Yohimbine (Yohimbine Hcl)

Author , posted on June 15, 2017

Category:


Yohimbine

Yohimbine Hcl

Select Quantity:

Yohimbine Dosage and Side Effects

The bark of the West African yohimbe tree is rich in the alkaloid yohimbine, and both the crude bark and purified compound long have been hailed as aphrodisiacs. The bark has been smoked as a hallucinogen and has been used in traditional medicine to treat angina and hypertension.

Warnings and Precautions

Yohimbe may cause central nervous system stimulation and paralysis, and may precipitate psychoses in predisposed individuals.

Side Effects

This drug may cause severe hypotension, hypertension, abdominal distress, and weakness.

Interactions with this medication

None well documented.

Proper Use of this medication

Refer to manufacturer's recommendations.

Other related products

Votrient (Pazopanib)

Author , posted on June 15, 2017

Category:


Votrient

Pazopanib Hydrochloride

Select Quantity:

Votrient

Pazopanib Hydrochloride

Select Quantity:

Votrient

Pazopanib Hydrochloride

Select Quantity:

Pazopanib (Generic)

Pazopanib Hydrochloride

Select Quantity:
Select Quantity:

Votrient (Pazopanib) Dosage and Side Effects

VOTRIENT is used in the treatment of Metastatic kidney cancer (when cancer cells have spread from the kidney to other parts of the body).

Warnings and Precautions

Serious Warnings and Precautions

VOTRIENT should be prescribed and managed by a doctor experienced in the use of cancer drugs.

VOTRIENT is not recommended for patients with moderate or severe liver impairment (reduced function).

Serious side effects with the use of VOTRIENT may include the following:

  • Liver toxicity

  • High blood pressure

  • Effect on the electrical activity of the heart (QT/QTc prolongation)

  • Heart becomes less effective at pumping blood (cardiac dysfunction)

  • Blood clots (arterial thromboembolic or venous thrombotic events and thrombotic microangiopathy)

  • Bleeding

  • Gastrointestinal perforation (a hole that develops through the wall of the stomach, small intestine or large bowel) and fistula (an abnormal connection between parts of the digestive tract)

  • Reversible swelling in the rear part of the brain that can be associated with high blood pressure and can lead to headache, loss of speech or vision, abnormal drowsiness, confusion and/or seizure (Posterior Reversible Encephalopathy Syndrome or Reversible Posterior Leukoencephalopathy Syndrome)

Safety and efficacy of VOTRIENT have not been established in children less than 18 years of age. VOTRIENT must not be used in children under two years of age.

BEFORE you use VOTRIENT talk to your doctor or pharmacist:

  • If you have or had heart disease, heart failure or heart attack

  • If you have or have had a heart rhythm disorder such as irregular heartbeat, prolongation of the QT interval or any risk factors for Torsade de Pointes (dangerous rapid fluttering of the heart) such as diabetes, low potassium, magnesium or calcium levels, or a history of low heart rate, fainting, or loss of consciousness

  • If you have high blood pressure

  • If you have liver disease

  • If you have problems with bleeding

  • If you have gastrointestinal problems

  • If you have or had a blood clot in a vein or in a lung

  • If you have had prior collapse of a lung

  • If you have a kidney problem

  • If you have thyroid problems

  • If you are going to have a surgical or dental procedure, or if you have had either recently

While you are taking VOTRIENT your doctor will take blood samples to check for any liver problems. You should report any signs or symptoms of liver injury including jaundice (yellowing of whites of eyes or skin), unusual darkening of the urine, anorexia (loss of appetite), nausea, fatigue, right upper abdominal discomfort and vomiting. Your doctor will also take urine samples to check for any kidney problems. You will also have your blood pressure checked. Your doctor will periodically record your electrocardiogram (ECG) to check your heart's electrical conduction.

Your doctor will also check on any recent surgical or dental procedures to see if you are healing properly.

Use a reliable method of contraception to avoid becoming pregnant while you’re taking VOTRIENT and for up to 8 weeks after you stop treatment with VOTRIENT. If you are pregnant or think you could be, talk to your doctor about the risks and benefits to you and your baby while taking VOTRIENT. Your doctor may recommend that you don't take VOTRIENT while you are pregnant.

Breastfeeding is not recommended during treatment with VOTRIENT. Ask your doctor for advice.

Side Effects

Like all medicines, VOTRIENT can cause side effects.

Very common side effects—these may affect more than 1 in 10 people:

  • diarrhea (which can be severe; e.g. with fever or 3 or more times a day)
  • feeling or being sick (nausea or vomiting)
  • loss of appetite
  • stomach pain or discomfort
  • high blood pressure
  • headache
  • loss of strength
  • lack of energy
  • weakness
  • changes in hair colour
  • weight loss
  • problems with taste
  • skin rash
  • a skin reaction or pain on the palms of the hands or soles of the feet (including tingling, numbness, pain, swelling or reddening)
  • dizziness
  • cough
  • shortness of breath
  • chest pain
  • swelling of hands, ankles or feet
  • muscle pain
  • pain in the bones, muscles, ligaments, joints and tendons
  • mouth sores
  • unusual hair loss or thinning
  • loss of skin pigment
  • slow heart rate

Very common side effect that may show up in your blood tests:

  • increase in some substances (enzymes) produced by the liver

Common side effects—these may affect up to 1 in 10 people:

  • temporary reduction in blood supply to the brain (mini-stroke)
  • reduction of blood supply to the heart (angina)
  • changes in the heart's electrical conduction (QT-prolongation) which may cause irregular heartbeat
  • heart attack
  • severe bleeding in the lung
  • under-active thyroid gland
  • abnormal liver function (which can be severe and may cause yellowing of the skin or the whites of the eyes (jaundice), unusual darkening of the urine, unusual tiredness, or right upper stomach area pain)
  • indigestion
  • flatulence
  • nosebleeds
  • dry skin
  • nail disorder
  • hoarseness
  • blurred vision
  • chills
  • urinary tract infection
  • blood in the urine
  • painful urination
  • sudden collapse of a lung
  • heart becomes less effective at pumping blood (cardiac dysfunction)
  • excessive sweating
  • atypical prickling or crawling sensations on the skin
  • sore mouth or mouth ulcers
  • blood clot in your body (you might feel chest pain, shortness of breath, leg pain, and swelling of the legs/feet). Such blood clots can break off and travel to your lungs which may be life-threatening or even fatal
  • muscle spasms

