Janumet (Sitagliptin/Metformin)

(℞) Prescription Required

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Janumet 50mg/500mg

Product of Canada
Manufactured by: Merck Sharp & Dohme
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Janumet 50mg/500mg
Product of Canada
Manufactured by Merck Sharp & Dohme
Top Brand Choice
Top Generic Choice

Janumet 50mg/850mg

Product of Canada
Manufactured by: Merck Sharp & Dohme
*Product image for reference use only.
Select Quantity
Janumet 50mg/850mg
Product of Canada
Manufactured by Merck Sharp & Dohme
Top Brand Choice
Top Generic Choice

Janumet 50mg/1000mg

Product of Canada
Manufactured by: Merck Sharp & Dohme
*Product image for reference use only.
Select Quantity
Janumet 50mg/1000mg
Product of Canada
Manufactured by Merck Sharp & Dohme
Select your dosage

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Along with diet and exercise, the prescription drug Janumet (Sitagliptin/Metformin) is given to patients with Type 2 diabetes to improve blood sugar levels. 

On this page, you'll find information about this medication including Janumet dosage, side effects, and interactions. 

Save On Janumet (Sitagliptin/Metformin)

Are you looking to keep the Janumet price as low as possible? You're in the right place! You'll find the best prices on the Web through our online pharmacy.

Unfortunately, we do not offer a Janumet coupon at this time. However, we welcome you to get in touch and talk with our experts. We can help you find the best prices for your needs, and provide insightful guidance throughout.

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Janumet Medication

The following doses are available to order:

  • Janumet 50mg/1000mg
  • Janumet 50mg/500mg
  • Janumet 50mg/850mg

This medication is manufactured by Merck Sharp & Dohme. When you select your prescribed dosage you can view options available including prices.

The active medicinal ingredients are Sitagliptin and Metformin.

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Janumet Cost

At PricePro Pharmacy the low cost of Janumet 50mg/1000mg is:

  • $75.00 for 56 tablets
  • $0.98 per tablet for a 3-month supply

For more savings on Janumet price, it is better value to order a 90-day supply of medication compared to 30-day supply. Also there is no need find manufacturer coupons or worry about insurance coverage to these discounts.

Rx Coupons

Janumet Coupon

Currently we do not have a Janumet coupon code for additional discount. However, we love helping our patients save money so for those placing their first order there are special offers available.

New customer coupon codes can be applied at checkout as follows:

  • PRICE10 - Save $10 on your first order (minimum $50 order value)
  • PRICE20 - Save $20 on your first order (minimum $100 order value)

Please note that these pharmacy coupon codes are one-time use only for new customers and cannot be combined with other coupons/offers. Be sure to check our Rx coupons page for future updates.

Lower cost generic drug alternative

Janumet Generic

There currently is no generic for Janumet available at this time. Once a lower cost alternative is available we will update our catalogue and make it available for ordering.

Generic drugs are typically 40-60% cheaper than the brand version.

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Prescription Delivery Times

The estimated shipping time for your order is:

  • 7 to 10 business days (Product of Canada)
  • 7 to 12 business days (Product of United Kingdom)
  • 10-18 business days (Product of Australia or Turkey)

The standard shipping cost $9.95 for all orders.

For drugs ordered from Canada, we offer an Express shipping option. The shipping fee is $25 with an estimated delivery time of 3 to 5 business days.

Once you order ships from the licensed pharmacy you will receive an email notification with the applicable shipping details.


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Prescription Refill

We provide a refill reminder service where we give you an email or call you, reminding you of the right time to place a new order and taking into account delivery times.

You can access the details of your prescription and order history online. Even, to put a reorder online, just log in to your online user account and press the reorder button. If your prescription is valid, you don't need to submit a new one. If not, we will need a new prescription to complete your order.

Janumet (Metformin and Sitagliptin) Medication Information


Janumet is a prescription medication that treats diabetes mellitus type 2. It contains a combination of the drugs metformin and sitagliptin.

People with type 2 diabetes do not have enough insulin to meet their needs. People with this condition either do not produce enough insulin or their bodies are resistant to the effects of insulin. Without enough insulin, blood glucose is too high and can cause damage to the blood vessels.

Diabetes can damage small vessels (microvascular damage) and large vessels (macrovascular damage). In microvascular damage, the affected organs are the kidneys, the eyes, and the nerves. Macrovascular damage includes ischemic heart disease, peripheral vascular disease, and cerebral vascular disease.

The first ingredient in Janumet, metformin, works by decreasing the amount of glucose produced by the liver.

The second ingredient, sitagliptin, inhibits an enzyme called dipeptidyl peptidase IV (DPP-IV). DPP-IV breaks down enzymes that regulate insulin and blood sugar in people with diabetes.

Janumet should be used in addition to diet and exercise to manage type 2 diabetes mellitus. 


Janumet is available in the tablet sizes:

  • Sitagliptin/Metformin 50/500 mg
  • Sitagliptin/Metformin 50/1000 mg

Your doctor will determine the best dose of Janumet for you. It is taken twice daily.

The maximum dose of sitagliptin is 100 mg per day. The maximum dose of metformin is 1000 mg per day.

Side Effects

  • Abdominal pain
  • Diarrhea
  • Headache
  • Low blood sugar
  • Nausea
  • Upper respiratory tract infection
  • Vomiting


Metformin is known to cause a severe and sometimes life-threatening condition called lactic acidosis. The condition is rare, but the risk is increased in people who drink large amounts of alcohol, are older than 65, and those with liver problems.

Tell your doctor if you have a history of liver or kidney problems. Janumet should not be used in people with severe kidney dysfunction.

You may need to stop Janumet before invasive procedures or imaging procedures that require iodinated contrast imaging.

Tell your doctor if you have a history of heart failure or pancreatitis.

Long-term use of metformin increases the risk of vitamin B12 deficiency. Your doctor may do a lab test for this.


Tell your doctor or pharmacist if you are taking any of these medications:

  • Alcohol
  • Carbonic anhydrase inhibitors
  • Cimetidine
  • Dolutegravir
  • Insulin
  • Iodinated contrast agent
  • Ranolazine
  • Sulfonylureas
  • Vandetanib


Store Janumet at room temperature, 20-25°C (68-77°F).

Pharmacist Tips

  • Take Janumet with food to reduce the risk of stomach upset and diarrhea.
  • Familiarize yourself with the symptoms of low blood sugar (hypoglycemia) while you are taking anti-diabetic medications.
  • Do not split, crush, or chew Janumet. Swallow it whole with a full glass of water.

Janumet FAQs

Should Janumet be taken with or without food?

Take Janumet with food to lower the risk of stomach upset and diarrhea.


Can Janumet be used in people with type 1 diabetes?

No. Janumet can only be used for type 2 diabetes.


What if I miss a dose of Janumet?

Take the dose if it’s within six hours of your normal administration time. Do not double up.

Related Products


  1. Janumet [package insert]. Whitehouse Station, NJ: Merck; 2019.

Medication Review by a Clinical Pharmacist - PharmD

Author: Dr. Conor Sheehy, PharmD, BCPS

Dr. Sheehy is a board-certified pharmacotherapy specialist. He has worked in multiple practice settings, including retail and hospital pharmacies, and in medical clinics.  He specializes in anticoagulation, psychiatric medications, and diabetes medications. He strives to empower his patients to understand their medications and improve their overall medical care.

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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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