you start taking it again. You may need to start with once-a-day 200 mg VIRAMUNE tablet dosing.

Avoid doing things that can spread HIV infection, as VIRAMUNE or VIRAMUNE XR does not stop you from passing HIV infection to others. Do not share needles, other injection equipment or personal items that can have blood or body fluids on them, like toothbrushes and razor blades. Always practice safe sex by using a latex or polyurethane condom to lower the chance of sexual contact with semen, vaginal secretions, or blood.

This medicine is for you. Never give it to someone else, as it may harm them even if their symptoms are the same as yours.

Take your medications exactly as prescribed by your doctor. Do not change the dose without consulting your doctor.

Do not take any other medication including prescription, non prescription, herbal or homeopathic remedies without your doctor's advice. Also, inform any other doctor, dentist or pharmacist you consult that you are taking this medication.

Keep out of reach of children.

If you have any other questions about VIRAMUNE or VIRAMUNE XR, contact your doctor or pharmacist.

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Viracept (Nelfinavir)

Author , posted on June 16, 2017

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Viracept

Nelfinavir Mesylate

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Viracept (Nelfinavir) Dosage and Side Effects

VIRACEPT is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body. VIRACEPT is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). VIRACEPT is not a cure for HIV or AIDS.

Warnings and Precautions

You should not use VIRACEPT if you have moderate to severe liver disease.

Serious drug interactions can occur when certain medicines are used together with VIRACEPT. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.

You should not take this medication if you are allergic to VIRACEPT, or if you have moderate or severe liver disease.

Some medicines can cause unwanted or dangerous effects when used with VIRACEPT. Your doctor may need to change your treatment plan if you use any of the following drugs:

  • alfuzosin;
  • pimozide;
  • rifampin;
  • sildenafil (Revatio for pulmonary arterial hypertension);
  • St. John's wort;
  • lovastatin or simvastatin;
  • dihydroergotamine, ergotamine, ergonovine, or methylergonovine;
  • amiodarone or quinidine; or
  • oral midazolam, or triazolam.

To make sure VIRACEPT is safe for you, tell your doctor if you have:

  • liver disease;
  • kidney disease;
  • diabetes;
  • a bleeding disorder such as hemophilia; or
  • high cholesterol or triglycerides.

This medication is not expected to be harmful to an unborn baby, but HIV can be passed to your baby if you are not properly treated during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant. Take all of your HIV medicines as directed to control your infection.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of VIRACEPT on the baby.

VIRACEPT can make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

You should not breast-feed while you are using VIRACEPT. Women with HIV or AIDS should not breast-feed at all. Even if your baby is born without HIV, you may still pass the virus to the baby in your breast milk.

VIRACEPT is not approved for use by anyone younger than 2 years old.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; or
  • high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss.

VIRACEPT may increase your risk of certain infections or autoimmune disorders by changing the way your immune system works. Symptoms may occur weeks or months after you start treatment with VIRACEPT. Tell your doctor if you have:

  • signs of a new infection--fever, night sweats, swollen glands, mouth sores, diarrhea, stomach pain, weight loss;
  • chest pain (especially when you breathe), dry cough, wheezing, feeling short of breath;
  • cold sores, sores on your genital or anal area;
  • rapid heart rate, feeling anxious or irritable, weakness or prickly feeling, problems with balance or eye movement;
  • trouble speaking or swallowing, severe lower back pain, loss of bladder or bowel control; or
  • swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence, loss of interest in sex.

Common side effects may include:

  • infections;
  • nausea, diarrhea, gas, stomach pain;
  • loss of appetite;
  • rash; or
  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Interactions with this medication

If you also take didanosine, take it 1 hour before or 2 hours after you take VIRACEPT.

Taking this medicine will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

Many drugs can interact with VIRACEPT. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

  • any other antiviral medicines to treat HIV;
  • bosentan;
  • carbamazepine;
  • colchicine;
  • fluticasone;
  • methadone;
  • midazolam injection;
  • omeprazole;
  • quetiapine;
  • salmeterol;
  • warfarin (Coumadin, Jantoven);
  • an antibiotic--azithromycin, rifabutin;
  • cholesterol medication--atorvastatin, rosuvastatin;
  • medicine to prevent organ transplant rejection--cyclosporine, sirolimus, tacrolimus;
  • medicine to treat impotence or pulmonary arterial hypertension--avanafil (Stendra), sildenafil (Viagra), tadalafil (Adcirca, Cialis), or vardenafil (Levitra, Staxyn); or
  • seizure medicine--phenobarbital, phenytoin.

This list is not complete and many other drugs can interact with VIRACEPT. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Proper Use of this medication

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

VIRACEPT works best if you take it with food.

Swallow the VIRACEPT tablet whole.