Common side effects that may show up in your blood or urine tests:

  • a decrease in the number of cells involved in blood clotting (thrombocytopenia)
  • low white blood cell count (neutropenia, leucopenia, lymphopenia)
  • protein in urine
  • increase in bilirubin (a substance produced by the liver)
  • decrease in albumin (a protein found in the blood)
  • increase in lipase (an enzyme from the pancreas)
  • increased potassium in the blood

Uncommon side effects—these may affect up to 1 in 100 people:

  • stroke
  • severe bleeding in digestive tract (stomach and intestine) and brain
  • a dangerous rapid fluttering of the heart (Torsades de Pointes)
  • hole (perforation) in digestive tract
  • abnormal connection between parts of the digestive tract (fistula)
  • a sudden and severe rise in blood pressure which may be life-threatening
  • liver failure

Other side effects that have occurred at an uncommon rate:

  • infections, with or without changes in white blood cells (cells that fight infection)
  • inflammation of the pancreas
  • separation or tear of the lining of the back part of the eye (retinal detachment or tear). This can result in trouble seeing (blurry or impaired vision).

Other side effects that have occurred rarely—these may affect up to 1 in 1000 people:

  • blood clots accompanied by a decrease in red blood cells and cells involved in clotting. These clots may harm organs such as the brain and kidneys.

Side Effects with Unknown Frequency:

  • Interstitial lung disease, a form of lung scarring or inflammation, can have a fatal outcome in some cases. If you develop symptoms such as sudden difficulty of breathing associated with cough or fever contact your doctor immediately.
  • reversible swelling in the rear part of the brain that can be associated with high blood pressure and can lead to headache, loss of speech or vision, abnormal drowsiness, confusion and/or seizure (Posterior Reversible Encephalopathy Syndrome or Reversible Posterior Leukoencephalopathy Syndrome)

Interactions with this medication

Tell your doctor or pharmacist if you are taking, or have recently taken any other medicines including any medicines you bought without a prescription. This includes herbal medicines.

Some medicines may affect the way VOTRIENT works or VOTRIENT may affect how other medicines work. These include:

  • clarithromycin, ketoconazole, itraconazole, telithromycin, voriconazole (used to treat infections)
  • atazanavir, indinavir, nelfinavir, ritonavir, saquinavir (used to treat HIV)
  • dextromethorphan (used in cough medicines)
  • simvastatin and possibly other statins (used to treat high cholesterol levels)
  • medicines that reduce stomach acid (e.g. esomeprazole, ranitidine, magnesium hydroxide)

Also, the following list includes some, but not all, of the drugs that may interact with VOTRIENT to affect the electrical activity of your heart:

  • Antiarrhythmics (drugs that stabilize the heart rhythm function, such as quinidine, procainamide, amiodarone, sotalol, etc.)
  • Antidepressants (mood disorder drugs)
  • Antipsychotics (drugs used to stabilize thinking and behaviour)
  • Opioids (e.g. methadone)
  • Macrolide antibiotics (such as erythromycin, clarithromycin)
  • Fluoroquinolone antibiotics (such as moxifloxacin, levofloxacin, ciprofloxacin)
  • Antifungals (such as fluconazole, voriconazole)
  • Antimalarials (e.g. quinine)
  • Antinauseants (e.g. granisetron, ondansetron, dolasetron)
  • Anti-asthmatics (e.g. salmeterol, formoterol)
  • Tacrolimus (used after organ transplant to prevent rejection)
  • Certain anticancer treatments (e.g. sunitinib, nilotinib, lapatinib, sorafenib, vorinostat)

VOTRIENT is affected by food intake. You should not drink grapefruit juice or eat grapefruit while you are being treated with VOTRIENT as this may increase the chance of side effects.

Proper Use of this medication

Always take VOTRIENT exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Usual dose:

The usual dose is 800 mg VOTRIENT, taken once a day.

Do not take more than 800 mg VOTRIENT a day.

Swallow the tablets whole with water, one after the other, at about the same time each day. Do not break or crush the tablets as it affects the way the medicine is absorbed and may increase the chance of side effects.

It is important that you take VOTRIENT either at least one hour before or at least two hours after food.

Depending on your response to treatment, your doctor may recommend adjusting your dose or temporarily stopping your treatment.

Overdose:

If you have accidentally taken more VOTRIENT tablets than you should, contact your doctor, or poison control centre, or go to the emergency room of the nearest hospital even if there are no symptoms.

Missed dose:

If you forget to take VOTRIENT, do not take a double dose to make up for a missed dose. Take the next dose at the scheduled time.

Other related products

Xeloda (Capecitabine)

Author , posted on June 15, 2017

Category:


Xeloda

Capecitabine

Select Quantity:

Xeloda

Capecitabine

Select Quantity:

Capecitabine (Generic)

Capecitabine

Select Quantity:

Capecitabine (Generic)

Capecitabine

Select Quantity:
Select Quantity:

Capecitabine (Generic)

Capecitabine

Select Quantity:

Xeloda (Capecitabine) Medication Information

Uses

Xeloda is a nucleoside metabolic inhibitor that is used to treat colon cancer and breast cancer. 

Dosage

The tablets are available in several different strengths:

  • 150 mg
  • 500 mg

Side Effects

The most common side effects of Xeloda include:

  • Abdominal pain
  • Vomiting
  • Nausea
  • Diarrhea 
  • Hand-and-foot syndrome
  • Fatigue
  • Increase in bilirubin 

Speak with your doctor for a full list of side effects that apply to you if you are taking Capecitabine.

Precautions

In patients with low or absent dihydropyrimidine dehydrogenase (DPD) there is a risk of developing serious side effects when taking Capecitabine. 

In patients who are dehydrated there is a risk of kidney injury and Xeloda treatment should be held until dehydration is corrected. 

There is a risk of coagulopathy, and patients who take Xeloda will need to have their blood monitored. 

Interactions

A common drug interaction with Xeloda includes:

  • Anticoagulants
  • Phenytoin
  • Leucovorin
  • Food 

Speak with your doctor for more information and before starting a new medication with Capecitabine. 

