Zomig Rapimelt (Zolmitriptan)

Generic equivalent: Zolmitriptan ODT

    Zomig (Zolmitriptan) Dosage and Side Effects

    ZOMIG is a headache medicine that narrows blood vessels around the brain. ZOMIG also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.  ZOMIG will only treat a headache that has already begun.

    Warnings and Precautions

    BEFORE you use ZOMIG/ZOMIG RAPIMELT talk to your doctor or pharmacist if the answer to any of the following questions is YES, or if you do not know the answer:

    • Are you pregnant, think you might be pregnant, or trying to become pregnant? Are you using inadequate contraception? Are you breastfeeding?

    • Do you or have you ever experienced any pain or tightness in the chest, (which may or may not spread to your neck, jaw, or upper arm), shortness of breath, or irregular heart beats (including a fast heart beat called Wolff-Parkinson-White syndrome)? Do you have angina? Have you ever had heart or blood vessel disease? Do you have a history of cerebral bleeding? Have you had a heart attack or stroke?

    • Do you have risk factors for heart disease, such as: high blood pressure, high cholesterol, smoking, obesity, diabetes, or strong family history of heart disease?

    • Do you have a condition called phenylketonuria (a specific blood disorder)?

    • Do you have rare hereditary problems of galactose intolerance?

    • Are you post-menopausal, or a male over 40?

    • Do you have high blood pressure?

    • Have you ever had to stop taking this or any other medication because of an allergy or other problems?

    • Are you taking any other migraine 5-HT1 agonist medications such as sumatriptan succinate, naratriptan hydrochloride, rizatriptan benzoate, almotriptan malate or migraine medications containing ergotamine, dihydroergotamine, or methysergide?

    • Are you taking any medications for depression such as selective serotonin reuptake inhibitors (SSRI's), for example, fluoxetine hydrochloride, sertraline hydrochloride, fluvoxamine maleate, paroxetine hydrochloride, etc., or serotonin norepinephrine reuptake inhibitors (SNRIs), for example, venlafaxine hydrochloride, or monoamine oxidase inhibitors (MAOIs), for example, phenelzine sulfate, tranylcypromine sulfate or moclobemide?

    • Have you ever experienced numbness on one side of your body when you have a headache?

    • Have you ever had epilepsy or seizures?

    • Have you ever had liver disease?

    • Are you over 65 years of age?

    • Is this headache different from your usual migraine attacks?

    • Are you taking cimetidine (for treatment of indigestion or stomach ulcers) or a member of the quinolone family of antibiotics (for example ciprofloxacin)?

    If you use ZOMIG/ZOMIG RAPIMELT too often, it may make your headaches worse. If this happens, your doctor may tell you to stop taking ZOMIG/ZOMIG RAPIMELT.

    ZOMIG tablets contain lactose which is a type of sugar. If you have been told by your doctor that you cannot tolerate or digest milk or some sugars, talk to your doctor before taking this medicine.

    Use of ZOMIG/ZOMIG RAPIMELT during pregnancy:

    Do not use ZOMIG or ZOMIG RAPIMELT if you are pregnant, think you might be pregnant, are trying to become pregnant or are using inadequate contraception, unless you have discussed this with your doctor.

    Side Effects

    Although the vast majority of ZOMIG and ZOMIG RAPIMELT users have not experienced any significant problems, you should be aware that the following side effects may occur.

    Commonly reported side effects of ZOMIG and ZOMIG RAPIMELT are:

    • feeling sick

    • vomiting

    • dizziness

    • tiredness

    • weakness

    ZOMIG may commonly cause drowsiness. Do not drive or operate machinery until you are sure that you are not drowsy.

    Other common side effects include:

    • muscle aches and pains

    • difficulty swallowing

    • dry mouth

    • headache

    • stomach pain

    Uncommon side effects include:

    • increase in the production of urine or in the frequency of urination

    Tell your doctor of these symptoms at your next visit.

    Migraineurs may be at risk of certain cerebrovascular events such as cerebral bleeding and stroke. In very rare cases, as with other drugs of this type, such diseases have been reported in association with the use of zolmitriptan.

    In very rare cases, as with other drugs of this type (5HT1 agonists), the following side effects have been reported:

    • spasm of the blood vessels of the heart

    • spasm of the blood vessels of the Gastro-Intestinal tract and spleen with possible infarctions

    For any unexpected effects while taking ZOMIG/ZOMIG RAPIMELT, contact your doctor or pharmacist.

    Interactions with this medication

    Tell your doctor or pharmacist about any other drugs you take, including:

    • other 5-HT1 agonist migraine drugs (sumatriptan succinate, naratriptan hydrochloride, rizatriptan benzoate, almotriptan malate) or migraine drugs that contain ergotamine, dihydroergotamine, methysergide.

    • drugs for depression such as selective serotonin reuptake inhibitors (SSRI's), for example, fluoxetine hydrochloride, sertraline hydrochloride, fluvoxamine maleate, paroxetine hydrochloride, etc., or serotonin norepinephrine reuptake inhibitors (SNRIs), for example, venlafaxine hydrochloride, or monoamine oxidase inhibitors (MAOIs), for example, phenelzine sulfate, tranylcypromine sulfate or moclobemide.

    • drugs used to treat upset stomach or stomach ulcers (cimetidine).

    • antibiotics from the quinolone family (for example ciprofloxacin).

    Please inform your doctor or pharmacist if you are taking or have recently taken any other medicines, even those that can be bought without a prescription.

    Proper Use of this medication

    Usual dose:

    Adults:

    The usual dosage is 2.5 mg, or lower if recommended by your doctor. A lower dose can be obtained by manually breaking a conventional tablet in half. The ZOMIG RAPIMELT 2.5 mg orally dispersible tablets cannot be broken in half. The dose should be taken as soon as your migraine appears, but it may be taken at any time during your migraine headache. Swallow your dose with water.

    For ZOMIG RAPIMELT orally dispersible tablets, the blister pack should be peeled open as shown on the foil (tablets should not be pushed through the foil). The ZOMIG RAPIMELT tablet should be placed on the tongue, where it will dissolve with the saliva. Water is not needed for the dispersible tablet.

    A second dose may be taken if your headache returns, but not sooner than 2 hours following the first tablet. For any attack where you have no response to the first dose, do not take a second dose without first consulting your doctor.

    Do not administer more than 10 mg in any 24 hour period.

    Overdose:

    If you have taken more medication than your doctor has instructed, contact either your doctor, hospital emergency department, or nearest poison control centre immediately.

    Other related products

    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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