If you cannot swallow a whole tablet, dissolve it in a small amount of water. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

If a child is using this medicine, tell your doctor if the child has any changes in weight. VIRACEPT doses are based on weight in children, and any changes may affect your child's dose.

Use VIRACEPT regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

While using VIRACEPT, you may need frequent blood tests.

Store at room temperature away from moisture and heat.

Seek emergency medical attention or call the Poison Help line.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

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Viramune (Nevirapine)

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Viramune (Nevirapine) Dosage and Side Effects

VIRAMUNE is a medicine used to treat Human Immunodeficiency Virus (HIV) infection, the virus that causes AIDS (Acquired Immune Deficiency Syndrome).

Warnings and Precautions

Severe, life-threatening, and in some cases fatal liver toxicity, particularly in the first 18 weeks, has been reported in patients treated with VIRAMUNE, including pregnant women receiving chronic VIRAMUNE therapy in conjunction with other antiretroviral medication. Female gender and higher CD4 counts at the start of therapy may increase the risk of liver problems.

Severe skin and allergic reactions, including fatal cases have occurred with accompanying symptoms such as severe rash with fever, fatigue, muscle/joint pain, swelling of the face, hepatitis (liver inflammation), blood and kidney problems. If this occurs discontinue VIRAMUNE or VIRAMUNE XR and contact your doctor immediately.

In rare cases liver problems have led to liver failure and can lead to a liver transplant or death. Therefore, if you develop any of the following symptoms of liver problems stop taking VIRAMUNE or VIRAMUNE XR and call your doctor right away:

  • general ill feeling or “flu-like” symptoms
  • tiredness
  • nausea (feeling sick to your stomach)
  • lack of appetite
  • yellowing skin or whites of your eyes
  • dark urine (tea colored)
  • pale stools (bowel movements)
  • pain, ache, or sensitivity to touch on your right side below your ribs

Your doctor should check you and do blood tests often to check your liver function during the first 18 weeks of therapy. Checks for liver problems should continue regularly during treatment with VIRAMUNE or VIRAMUNE XR.

Skin Reactions:

Skin rash is the most common side effect of VIRAMUNE or VIRAMUNE XR. Most rashes occur in the first 6 weeks of treatment. In a small number of patients, rash can be serious and result in death. Therefore, if you develop a rash with any of the following symptoms, stop using VIRAMUNE or VIRAMUNE XR and call your doctor right away:

  • general ill feeling or “flu-like” symptoms
  • fever
  • muscle or joint aches
  • conjunctivitis (red or inflamed eyes, like “pinkeye”)
  • blisters
  • mouth sores
  • swelling of your face
  • tiredness
  • any symptoms of liver problems discussed above

If your doctor tells you to stop treatment with VIRAMUNE or VIRAMUNE XR because you have experienced the serious liver or skin reactions described above, never take VIRAMUNE or VIRAMUNE XR again.

These are not all the side effects of VIRAMUNE or VIRAMUNE XR. Tell your doctor if you have any side effects from VIRAMUNE or VIRAMUNE XR.

BEFORE you use VIRAMUNE or VIRAMUNE XR talk to your doctor or pharmacist:

  • If you have or have had any diseases of the liver particularly hepatitis B or C infection;
  • If you are pregnant or intend to become pregnant;
  • If you are a breast-feeding mother. It is recommended that HIV infected women not breastfeed, to avoid transmission of the virus to the infant;
  • If you are taking any medications, including prescription, non-prescription, herbal or homeopathic remedies;
  • If you have any allergies to foods or drugs;
  • If you are undergoing dialysis.

Side Effects

VIRAMUNE or VIRAMUNE XR can cause serious liver damage and skin reactions that can cause death. Any patients can experience such side effects, but some patients are more at risk than others.

Other common side effects of VIRAMUNE or VIRAMUNE XR include nausea, fatigue, fever, headache, vomiting, diarrhea, abdominal pain, skin rash and itching, myalgia (muscle pain) and arthralgia (joint pain). This list of side effects is not complete. Ask your doctor or pharmacist for more information.

Abnormal liver function test results, decrease in red blood cells or white blood cells called granulocytes, decrease in blood phosphorus, increase in blood pressure and hypersensitivity including severe allergic reaction with facial swelling may also occur.

If you feel unwell in any other way or have any symptoms that you do not understand, you should contact your doctor immediately.

Sleepiness can occur. Do not drive or operate machinery if you become drowsy.

Always tell your doctor or pharmacist about any undesirable effects you experience after taking VIRAMUNE or VIRAMUNE XR, even those not mentioned above.

Changes in body fat have been seen in some patients taking anti-retroviral therapy. These changes may include increased amount of fat in the upper back and neck (“buffalo hump”), breast, and around the trunk. Loss of fat from the legs, arms and face may also happen. The cause and long term health effects of these conditions are not known at this time.