Storage

Store at room temperature (77 ºF). Keep Xeloda in a tightly closed container.

Pharmacist Tips

  • If you experience a side effect with Xeloda it is important to report it to your doctor. 
  • Xeloda tablets need to be swallowed whole.
  • Capecitabine dose is calculated based on your body surface area, so if there is significant weight changes your dose may need to be changed. .

Capecitabine FAQs

How long before Xeloda side effects start?

You can see side effects with Xeloda a few days after starting therapy.

 

What happens when you stop Xeloda?

You should not stop taking Capecitabine unless instructed by your doctor. 

 

How long can you stay on Xeloda?

Xeloda is typically given as a 14 day treatment in a 21 day cycle. The number of cycles that are recommended is based on your cancer type. 

 

Can Xeloda cure cancer?

Capecitabine is approved to treat colon and breast cancer. 

 

What are Xeloda side effects?

Capecitabine can cause abdominal discomfort, nausea, vomiting, diarrhea, hand-and-foot syndrome, and mouth sores. 

 

Related Drugs

Reference:

Xeloda {package insert}. South San Francisco: Genetech USA, Inc.; 2015.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020896s037lbl.pdf

PharmD Medical Writer

Author: Dr. Larisa Roybal, PharmD

Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.

Xerese Cream (Acyclovir/Hydrocortisone)

Author , posted on June 15, 2017

Category:


Xerese

Acyclovir, Hydrocortisone

Select Quantity:

Xerese Cream (Acyclovir/Hydrocortisone) Usage and Side Effects

XERESE (acyclovir and hydrocortisone) is a prescription medicine used in people ages 12 and older to lessen the chance of a cold sore becoming worse (ulcerating).

Warnings and Precautions

XERESE is for cold sores on lips and around the mouth only. XERESE should not be used in eyes, mouth, nose, genitals, AROUND THE ANUS OR ON ANY MUCOUS MEMBRANE.

This product should not be used if you are severely immunocompromised (e.g. have HIV, cancer or are a transplant patient).

BEFORE you use XERESE talk to your doctor or pharmacist if you:

  • Have a weak immune system (become sick very easily). It is not known if XERESE will harm you.
  • Have any other medical conditions.
  • Are pregnant or plan to become pregnant. It is not known if XERESE will harm your unborn baby.
  • Are breast-feeding or plan to breast-feed. It is not known if XERESE is passed in your milk to your baby.

Side Effects

Like all medicines, XERESE can cause side effects, although not everybody gets them.

The most common side effects of XERESE are: drying or flaking of the skin, tingling or burning, redness of the skin, changes in your skin color where the cream is applied (pigmentation changes), swelling, bitter taste after you apply XERESE. If these effects become bothersome, contact your doctor.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of XERESE. For more information, ask your doctor or pharmacist.

Interactions with this medication

 Inform your doctor or pharmacist about all of your medicines, including over-the-counter drugs that may interact with XERESE.

No drug interaction studies were done for XERESE.

Proper Use of this medication

Use XERESE exactly as directed by your doctor.

Use XERESE early, at the first sign of a cold sore (e.g. itching, burning, tingling or redness).

In case of accidental contact with the eyes or the inside of the nose or mouth, rinse thoroughly with water.

To avoid spreading the infection, do not share this medicine.

Wash your hands before and after using XERESE.

Clean and dry the skin before applying XERESE. Spread a thin layer of XERESE on the affected area.

Do not rub the cold sore because it may spread to other areas around your mouth, or make your cold sore worse.

Do not cover the cold sore or area around the cold sore with a bandage.

Do not use other skin products (such as make-up, sun screen or lip balm) or other skin medicine on the cold sore or area around the cold sore.

Do not bathe, shower or swim until 30 minutes after applying XERESE.

Talk to your doctor if your cold sore is not better in 2 weeks.

Usual adult dose:

Apply XERESE topically 5 times per day for 5 days. You should topically apply a quantity of XERESE sufficient to cover the affected area, including the outer margin. Avoid unnecessary rubbing of the affected area to avoid aggravating or transferring the infection. Wash your hands before and after the use of the cream to avoid spreading the infection.

For adolescents 12 years of age and older, the dosage is the same as in adults.

Overdose:

In case of drug overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.

Missed dose:

If you miss a dose of XERESE, apply it as soon as possible. However, if it is almost time for your next dose, go back to your regular dosing schedule. Do not use extra medicine to make up the missed dose.

Other related products

Zortress (Everolimus)

Author , posted on June 15, 2017

Category:


Certican

Everolimus

Select Quantity:
Select Quantity:
Select Quantity:

Zortress

Everolimus

Select Quantity:
Select Quantity:

Zortress (Everolimus) Dosage and Side Effects

ZORTRESS is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body.

Warnings and Precautions

ZORTRESS can cause serious and sometimes fatal side effects. Call your doctor right away if you have symptoms such as: fever, chills, joint pain, cough, chest pain, wheezing, trouble breathing, swelling, little or no urinating, loss of appetite, dark urine, yellowing of your skin or eyes, or upper stomach pain.

ZORTRESS may increase your risk of infection or certain cancer by changing the way your immune system works.

Serious and sometimes fatal infections may occur during treatment with ZORTRESS . Stop using this medicine and call your doctor right away if you have signs of infection such as: fever, chills, body aches, or flu symptoms.

ZORTRESS can cause a blood clot in the blood vessels of your transplanted organ, especially within 30 days after transplant. Tell your doctor right away if you have: shortness of breath, fever with nausea or vomiting, blood in your urine, dark colored urine, little or no urinating, jaundice (yellowing of your skin or eyes), or pain in your stomach, groin, lower back, or side.

You should not use this medicine if you are allergic to ZORTRESS, sirolimus (Rapamune), tacrolimus (Prograf), or temsirolimus (Torisel).

To make sure ZORTRESS is safe for you, tell your doctor if you have:

  • an active infection, or history of chronic infections;
  • liver disease, or a history of hepatitis B;
  • kidney disease;
  • diabetes or high blood sugar;
  • high cholesterol;
  • if you are scheduled to receive any vaccine; or
  • if you also take an "ACE inhibitor" heart or blood pressure medication, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril.

Do not take ZORTRESS if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 8 weeks after your treatment ends.

ZORTRESS can affect fertility (your ability to have children), whether you are a man or a woman.