Occasionally, the inactive ingredients of VIRAMUNE XR extended release tablets may be eliminated in the stool as a soft hydrated mass that looks like a whole tablet. There is no cause for alarm.

Consult your doctor immediately if you experience any symptoms as listed above, or any symptoms that you do not understand.

This is not a complete list of side effects. For any unexpected effects while taking VIRAMUNE or VIRAMUNE XR, contact your doctor or pharmacist.

Interactions with this medication

Drugs that may interact with VIRAMUNE or VIRAMUNE XR include:

VIRAMUNE or VIRAMUNE XR may change the effect of other medicines, and other medicines can change the effect of VIRAMUNE or VIRAMUNE XR. Tell your doctors and pharmacists about all medicines you take, including non-prescription medicines, vitamins and herbal supplements.

Do not take ketoconazole, rifampin, efavirenz, delavirdine, etravirine, rilpivirine, elvitegravir (in combination with cobicistat), or boceprevir; with VIRAMUNE or VIRAMUNE XR.

Tell your doctor if you take clarithromycin, fluconazole, methadone, rifabutin, indinavir, lopinavir/ritonavir combination, saquinavir or itraconazole.

VIRAMUNE or VIRAMUNE XR may not be right for you, or you may need careful monitoring.

You should be aware that VIRAMUNE or VIRAMUNE XR may change the effectiveness of oral contraceptives. Therefore oral contraceptives and other hormonal methods of birth control should not be used as a method of contraception in women taking VIRAMUNE or VIRAMUNE XR; other methods (barrier) must be used.

Proper Use of this medication

Usual dose:

Adult:

Follow the directions exactly as given to you by your doctor or pharmacist regarding the amount and frequency of dosing. The label will usually tell you this information as well. If you are not sure about dosing, ask your doctor or pharmacist.

VIRAMUNE Immediate Release Tablets:

As a general guide, swallow one tablet (200 mg) once a day for the first 14 days (this lead-in period should be used because it has been found to lessen the frequency of rash) followed by one 200 mg tablet twice daily as part of a multi-drug treatment program. VIRAMUNE immediate release tablets can be taken with or without food.

VIRAMUNE XR Extended Release Tablets:

Swallow one 200 mg tablet of VIRAMUNE immediate release once daily for the first 14 days to lessen the frequency of rash followed by one 400 mg tablet of VIRAMUNE XR extended release once daily. The VIRAMUNE XR extended release tablets should not be broken or chewed. VIRAMUNE XR extended release tablets can be taken with or without food.

It is important to strictly follow the once daily dose for the first 14 days. Do not start taking the 200 mg VIRAMUNE twice daily or the 400 mg VIRAMUNE XR once daily if you have any symptoms of liver problems or skin rash. The manufacturer's recommended dosage and monitoring for the other administered anti-retroviral drugs should be followed.

Patients Switching to VIRAMUNE XR Extended Release Tablets:

Patients already on a regimen of VIRAMUNE immediate release 200 mg twice daily in combination with other antiretroviral agents can be switched to VIRAMUNE XR extended release 400 mg once daily in combination with other antiretroviral agents without a lead-in period of VIRAMUNE immediate release.

Overdose:

In case of drug overdosage, contact a healthcare practitioner (e.g. doctor), hospital emergency department or regional Poison Control Centre, even if there are no symptoms.

Missed Dose:

If you miss a dose: If you forget to take your medicine, take it as soon as you remember. Then continue as before; do not double your next dosage.

If it is almost time for your next dose, do not take the missed dose. Instead, follow your regular dosing schedule by taking the next dose at its regular time.

If you stop taking VIRAMUNE or VIRAMUNE XR for more than 7 days, ask your doctor how much to take before you start taking it again. You may need to start with once-a-day 200 mg VIRAMUNE tablet dosing.

Avoid doing things that can spread HIV infection, as VIRAMUNE or VIRAMUNE XR does not stop you from passing HIV infection to others. Do not share needles, other injection equipment or personal items that can have blood or body fluids on them, like toothbrushes and razor blades. Always practice safe sex by using a latex or polyurethane condom to lower the chance of sexual contact with semen, vaginal secretions, or blood.

This medicine is for you. Never give it to someone else, as it may harm them even if their symptoms are the same as yours.

Take your medications exactly as prescribed by your doctor. Do not change the dose without consulting your doctor.

Do not take any other medication including prescription, non prescription, herbal or homeopathic remedies without your doctor's advice. Also, inform any other doctor, dentist or pharmacist you consult that you are taking this medication.

Keep out of reach of children.

If you have any other questions about VIRAMUNE or VIRAMUNE XR, contact your doctor or pharmacist.

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Viread (Tenofovir Disoproxil Fumarate)

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Viread (Tenofovir Disoproxil Fumarate) Dosage and Side Effects

VIREAD is always used in combination with other anti-HIV medicines to treat people with HIV infection. VIREAD is also used to treat chronic hepatitis B (an infection with hepatic B virus [HBV]) in adults age 18 years and older.

Warnings and Precautions

Serious Warnings and Precautions

  • The most serious possible side effect is harm to the kidneys, including damage to kidney cells, kidney tissue inflammation and kidney failure. Your doctor may monitor your kidney function before beginning and while receiving VIREAD. Some patients treated with tenofovir disoproxil fumarate (a component of VIREAD) have had kidney problems. Your doctor may need to perform additional blood tests if you have had kidney problems in the past or need to take another drug that can cause kidney problems.
  • If you have Hepatitis B Virus infection or if you have HIV and HBV infection together, “flare-ups” of Hepatitis B Virus infection, in which the disease suddenly returns in a worse way than before, can occur if you stop taking VIREAD. Do not stop taking VIREAD without your doctor's advice. If you stop taking VIREAD, tell your doctor immediately about any new, unusual or worsening symptoms that you notice after stopping treatment. After you stop taking VIREAD, your doctor will still need to check your health and take blood tests to check your liver for several months.
  • The class of medicines to which VIREAD belong (NRTIs) can cause a condition called lactic acidosis (build up of acid in the blood). The symptoms that may be signs of lactic acidosis include: feeling very weak, tired or uncomfortable, unusual or unexpected stomach discomfort, feeling cold, feeling dizzy or lightheaded, suddenly developing a slow or irregular heart beat. This rare but serious side effect has occasionally been fatal.
  • Severe liver problems can happen in people who take VIREAD or similar medicines. You may develop an enlarged liver (hepatomegaly) or a fatty liver (steatosis). Non-specific symptoms such as yellowing of the skin and eyes, nausea, vomiting, and stomach pain might indicate the development of liver problems.
  • Lactic acidosis or severe liver problems occur more often in women, particularly if they are very overweight. You should consult your doctor immediately if such symptoms occur while you are receiving VIREAD. If you notice these symptoms, stop taking VIREAD and consult a doctor immediately.
  • Tenofovir disoproxil fumarate caused harm to the bones of animals. Tenofovir disoproxil fumarate reduced bone density in humans. If you notice bone pain, suffer a bone fracture, or other bone problem, consult your doctor. If you have bone problems, you may wish to discuss calcium and/or vitamin D supplements with your doctors.
  • Changes in body fat have been seen in some patients taking antiretroviral therapy for the treatment of HIV infection. These changes may include increased amounts of fat in the upper back and neck (“buffalo hump”), breast, and around the trunk. Loss of fat from the legs, arms and face may also happen. The cause and long term health effects of these conditions are not known at this time.
  • Do not take VIREAD if you are already taking TRUVADA, ATRIPLA, COMPLERA or STRIBILD because VIREAD is one of the active ingredients in these products.
  • Do not take VIREAD if you have not already discontinued treatment with HEPSERA.

BEFORE you use VIREAD talk to your doctor or pharmacist if:

  • You are pregnant, planning to become pregnant: Pregnant mothers should not take VIREAD unless specifically directed by the doctor.
  • You are breastfeeding or planning to breastfeed: Do not breastfeed if you are taking VIREAD. Tenofovir passes to your baby in your breast milk. You should not breastfeed because of the risk of passing HIV or HBV to your baby. Talk to your doctor about the best way to feed your baby.
  • You have other medical conditions: Let your doctor know if you have other medical conditions, especially hepatitis (inflammation of the liver), pancreatitis (inflammation of the pancreas), bone and kidney problems.
  • You have HIV Infection.
  • You are taking other medicines: Some medicines can interact when taken together, including prescription and non-prescription medicines and dietary supplements.

Side Effects

The most common side effects of VIREAD are:

  • Diarrhea
  • Nausea
  • Vomiting
  • Dizziness

Other side effects include:

  • Flatulence (intestinal gas)
  • Allergic reaction, including angioedema (swelling of the blood vessels), with symptoms such as skin rash, redness, swelling of the hands, legs, feet, face, lips, tongue or throat) with difficulty in breathing
  • Stomach pain
  • Weakness
  • Inflammation of the pancreas
  • Shortness of breath
  • Headache
  • Rash

Changes in your immune system (Immune Reconstitution Syndrome) can happen when you start taking HIV medicines. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time, or you could develop an autoimmune disease in which your immune system reacts against your own body (e.g. Grave's disease (which affects the thyroid gland), Guillain-Barre syndrome (which affects the nervous system) or polymyositis (which affects the muscles) and it may develop at any time, sometimes months later after the start of HIV therapy). Sometimes symptoms can be severe, so if you develop high temperature (fever), joint or muscle pain, redness, rash, swelling or fatigue, or any new symptoms, contact your doctor right away.