It is not known whether ZORTRESS passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking ZORTRESS.

You should not use this medication if you are allergic to ZORTRESS or sirolimus (Rapamune), or if you have problems digesting lactose or galactose (sugar).

ZORTRESS can lower blood cells that help fight infection, and may cause you to produce too much of a certain type of white blood cell. This can lead to serious conditions including cancer, severe brain infection causing disability or death, or a viral infection causing kidney transplant failure. Ask your doctor about your specific risk.

To make sure you can safely take ZORTRESS, tell your doctor if you have any of these other conditions:

  • high cholesterol or triglycerides;
  • diabetes or high blood sugar;
  • a breathing disorder, such as asthma or COPD (chronic obstructive pulmonary disease);
  • a personal or family history of skin cancer (melanoma); or
  • if you have ever had a heart transplant.

It is not known whether ZORTRESS will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Use effective birth control while you are using this medication and for at least 8 weeks after your treatment ends.

ZORTRESS can lower sperm count in men, which may affect fertility (your ability to have children).

It is not known whether ZORTRESS passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking ZORTRESS.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have some of these symptoms if you also take an "ACE inhibitor" heart or blood pressure medication.

Stop using ZORTRESS and call your doctor at once if you have:

  • new or worsening cough, chest pain, wheezing, feeling short of breath;
  • signs of infection--fever, chills, joint pain, red or swollen gums, painful mouth sores, skin sores, rapid heart rate, pale skin, easy bruising, unusual bleeding, feeling light-headed;
  • kidney problems--little or no urination; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath;
  • liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • any wound that will not heal; or
  • a surgical incision that is red, warm, swollen, painful, bleeding, or oozing pus.

Common side effects may include:

  • infections, cough, nosebleeds;
  • mouth sores, taste problems, dry mouth;
  • nausea, vomiting, diarrhea, constipation;
  • weight loss, feeling weak or tired;
  • pain or swelling anywhere in your body;
  • dry skin, rash, acne;
  • missed menstrual periods;
  • unusual changes in mood or behavior;
  • sleep problems (insomnia);
  • dizziness, headache; or
  • high blood sugar--increased thirst or urination, hunger, fruity breath odor, blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Get emergency medical help if you have signs of an allergic reaction: hives; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat.

Serious and sometimes fatal infections may occur during treatment with ZORTRESS. Stop using this medicine and call your doctor right away if you have signs of infection such as: fever, chills, body aches, or flu symptoms.

ZORTRESS can cause a blood clot in the blood vessels of your transplanted organ, especially within 30 days after transplant. Tell your doctor right away if you have: shortness of breath, fever with nausea or vomiting, blood in your urine, dark colored urine, little or no urinating, jaundice (yellowing of your skin or eyes), or pain in your stomach, groin, lower back, or side.

Call your doctor at once if you have:

  • pain or burning when you urinate;
  • redness, warmth, swelling, oozing, or slow healing of a wound or surgical incision;
  • new or worsening cough, wheezing, breathing problems;
  • stabbing chest pain, cough with yellow or green mucus;
  • pale skin, feeling light-headed, rapid heart rate, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum);
  • white patches or sores inside your mouth or on your lips;
  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);
  • high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss); or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, uneven heartbeats, seizure).

Common side effects may include:

  • swelling in your legs, ankles, or feet;
  • diarrhea, constipation; or
  • mild stomach discomfort.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Interactions with this medication

If you develop mouth sores or ulcers, avoid using mouthwashes or applying medicines that contain alcohol, peroxide, iodine, or thyme.

Do not receive a "live" vaccine while using ZORTRESS, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

This medicine can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Grapefruit and grapefruit juice may interact with ZORTRESS and lead to unwanted side effects. Avoid the use of grapefruit products while taking ZORTRESS.

This medicine can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Do not receive a "live" vaccine while using ZORTRESS, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

ZORTRESS may increase your risk of developing skin cancer. Avoid exposure to sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Grapefruit and grapefruit juice may interact with ZORTRESS and lead to unwanted side effects. Avoid the use of grapefruit products while taking ZORTRESS.

Many drugs can interact with ZORTRESS. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

  • an antibiotic;
  • antifungal medicine;
  • heart or blood pressure medication;
  • medicine to treat hepatitis C, or HIV/AIDS;
  • seizure medicine;
  • St. John's wort;
  • tuberculosis medication; or
  • drugs that weaken the immune system, such as cancer medicine, steroids, and medicines to prevent organ transplant rejection.

This list is not complete and many other drugs can interact with ZORTRESS. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Many drugs can interact with ZORTRESS. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with ZORTRESS, especially:

  • aprepitant, conivaptan, cyclosporine, deferiprone, imatinib, natalizumab; or
  • an antibiotic--clarithromycin, dalfopristin, erythromycin, telithromycin; an antidepressant--fluvoxamine, nefazodone; antifungal medication--fluconazole, itraconazole, ketoconazole; heart or blood pressure medication--diltiazem, verapamil; HIV/AIDS medication--atazanavir, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir.

This list is not complete and many other drugs can interact with ZORTRESS. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Proper Use of this medication

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

ZORTRESS should be taken at the same time each day. You may take ZORTRESS with or without food, but take it the same way each time.

Do not take a ZORTRESS regular tablet together with an ZORTRESS dispersible tablet. Use only one form of this medicine.

Take the ZORTRESS regular tablet with a full glass of water. Do not crush, chew, or break the tablet. Swallow the pill whole.

Do not swallow the dispersible tablet (Afinitor Disperz) whole. Place it into about 2 tablespoons of water and allow the tablet to disperse in the liquid for at least 3 minutes. Stir gently and drink this mixture right away. The dispersed tablet may also be taken with an oral syringe. Wear latex gloves while handling the ZORTRESS Disperz tablet.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

ZORTRESS can lower blood cells that help your body fight infections and help your blood to clot. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often.

If you have ever had hepatitis B, ZORTRESS can cause this condition to come back or get worse. You will need frequent blood tests to check your liver function during treatment and for several months after you stop using this medicine.

If you need surgery, tell the surgeon ahead of time that you are using ZORTRESS. Your surgical incisions or other wounds may take longer to heal while you are taking this medicine.