Interactions with this medication

Drugs that contain didanosine (Videx, Videx EC). Tenofovir disoproxil fumarate (VIREAD) may increase the amount of Videx in your blood. You may need to be followed more carefully if you are taking VIREAD and Videx together. Also, the dose of didanosine may need to be reduced.

Reyataz (atazanavir sulfate), Kaletra (lopinavir/ritonavir), Prezista (darunavir) or HARVONI (ledipasvir/sofosbuvir) may increase the amount of tenofovir disoproxil fumarate (VIREAD) in your blood, which could result in more side effects. You may need to be followed more carefully if you are taking VIREAD together with Reyataz, Kaletra, Prezista or HARVONI. VIREAD may decrease the amount of Reyataz in your blood. If you are taking VIREAD and Reyataz together, you should also be taking Norvir (ritonavir).

Proper Use of this medication

Stay under a doctor's care when taking VIREAD. Do not change your treatment or stop treatment without first talking with your doctor.

Carefully follow the directions and dosing schedule prescribed by your doctor.

When your VIREAD supply starts to run low, see your doctor or pharmacist for a refill. This is very important because the amount of virus in your blood may increase if the medicine is stopped for even a short time. The virus may develop resistance to VIREAD and become harder to treat.

If you are taking VIREAD to treat your HIV or if you have HIV and HBV coinfection and are taking VIREAD, always take VIREAD in combination with other anti-HIV medicines. VIREAD and other products like VIREAD may be less likely to work in the future if you are not taking VIREAD with other anti-HIV medicines because you may develop resistance to those medicines.

If you have HBV only (without HIV), VIREAD can be prescribed as a single drug treatment for HBV.

Talk to your doctor about taking an HIV test before you start treatment with VIREAD for chronic hepatitis B.

Only take medicine that has been prescribed specifically for you. Do not give VIREAD to others or take medicine prescribed for someone else.

Usual adult dose:

  • The usual dose of VIREAD is one 300 mg tablet orally (by mouth) once a day.
  • VIREAD may be taken with or without a meal.

Usual adolescent (12 years of age and older) dose for HIV infection:

  • Body weight ≥35 kg (≥77 lb): Take one 300 mg VIREAD tablet once daily orally.
  • VIREAD may be taken with or without a meal.

Overdose:

In case of drug overdose, contact your healthcare practitioner (e.g. doctor), hospital emergency department or regional poison care centre, even if there are no symptoms.

Missed dose:

  • If you miss a dose of VIREAD, take it as soon as possible and then take your next scheduled dose at its regular time.
  • Do not double the next dose.

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Bromday (Bromfenac Sodium)

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Bromday (Bromfenac Sodium) Product Information

Bromday is a medicine that is prescribed for treatment of pain and swelling due to cataract surgery. It is a non-steroidal anti-inflammatory drug (NSAID).

It is good to tell your doctor about your asthma, arthritis, diabetes, dry eye syndrome or any bleeding disorder you had in your life. This can help them make a firm decision about you taking Bromday.

Check and Compare Bromday Cost with PricePro Pharmacy

At PricePro Pharmacy, we carry Bromday 0.09% as a product of the United Kingdom. The active ingredient of this eye drop is Bromfenac Sodium. The lowest price for this product starts at $178 for one 5ml bottle and $534 for three 5ml bottles.

This product is manufactured by Bausch & Lomb.  It take an estimated 7-10 business days for your Bromday order to arrive to USA.

Generic Bromfenac Eye Drops Available at Lower Price

Generic Bromday known as Bromfenac 0.09% is also available as a product of India. This medication is manufactured by Ajanta Pharma and the lowest price is $47 for 5ml bottle and $138 for three 5ml bottles.

A prescription is required to process your order and it can be submitted by mail, email, fax, or uploaded directly on the website. If you require further assistance you can contact our customer support at 1-855-776-0079.

Bromday (Bromfenac) Medication Information

Uses

Bromday is a nonsteroidal anti-inflammatory drug (NSAID) indicated for the treatment of postoperative inflammation and reduction of ocular pain in patients who have undergone cataract extraction

Dosage

The ophthalmic solution is 0.09% 

Side Effects

The most common side effects of Bromday include:

  • Conjunctival hyperemia
  • Eye irritation
  • Abnormal sensation in eye

Speak with your doctor or pharmacist for a full list of side effects that applies to you.

Precautions

Bromday is a nonsteroidal anti-inflammatory drug (NSAID) indicated for the treatment of postoperative inflammation and reduction of ocular pain in patients who have undergone cataract extraction.

All topical nonsteroidal anti-inflammatory drugs (NSAIDs) may slow or delay healing. Topical corticosteroids are also known to slow or delay healing. Concomitant use of topical NSAIDs and topical steroids may increase the potential for healing problems.

With some NSAIDs, there exists the potential for increased bleeding time due to interference with platelet aggregation. There have been reports that ocularly applied NSAIDs may cause increased bleeding of ocular tissues (including hyphemas) in conjunction with ocular surgery.

Use of topical NSAIDs may result in keratitis. In some susceptible patients, continued use of topical NSAIDs may result in epithelial breakdown, corneal thinning, corneal erosion, corneal ulceration or corneal perforation. These events may be sight threatening. Patients with evidence of corneal epithelial breakdown should immediately discontinue use of topical NSAIDs and should be closely monitored for corneal health.

Interactions

Some of the common drug interactions with Bromday:

  • Corticosteroids
  • Prostaglandins 

Speak with your doctor or pharmacist for more information. 

Storage

Store at controlled room temperature (59º–77ºF). 

Pharmacist Tips

  • Possibility that slow or delayed healing may occur while using NSAIDs.
  • Do not touch the dropper tip to any surface, as this may contaminate the contents.

Bromfenac FAQs

How do I use Bromday drops?

Bromday ophthalmic solution should be applied to the affected eye(s) once daily beginning 1 day prior to cataract surgery, continued on the day of surgery, and through the first 14 days of the postoperative period.

 

Can I take this if I am pregnant?

There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

 

Can I take this while breastfeeding?

Caution should be exercised when Bromday is administered to a nursing woman.

 

Can I wear contacts while using Bromday?

Contact lenses should not be worn during the use of this product.

 

What should I do if I have multiple drops to instill?

If more than one topical ophthalmic medication is being used, the medicines should be administered at least 5 minutes apart.

 

What is Bromday used for?

Bromday is indicated for the treatment of postoperative inflammation and reduction of ocular pain in patients who have undergone cataract surgery.

 

Related Drugs

Reference:

Bromday {package insert}. Tampa, FL: Bausch & Lomb Inc.; 2010. 

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021664s013lbl.pdf

PharmD Medical Writer

Author: Dr. Larisa Roybal, PharmD

Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.

Breo Ellipta (Fluticasone Furoate/Vilanterol)

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Breo Coupon

Breo Ellipta Rx Coupon

Breo Ellipta Inhaler from Canada

Save Extra $20 with Breo Coupon Code BRE20

Did you know we offer up to 80% cost savings compared to your local pharmacy? Plus we offer Rx coupons for bigger discounts.

Enter Breo coupon code BRE20 at checkout. Apply this discount for additional savings on your prescription cost.

You can apply this pharmacy coupon code to either dosage. Why pay more when you don't have to, let the savings begin.

*Coupon codes cannot be combined and are for one-time use only.

Order Canadian Pharmacy Breo Ellipta Now and Save with Our Breo Coupon

As a steroid and bronchodilator, Breo Ellipta (Fluticasone Furoate/Vilanterol) is a prescription drug that helps to prevent inflammation and open up the airways by relaxing the muscles to improve a patient’s breathing.

The medication is often given to adults with COPD or asthma to reduce symptoms, and to help prevent asthma attacks and bronchospasm.

An order can be placed online by navigating through our checkout process or by calling 1-855-776-0079 to speak with a customer service rep today.

Please note a prescription is required to process your order. The Rx can be emailed, faxed, uploaded, or we can even reach out to your doctor.

Click on the dosage box above to start the process and be sure to apply Breo coupon 2021 code BRE20 at checkout.

There are two active medicinal ingredients in Breo Ellipta, fluticasone furoate and vilanterol. Fluticasone furoate works to decrease inflammation in the airways as it classified as an inhaled corticosteroid. Vilanterol works to relax and expand the airways, making it easier to breathe which prevents episodes of wheezing and shortness of breath. It is important to note that this inhaler help manage symptoms of COPD and asthma but it is not a cure for the condition. 

The Breo Inhaler: An Overview

Breo is manufactured by GlaxoSmithKline (GSK) and is also marketed in the United Kingdom as Relvar Ellipta. Currently there is no Breo Ellipta generic on the market at this time. Once available we will be able to offer it as cheaper Breo cost alternative.

The dosage forms available are: Breo Ellipta 100mcg/25mcg equivalent to (92mcg/22mcg) and Breo Ellipta 200mcg/25mcg equivalent to 184mcg/22mcg. The medication is a dry powder that is inhaled orally and there are 30 doses within each inhaler. A typical 3-month supply is 90 doses which is 3 inhalers.

The estimated shipping time for you order would be 7 to 10 business days. Once you order ships from our certified Canadian pharmacy or partner UK pharmacy you will be notified with a shipping email. The tracking details will be available if tracked shipping is selected.