Store at room temperature in the original container, away from moisture, heat, and light. Keep each tablet in its blister pack until you are ready to take it.

ZORTRESS is usually taken twice daily (every 12 hours). Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take the medicine with or without food, but take it the same way each time. If you also take cyclosporine or tacrolimus, take both medications at the same time.

Do not stop taking ZORTRESS or change your dose without first talking to your doctor.

Take this medication with a full glass (8 ounces) of water.

Do not crush or chew a ZORTRESS tablet. Swallow the pill whole.

While using ZORTRESS, you will need frequent blood and urine tests at your doctor's office.

Store at room temperature in the original container, away from moisture, heat, and light. Keep each tablet in its blister pack until you are ready to take it.

Take the missed dose as soon as you remember. If you are more than 6 hours late, skip the missed dose. Do not take extra medicine to make up the missed dose.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Other related products

Zebeta (Bisoprolol)

Author , posted on June 15, 2017

Category:


Zebeta

Bisoprolol Fumarate

Select Quantity:
Select Quantity:
Select Quantity:

Zebeta

Bisoprolol Fumarate

Select Quantity:

Bisoprolol (Generic)

Bisoprolol Fumarate

Select Quantity:
Select Quantity:
Select Quantity:
Select Quantity:
Select Quantity:
Select Quantity:

Bisoprolol (Generic)

Bisoprolol Fumarate

Select Quantity:
Select Quantity:

Zebeta (Bisoprolol) Dosage and Side Effects

ZEBETA is used to treat high blood pressure and is also sometimes used to treat heart failure. ZEBETA belongs to a class of drugs called beta-blockers. It works by relaxing blood vessels, slowing the heart rate, and decreasing the heart's contractility.

Warnings and Precautions

Before taking ZEBETA, tell your doctor if you have, or have ever had:

  • A lung disease, such as asthma, chronic bronchitis, or emphysema
  • Heart failure, heart disease, a slow heart rate, or any other heart condition
  • Circulation problems
  • An overactive thyroid
  • Liver disease
  • Kidney disease
  • Diabetes
  • A mental illness, such as depression
  • Allergies

If you suffer from allergies, you should know that ZEBETA may worsen your allergic reactions. Talk to your doctor if this is a concern for you.

If you have diabetes, ZEBETA may make it more difficult to recognize symptoms of hypoglycemia (low blood glucose). Discuss this potential effect with your doctor.

Let your healthcare provider know you're taking ZEBETA before having any type of surgery, including a dental procedure.

Your doctor will want to monitor your condition closely while you take ZEBETA. Keep all appointments with your doctor's office and laboratory.

Your doctor may tell you to adopt certain diet and lifestyle changes while taking ZEBETA. Follow these instructions carefully.

ZEBETA helps control high blood pressure, but it won't cure the condition. Continue to take the medicine even if you feel well.

Don't stop taking ZEBETA without first talking to your doctor. Your doctor might want to take you off the drug gradually, by reducing your dose a little bit at a time.

Pregnancy and ZEBETA

It's not known whether ZEBETA can harm an unborn baby.

Tell your doctor if you're pregnant, or might become pregnant while taking the medicine.

It's also not known whether ZEBETA passes into breast milk or could hurt a breastfeeding baby. Talk to your doctor before breastfeeding.

Side Effects

Tell your doctor if any of the following side effects become severe or don't go away:

  • Diarrhea
  • Vomiting
  • Constipation
  • Increased urination
  • Dry mouth
  • Tiredness
  • Dizziness
  • Mild itching
  • Mild joint or muscle aches
  • Insomnia
  • Depression or anxiety
  • Restlessness
  • Loss of interest in sex
  • Runny or stuffy nose

Serious Side Effects:

Tell your doctor right away if you experience any of the following serious side effects:

  • Swelling of the hands, feet, ankles, or lower legs
  • Unusual weight gain
  • Shortness of breath
  • Fast, slow, or pounding heartbeat
  • Chest pain
  • Fainting
  • Painful urination
  • Numbness, tingling, or cold feeling in your hands and feet
  • Confusion
  • Hallucinations
  • Signs of an allergic reaction (may include hives, rash, itching, chest tightness, or swelling of the face, lips, tongue, or throat)

Interactions with this medication

Tell your doctor about all prescription, nonprescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking, especially:

  • Calcium channel blockers, such as diltiazem (Cardizem, Cartia XT, Dilacor XR, or Tiazac), verapamil (Calan, Covera-HS, or Verelan), or Tarka (trandolapril and verapamil)
  • Catapres or Kapvay (clonidine) or Clorpres (clonidine and chlorthalidone)
  • Gilenya (fingolimod)
  • Medications for breathing disorders, such as albuterol (Ventolin or Proventil), Tornalate (bitolterol), Alupent (metaproterenol), Maxair (pirbuterol), or terbutaline (Brethaire, Brethine, or Bricanyl)
  • Medications for diabetes (including insulin)
  • Medications for irregular heartbeat, such as Norpace (disopyramide)
  • Other beta-blockers, such as Tenormin (atenolol), Coreg (carvedilol), Normodyne or Trandate (labetalol), Lopressor or Toprol (metoprolol), Corgard (nadolol), Inderal or InnoPran (propranolol), or Betapace (sotalol)
  • Reserpine
  • Rifadin or Rimactane (rifampin), Rifater (rifampin, isoniazid, and pyrazinamide), or Rifamate (rifampin and isoniazid)

ZEBETA and Other Interactions

ZEBETA may make you drowsy.

Don't drive a car or perform any activity that requires alertness until you know how this medicine affects you.

ZEBETA and Alcohol

Alcohol may worsen certain side effects of ZEBETA .

Talk to your doctor before drinking alcohol while taking this medicine.

Proper Use of this medication

ZEBETA comes as a tablet to take by mouth. It's usually taken once a day.

Take ZEBETA with a full glass of water, and try to use the medicine around the same time each day.

Your dose will be based on your medical condition and response to treatment.

Follow the instructions on your prescription label carefully. Don't take more or less ZEBETA than is recommended.

Your doctor will probably start you on a low dose of ZEBETA and gradually increase it.

Overdose:

Symptoms of a ZEBETA overdose may include:

  • Wheezing or shortness of breath
  • Dizziness
  • Slow heart rate
  • Anxiety
  • Confusion
  • Nausea
  • Sweating
  • Pale skin
  • Fainting
  • Seizure

If you suspect an overdose, contact a poison control center or emergency room immediately.

Missed Dose:

If you miss a dose of ZEBETA , take it as soon as you remember.

But if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular medication schedule.

Don't take extra medicine to make up for a missed dose.

Other related products

Zaditor Eye Drops (Ketotifen)

Author , posted on June 15, 2017

Category:


Zaditor Eye Drops

Ketotifen Fumarate

Select Quantity:

Zaditor Eye Drops

Ketotifen Fumarate

Select Quantity:

Zaditor Eye Drops (Ketotifen) Dosage and Side Effects

ZADITOR is an antihistamine that inhibits the body's release of a chemical called histamine. Histamine can produce allergy symptoms such as sneezing, runny nose, and watery eyes.  ZADITOR ophthalmic is used to treat itching of the eyes caused by allergy to dust, pollen, animals, or other allergens.

Warnings and Precautions

Do not use this medication if you are allergic to ZADITOR, or if you have an untreated eye infection. ZADITOR ophthalmic should not be used to treat eye irritation caused by wearing contact lenses.

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended.

If you wear contact lenses, remove them before applying ZADITOR ophthalmic. This medication may contain a preservative (benzalkonium chloride) that may cause discoloration of contact lenses. Wait at least 10 minutes after using in the eye drops before putting contact lenses into your eyes.

Do not allow the medicine dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use this medication if you are allergic to ZADITOR, or if you have an untreated eye infection. ZADITOR ophthalmic should not be used to treat eye irritation caused by wearing contact lenses.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether ZADITOR passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not use this medication in a child younger than 3 years old without the advice of a doctor.

Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using ZADITOR ophthalmic and call your doctor at once if you have any of these serious side effects:

  • redness, drainage, eyelid swelling, or other signs of infection;
  • eye pain;
  • vision changes; or
  • severe itching of the eyes worse than before using the medication.

Less serious side effects may include:

  • mild burning, stinging, or eye irritation;
  • dryness of the eyes; or
  • increased sensitivity to light.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

Interactions with this medication

Avoid using other medications in your eyes during treatment with ZADITOR ophthalmic unless your doctor has told you to.

There may be other drugs that can interact with ZADITOR ophthalmic. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Proper Use of this medication

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended.

Wash your hands before using the eye drops.

If you wear contact lenses, remove them before applying ZADITOR ophthalmic. This medication may contain a preservative (benzalkonium chloride) that may cause discoloration of contact lenses.

To apply the eye drops:

  • Tilt your head back slightly and pull down your lower eyelid. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye. Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct. If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.

Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

After using the eyedrops, wait at least 10 minutes before putting contact lenses into your eyes.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your doctor for a new prescription.

Store the drops at room temperature away from heat and moisture. Keep the bottle tightly closed when not in use.

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of ZADITOR ophthalmic is not expected to produce life-threatening symptoms.

Use the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

Other related products

Protonix (Pantoprazole)

Author , posted on June 15, 2017

Category:


Protonix

Pantoprazole Sodium

Select Quantity:

Protonix

Pantoprazole Sodium

Select Quantity:
Select Quantity:

Protonix

Pantoprazole Sodium

Select Quantity:
Select Quantity:

Pantoprazole (Generic)

Pantoprazole Sodium

Select Quantity:
Select Quantity:

Protonix (Pantoprazole) Dosage and Side Effects

PROTONIX is a prescription drug used as a short-term treatment for gastroesophageal reflux disease (GERD). PROTONIX may also be used for a longer period of time for maintenance or healing of erosive esophagitis, and to treat conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome.

Warnings and Precautions

PROTONIX shouldn't be used for the immediate relief of heartburn symptoms.

Don't take PROTONIX if you're allergic to any other benzimidazole medications such as albendazole (Albenza) or mebendazole (Vermox).

Long-term use of PROTONIX may make it harder for your body to absorb vitamin B-12, which could result in a B-12 deficiency.

PPI use may also increase your risk for fractures in your wrists, hips, or spine. In 2010, however, the FDA decided that there was not enough evidence of fracture risk to merit a warning.

Extended use of PROTONIX has been shown to cause stomach cancer in animal studies, but researchers are unsure if the medication has the same effects in humans.

PROTONIX may be used in children five years of age and older for up to eight weeks to heal acid-related damage to the esophagus. It's not known if the drug is safe for longer than eight weeks of use in children.

Tell your doctor if you are allergic to any of the ingredients in PROTONIX. You can ask your pharmacist for a list of the ingredients.

PROTONIX and Magnesium

Low magnesium levels can also occur in people on PROTONIX for at least three months.

Tell your doctor if you have ever had low magnesium in your blood or if you have ever tested positive for the bacteria H. pylori.

Low magnesium levels can result in serious adverse events such as:

  • Muscle spasms
  • Irregular heartbeat
  • Seizures

If you have low magnesium levels while using PROTONIX, your doctor may advise you to take a magnesium supplement or discontinue treatment.

PROTONIX and Pregnancy

Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding before taking PROTONIX.

Although there is no evidence suggesting that PROTONIX use is harmful during pregnancy, it's recommended that the drug only be used during pregnancy as needed, when no other options are available.

Research indicates that PROTONIX and its metabolites are excreted in the milk of rats, and that they may be excreted in human breast milk as well.

The manufacturer recommends that due to the potential for serious adverse reactions in breastfeeding infants, mothers using PROTONIX may want to discontinue breastfeeding or discontinue use of the drug.

Side Effects

The most common side effects of PROTONIX include:

  • Headache
  • Diarrhea
  • Nausea
  • Vomiting
  • Gas
  • Joint pain
  • Constipation

You should call your doctor immediately or get emergency medical help if you experience any of the following side effects:

  • Blistering or peeling skin
  • Rash
  • Hives
  • Itching
  • Swelling of the eyes, face, lips, mouth, throat or tongue
  • Muscle spasms
  • Uncontrollable shaking of a body part
  • Seizures
  • Difficulty breathing or swallowing
  • Hoarseness
  • Irregular, fast, or pounding heartbeat
  • Excessive tiredness
  • Dizziness
  • Lightheadedness
  • Severe diarrhea
  • Stomach pain
  • Fever

Interactions with this medication

Before taking PROTONIX, tell your doctor and pharmacist about all medications you are taking (including vitamins and herbal supplements).