There is a standard $9.95 shipping charge applied to each order.

Save Big on Your Breo Ellipta Cost

When placing an order to buy Breo Ellipta inhalers online, a prescription must be sent in to process and complete the order. If you need any help with placing your first order then be sure to check out helpful guide on how to order from an online Canadian Pharmacy.

We are proud to offer up to 80% savings on Breo Ellipta cost, just simply click on "CHECK PRICES" to instantly find quantity and pricing details on this medication.

Lower the cost with our Breo coupon available on our Rx coupon page, the prices we offer are significantly less than your local US pharmacy.

We also have friendly refill reminder service that will kindly update you by phone or email as to preferred time to re-order based on your on-hand supply and estimated shipping times.

Let PricePro Pharmacy be your preferred source for discount prescription drugs online.

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Breo Ellipta Dosage

The following dosages are available to order:

  • Breo Ellipta 100mcg/25mcg
  • Breo Ellipta 200mcg/25mcg

The Breo Ellipta inhaler is manufactured by GlaxoSmithKline and available in a pack size of 30 doses per inhaler.

Breo Ellipta is also marketed under the name Relvar Ellipta in the United Kingdom and Turkey.

 

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Breo Inhaler Cost

The low cost of Breo inhaler at PricePro Pharmacy is:

  • $85 for one inhaler (30 doses)
  • As low as $2.40 per dose

To further save on Breo Ellipta price it is better to order a 3-month supply of medication than 1-month supply. The prices are cheaper when order a larger supply.

Rx coupons

Breo Ellipta Coupon

Apply Breo inhaler coupon code BRE20 for instant $20 discount at checkout.

This coupon for Breo can be used for any dosage or product source.

Lower cost generic drug alternative

Breo Ellipta Generic

There currently is no generic for Breo Ellipta available at this time. Once a lower cost alternative is available we will update our catalogue and make it available for ordering.

Generic drugs are typically 40-60% cheaper than the brand version.

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Shipping Times

The estimated shipping times depend on the medication ordered:

  • Product of Canada or UK - 7 to 12 business days
  • Product of Turkey - 10 to 18 business days

There is a standard shipping charge of $9.95 applied to each order.

Once you medication ships you will receive an email alert with the applicable tracking information.

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Prescription Refill Online

We offer a free refill reminder service that will kindly remind you by phone or email on the optimal time to place your re-order based on your prescription history and estimated shipping times.

Your prescription can also be refilled by signing into your online pharmacy account or by calling 1-855-776-0079.

Breo Ellipta (Fluticasone Furoate/Vilanterol) Medication Information

Uses

Breo Ellipta contains two different medications, called fluticasone furoate and vilanterol. It is approved for the maintenance treatment of the inflammatory lung conditions asthma and chronic obstructive pulmonary disease (COPD).

Breo Ellipta controls symptoms like cough, wheezing, and shortness of breath. It is a daily medication that reduces the need for rescue inhalers like albuterol.

Breo Ellipta contains an inhaled corticosteroid (ICS) and a long-acting beta-agonist (LABA). The ICS decreases inflammation in the lungs, which relaxes the airways and makes it easier to breathe. The LABA relaxes the smooth muscles of the lungs and opens the airways.

Dosage

Breo Ellipta inhalers come in two different sizes, including fluticasone furoate/vilanterol 200 mcg/25 mcg and 100 mcg/25 mcg. Your doctor will prescribe one of these sizes.

Inhale the contents of one blister pack by mouth once daily. Use Breo Ellipta every day, even if you don’t have symptoms.

Side Effects

Common side effects of Breo Ellipta include:

  • Arthralgia
  • Back pain
  • Bronchitis
  • Cough
  • Dysphonia Cough
  • Headache
  • Hypertension
  • Influenza
  • Nasopharyngitis
  • Oral candidiasis
  • Oropharyngeal pain
  • Pharyngitis
  • Pneumonia
  • Pyrexia
  • Sinusitis
  • Upper respiratory tract infection

Precautions

Breo Ellipta is not a rescue inhaler and should not be used for an “attack” or acute bronchospasm. Bronchospasms should be treated with a short-acting beta-agonist like albuterol.  

Breo Ellipta inhalation contains milk proteins, so do not use if you have hypersensitivity to milk or whey.

Rinse the mouth with water after each use and spit the water out without swallowing. Rinsing will help prevent the development of oral thrush.

People with COPD are at an increased risk of pneumonia when they take Breo Ellipta.

Tell your doctor if you have a latent infection, including tuberculosis, ocular herpes simplex, or other infections.

In some rare cases, Breo Ellipta can cause bronchospasm. If this happens, stop taking it and tell your doctor.

Tell your doctor if you have a history of glaucoma.