PROTONIX shouldn't be taken with atazanavir (Reyataz) or nelfinavir (Viracept), which are medications used to treat HIV and AIDS.

Other drugs that may interact with PROTONIX include:

  • Ampicillin (Omnipen, Principen, Amcill)
  • Warfarin (Coumadin, Jantoven)
  • Digoxin (Lanoxin, Lanoxicaps)
  • Diuretics (water pills)
  • Antifungals such as ketoconazole (Nizoral), itraconazole (Sporanox), and voriconazole (Vfend)
  • Iron supplements/ferrous sulfate (Feosol, Mol-Iron, Fergon, Femiron)
  • Methotrexate (Trexall)
  • Delavirdine (Rescriptor)

Unless otherwise instructed, you can continue a normal diet and normal activities while taking PROTONIX.

Proper Use of this medication

PROTONIX is supplied as a granule for delayed-release oral suspension, available in one strength (40 mg), and as a delayed-release tablet, available in two strengths (20 mg and 40 mg).

It's also available in an intravenous (IV) solution for hospital use.

Typically, your doctor will prescribe 40 mg daily for four to eight weeks of treatment. The medication should be taken around the same time each day.

Take PROTONIX for the full prescribed length of time as your symptoms may improve before your condition is completely treated.

Delayed-Release PROTONIX

The tablet form of PROTONIX is released in the intestine to prevent breakdown of the medication by stomach acids.

The tablets are usually taken with or without food one or two times daily.

Swallow the tablets whole. Do not split, chew, or crush them.

Delayed Release Granules for Suspension

The packets of delayed-release granules for oral suspension must be mixed with applesauce or apple juice and taken by mouth or given through a feeding tube.

The oral suspension is usually taken 30 minutes before a meal, once or twice daily.

PROTONIX Overdose

Evidence on the effects of PROTONIX overdose in humans is limited.

Symptoms of overdose in studies of PROTONIX in rats, mice, and dogs included:

  • Hypoactivity
  • Ataxia
  • Tremor

If you suspect an overdose, you should seek emergency medical attention or call the Poison Help Line.

PROTONIX Missed Dose

If you miss a dose of PROTONIX, take it as soon as you remember.

You should skip the missed dose if it is almost time for your next scheduled dose.

Don't take extra doses of this drug.

Other related products

Zanaflex (Tizanidine Hydrochloride)

Author , posted on June 15, 2017

Category:


Zanaflex

Tizanidine Hydrochloride

Select Quantity:

Zanaflex

Tizanidine Hydrochloride

Select Quantity:

Tizanidine (Generic)

Tizanidine

Select Quantity:
Select Quantity:

Tizanidine (Generic)

Tizanidine Hydrochloride

Select Quantity:

Zanaflex (Tizanidine Hydrochloride) Dosage and Side Effects

ZANAFLEX is used to treat muscle spasms caused by certain conditions such as multiple sclerosis, ALS, or spinal cord injury.

Warnings and Precautions

ZANAFLEX is a short-acting medication that you should only take for daily activities that require relief from muscle spasms.

Using too much ZANAFLEX can severely damage your liver, causing liver failure.

Tell your doctor if you have any type of previous injury to your liver. Your doctor will likely check blood levels after a month of use if you fall into this category.

It's also important to inform your doctor if you have experienced kidney failure.

Call your doctor immediately if you develop dry mouth, dizziness, a strong desire for sleep, or any sign of weakness while taking ZANAFLEX. Your dosage may have to be reduced or discontinued.

You should not drive, use heavy machinery, or do any activity that requires you to be alert while using ZANAFLEX.

If you are scheduled for surgery, let your doctor know you are taking ZANAFLEX.

Before having surgery, tell your doctor or dentist about all the products you use, including over-the-counter (OTC) drugs.

In older adults, the effects of ZANAFLEX may also last much longer.

Pregnancy and ZANAFLEX

ZANAFLEX may be harmful to an unborn baby.

Animal studies have shown an adverse effect, but there are no adequate studies in pregnant women. Tell your doctor if you are pregnant or might become pregnant during treatment.

Do not use this medication without telling your doctor if you are breastfeeding.

ZANAFLEX 'High' and Recreational Use

Because of ZANAFLEX's sedative effects, numerous online and anecdotal reports have suggested that some people abuse the drug for a narcotic-like "high."

However, ZANAFLEX is not a narcotic.

Side Effects

ZANAFLEX has some common side effects that should go away with continued use, including:

  • Dry mouth
  • Weakness
  • Fatigue
  • Dizziness
  • Nervousness
  • Depression
  • Vomiting
  • Tingling sensation in the arms, legs, hands, and feet
  • Constipation
  • Diarrhea
  • Stomach pain
  • Heartburn
  • Increased muscle spasms
  • Back pain
  • Rash
  • Sweating
  • Light-colored stools

Tell your doctor if any of these symptoms are severe or do not go away.

Serious Side Effects of ZANAFLEX

Some side effects of ZANAFLEX can be serious.

If you experience any of these symptoms, call your doctor immediately:

  • Nausea
  • Extreme tiredness
  • Unusual bleeding or bruising
  • Lack of energy
  • Loss of appetite
  • Pain in the upper right part of the stomach
  • Yellowing of the skin or eyes (jaundice)
  • Unexplained flu-like symptoms
  • Seeing things or hearing voices that do not exist
  • Slow heartbeat
  • Changes in vision

Let your doctor know if you have any other unusual problems while taking ZANAFLEX.

Interactions with this medication

Do not take ZANAFLEX if you are also taking the antidepressant fluvoxamine (Luvox) or the antibiotic ciprofloxacin (Cipro).

Let your doctor know about all other medicines and supplements you're taking before taking ZANAFLEX.

Using ZANAFLEX along with the following medicines is not recommended:

  • Acyclovir (Zovirax)
  • Ciprofloxacin (Cipro)
  • Dronedarone (Multaq)
  • Fluvoxamine (Luvox)
  • Pimozide (Orap)
  • Saquinavir (Invirase)
  • Thioridazine (Mellaril)

Food has a complex effect on how ZANAFLEX is absorbed and processed in the body.

Starting at a lower dose and gradually increasing the dose minimizes the risk for adverse effects.

Unless your doctor tells you otherwise, continue your normal diet and take your medicine when you eat.

Alcohol and ZANAFLEX

Alcohol increases the overall amount of drug in the bloodstream.

You should not drink alcohol while taking ZANAFLEX.

Proper Use of this medication

ZANAFLEX also reacts differently depending on whether you take it with food or on an empty stomach, or if you sprinkle the contents of the capsule on food.

The usual starting dose is 2 mg taken by mouth every six to eight hours. A maximum of three doses can be taken in a 24-hour period. Your doctor could increase the strength in 2- to 4-mg steps to help reach the optimum effect and tolerance for your condition.

In order to reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose.

Follow your doctor's instructions carefully.

ZANAFLEX Withdrawal

ZANAFLEX may cause you to have withdrawal reactions, especially if it has been used regularly for a long time or in high doses.

Withdrawal symptoms, such as anxiety, tremor, increased blood pressure, heart rate, and muscle tenseness, may occur if you suddenly stop using this medication.

To prevent this from happening, your doctor may reduce your dose gradually to discontinue your use of ZANAFLEX.

ZANAFLEX Overdose

Get immediate help or go to an emergency room if you suspect you have taken too much ZANAFLEX.

Symptoms of an overdose include:

  • Blurred vision
  • Chest pain
  • Confusion
  • Difficult or troubled breathing
  • Dizziness, faintness, or lightheadedness when getting up from a lying position
  • Irregular, fast or slow, or shallow breathing
  • Loss of consciousness
  • Pale or blue lips, fingernails, or skin
  • Severe sleepiness
  • Sweating

Missed Dose of ZANAFLEX

If your doctor has told you to take ZANAFLEX regularly, take the missed dose as soon as you remember it.

If it's almost time for your next dose, however, skip the missed dose and continue your regular schedule.

Don't "double up" to make up for a missed one.

Other related products

Other related products

Zarontin (Ethosuximide)

Author , posted on June 15, 2017

Category:


Zarontin

Ethosuximide

Select Quantity:

Zarontin (Ethosuximide) Dosage and Side Effects

ZARONTIN is an anti-epileptic medication, also called an anticonvulsant.  ZARONTIN is used alone or in combination with other medications to treat absence seizures (also called "petit mal" seizures) in adults and children.

Warnings and Precautions

ZARONTIN can cause a decrease in many types of blood cells (white cells, red cells, platelets). Call your doctor at once if you have any unusual bleeding, weakness, or any signs of infection, even if these symptoms first occur after you have been using the medication for several months.

ZARONTIN may also cause liver damage. Call your doctor if you have symptoms such as loss of appetite, stomach pain, or jaundice (yellowing of the skin or eyes).

You may have thoughts about suicide while taking this medication. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, depression, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Do not stop using ZARONTIN without first talking to your doctor, even if you feel fine. You may have increased seizures if you stop using ZARONTIN suddenly. You will need to use less and less before you stop the medication completely.

Contact your doctor if your seizures get worse or you have them more often while taking ZARONTIN.

Wear a medical alert tag or carry an ID card stating that you take ZARONTIN. Any medical care provider who treats you should know that you take seizure medication.

You should not use this medication if you are allergic to ZARONTIN or to other seizure medications.

To make sure you can safely take ZARONTIN , tell your doctor if you have any of these other conditions:

  • lupus;
  • liver disease;
  • kidney disease; or
  • a history of depression, mood problems, or suicidal thoughts or actions.

You may have thoughts about suicide while taking this medication. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments.

It is not known whether ZARONTIN is harmful to an unborn baby, but having a seizure during pregnancy could harm both mother and baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Follow your doctor's instructions about taking ZARONTIN while you are pregnant.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of ZARONTIN on the baby.

ZARONTIN passes into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

ZARONTIN should not be given to a child younger than 3 years old.

Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, depression, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have a serious side effect such as:

  • fever, chills, swollen glands, flu symptoms, sore throat, swollen glands, feeling very weak;
  • new or worsening cough with fever, trouble breathing;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • joint pain or swelling with mild fever, muscle aches;
  • chest pain, irregular heart rhythm, feeling short of breath;
  • patchy skin color, red spots, or a butterfly shaped skin rash over your cheeks and nose (worsens in sunlight);
  • skin rash, severe tingling, numbness, pain, muscle weakness;
  • upper stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);
  • confusion, hallucinations, unusual thoughts or behavior, extreme fear;
  • swelling, rapid weight gain, urinating less than usual or not at all;
  • the first sign of any skin rash, no matter how mild;
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling; or
  • worsening of seizures.

Less serious side effects may include:

  • upset stomach, mild nausea, stomach cramps, diarrhea, weight loss;
  • swelling in your tongue or gums;
  • headache, dizziness, drowsiness, feeling tired;
  • lack of balance or coordination; or
  • unusual vaginal bleeding.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Interactions with this medication

Do not drink alcohol. It can increase certain side effects of ZARONTIN.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for depression or anxiety can add to sleepiness caused by ZARONTIN. Tell your doctor if you regularly use any of these medicines, or any other seizure medication.

Before taking ZARONTIN, tell your doctor about all other seizure medications you use, especially:

  • phenobarbital (Solfoton);
  • phenytoin (Dilantin); or
  • valproic acid (Depakene, Stavzor).

This list is not complete and other drugs may interact with ZARONTIN. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Proper Use of this medication

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

ZARONTIN can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Your kidney and liver function may also need to be tested. Visit your doctor regularly.

Call your doctor at once if you have any unusual bleeding, weakness, or any signs of infection, including flu-like symptoms. These symptoms may first develop even after you have been using the medication for several months.

Do not stop using ZARONTIN without first talking to your doctor, even if you feel fine. You may have increased seizures if you stop using ZARONTIN suddenly. You may need to use less and less before you stop the medication completely.

Contact your doctor if your seizures get worse or you have them more often while taking ZARONTIN.

Wear a medical alert tag or carry an ID card stating that you take ZARONTIN. Any medical care provider who treats you should know that you take seizure medication.

Use ZARONTIN regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store at room temperature away from moisture and heat.

Overdose symptoms may include nausea, vomiting, extreme drowsiness, and weak or shallow breathing.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Other related products