Interactions

Drug interactions are rare with Breo Ellipta because it does not absorb into the bloodstream. However, interactions can still happen if you are taking the following medications:

  • Beta-blockers
  • Clarithromycin
  • Diltiazem
  • Diuretics
  • Erythromycin
  • Goldenseal
  • Grapefruit
  • Itraconazole
  • Ketoconazole
  • Monoamine oxidase inhibitors
  • Ritonavir
  • Tricyclic antidepressants
  • Verapamil

Storage

Store Breo Ellipta at room temperature between 68°F and 77°F (20°C and 25°C).

Pharmacist Tips

  • After inhalation, hold your breath for at least 3 to 4 seconds to let the medication absorb into the lungs
  • To “prime” the inhaler, open the cover until it clicks. This loads a dose of medication that is ready for inhalation.
  • Only open the cover when you are ready to inhale your dose. If you close the cover without using the dose, it will be lost.

Breo Ellipta FAQs

When should I remove the inhaler from the sealed tray?

Breo Ellipta comes packaged in a sealed tray with a desiccant to prevent moisture from getting into the inhaler. Once you take it out of the tray, it should be discarded after six weeks.

 

How many doses are in each inhaler?

Each inhaler has 30 inhalations, and you can tell how many are left by reading the dosage counter.

 

How long does it take for this to work?

You should notice the effects of Breo Ellipta within 1-2 weeks of daily use.

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References

  1. Breo Ellipta [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2019.

Medication Review by a Clinical Pharmacist - PharmD

Author: Dr. Conor Sheehy, PharmD, BCPS

Dr. Sheehy is a board-certified pharmacotherapy specialist. He has worked in multiple practice settings, including retail and hospital pharmacies, and in medical clinics.  He specializes in anticoagulation, psychiatric medications, and diabetes medications. He strives to empower his patients to understand their medications and improve their overall medical care.

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Biltricide (Praziquantel)

Author , posted on June 16, 2017

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Biltricide

Praziquantel

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Biltricide (Praziquantel) Product Information

Biltricide is a prescription medication for treating infections triggered by liver flukes and schistosomes. It is therefore recommended for treatment of bilharziasis, snail fever and schistosomiasis. Also known as Praziquantel, Biltricide can be indicated for treating any other worm infections— except pinworms and roundworms infections.

Belonging to a group of medicines called anthelmintics, Biltricide causes powerful spasms and paralysis of some worm’s muscles. Additionally, it causes some other types of worms to be passed in the stool. Still, some worms are totally damaged in the intestines and cannot be spotted in the stool.

Order Biltricide 600mg Online

Biltricide is manufactured by Bayer and we have it available in one strength: 600 mg.  The active ingredient is called Praziquantel. The cost of this product starts at $71 for six tablets and up to $213 for eighteen tablets.

This medication would be dispensed from one of our Canadian pharmacies and the estimated shipping time would be 7-10 business days to the United States.

There is a standard shipping fee of $9.95 per order.

Please note a Biltricide prescription is required to process your online order. You can submit the prescription by fax, email, or upload directly on our website. If you need assistance with ordering you can call our customer support line at 1-855-776-0079 or view the ordering guide online.

Dosage

The correct amount to take will be based on whether you are an adult or a child and the infection you are trying to treat. If it is schistosomiasis, the right dose will depend on your body weight. The dose is normally 20 mg per kilogram of body weight and is taken three times per day.  This medicine is only taken for one day and doses should be spaced out. Ensure that your doses are no less than four hours apart and no more than six hours apart. If dealing with a child who is younger than four years old, let the correct dosage be determined by their doctor

Ensure that you take your medicine with eight ounces of water with your meal. It is okay to break your Biltricide tablet to ensure that you get the correct dose. Don’t chew it as a whole or part of it though, as it is bitter and might cause vomiting. If being taken by a child who cannot swallow it, then you should crush it and mix with a liquid or some watery food.

Side Effects

This medicine can cause some severe and mild side effects. The latter is common and most people are able to bear it. The following are the most prevalent side effects:

  • A general feeling of sickness
  • Stomach problems and nausea
  • Fever
  • Headache
  • Dizziness
  • Skin rash

Precautions

Biltricide should be taken with care, just like any other medicine for treating worms. Hence, take the following precautions when taking it:

  • Avoid taking Biltricide if you are allergic to it
  • If you have taken rifampin in the past one month, don’t take Biltricide
  • Avoid taking this medicine if you are suffering from a parasitic infection in the eyes
  • Let your doctor know if you suffer from nodules or lumps under the skin
  • Inform your physician about your liver disease, heart issues, epilepsy or seizures
  • If you are pregnant or lactating, let your health expert know
  • Don’t drive or perform any dangerous activity after taking this medicine
  • Don’t eat grapefruits, drink grapefruit juice or consume another grapefruit product

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