The most common short-term side effects are minor pain at the injection site and minor buildup of joint fluid. These get better within a few days. Infrequently theinjected joint may flare up with increased inflammation.

interactions info....

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. DURICEF will not treat a viral infection such as the common cold or flu.

DURICEF can be taken on an empty stomach or with food or milk if it causes stomach upset.

Shake the liquid form of DURICEF well before measuring a dose. To ensure that you get a correct dose, measure the suspension with a dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

This medication can cause you to have false results with certain medical tests, including urine glucose (sugar) tests. Tell any doctor who treats you that you are using DURICEF.

Store the tablets and capsules at room temperature away from moisture and heat.

Store DURICEF oral liquid in the refrigerator. Do not allow it to freeze. Throw away any unused medication that is older than 14 days.

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a DURICEF overdose are not known.

Take the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• diarrhea that is watery or bloody;
• fever, chills, body aches, flu symptoms;
• unusual bleeding or bruising;
• seizure (convulsions);
• pale or yellowed skin, dark colored urine, fever, confusion or weakness;
• jaundice (yellowing of the skin or eyes);
• fever, swollen glands, rash or itching, joint pain, or general ill feeling;
• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
• increased thirst, loss of appetite, swelling, weight gain, feeling short of breath, urinating less than usual or not at all.

Less serious side effects may include:

• nausea, vomiting, stomach pain, mild diarrhea;
• stiff or tight muscles;
• joint pain;
• feeling restless or hyperactive;
• unusual or unpleasant taste in your mouth;
• mild itching or skin rash; or
• vaginal itching or discharge.

Do not take this medication if you are allergic to DURICEF, or to similar antibiotics, such as Ceftin, Cefzil, Keflex, Omnicef, and others.

Before taking this medication, tell your doctor if you are allergic to any drugs (especially penicillin). Also tell your doctor if you have kidney disease or a history of intestinal problems.

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. DURICEF will not treat a viral infection such as the common cold or flu.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

Do not take this medication if you are allergic to DURICEF or to other cephalosporin antibiotics, such as:

• cefaclor (Raniclor);
• cefazolin (Ancef);
• cefdinir (Omnicef);
• cefditoren (Spectracef);
• cefpodoxime (Vantin);
• cefprozil (Cefzil);
• ceftibuten (Cedax);
• cefuroxime (Ceftin);
• cephalexin (Keflex); or
• cephradine (Velosef); and others.

Before taking DURICEF, tell your doctor if you are allergic to any drugs (especially penicillins), or if you have:

• kidney disease; or
• a history of intestinal problems, such as colitis.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take DURICEF.

The DURICEF suspension (liquid) contains sucrose. Talk to your doctor before using this form of DURICEF if you have diabetes.

This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

DURICEF may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

There may be other drugs that can interact with DURICEF. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start taking a new medication without telling your doctor.

There are different brands of this medication available. They may not have the same effects. Do not change brands without asking your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually 2-3 times daily. Take lithium with or immediately after meals to lessen stomach upset. Do not crush or chew this medication. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

Drink 8 to 12 glasses (8 ounces or 240 milliliters each) of water or other fluid each day, and eat a healthy diet with normal amounts of salt (sodium) as directed by your doctor or dietician while taking this medication. Large changes in the amount of salt in your diet may change your lithium blood levels. Do not change the amount of salt in your diet unless your doctor tells you to do so.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. The dosage is based on your medical condition, lithium blood levels, and response to treatment. This medication works best if the amount of the drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals.

This medication must be taken exactly as prescribed. It is important to continue taking lithium even if you feel well. Do not stop taking this drug without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Consult your doctor or pharmacist for more details.

Tell your doctor if your condition does not improve or if it worsens. It may take 1 to 3 weeks to notice improvement in your condition.

Drowsiness, dizziness, tiredness, increased thirst, increased frequency of urination, weight gain, and mildly shaking hands (fine tremor) may occur. These should go away as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: diarrhea, vomiting, fever, unsteady walk, confusion, slurred speech, blurred vision, severe hand trembling (coarse tremor), vision changes (such as growing blind spot, vision loss), joint swelling/pain, pain/discoloration of finger/toes, cold hands/feet.

Get medical help right away if you have any very serious side effects, including: severe dizziness, fainting, slow/fast/irregular heartbeat, shortness of breath, seizures.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Before taking lithium, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart disease, kidney disease, urinary problems (such as difficulty urinating), underactive thyroid (hypothyroidism), seizures, Parkinson's disease, leukemia, severe dehydration (severe loss of body water), any infection with high fever, a certain skin disorder (psoriasis).

Lithium treatment may rarely reveal an existing condition that affects the heartrhythm (Brugada syndrome). Brugada syndrome is an inherited, life-threatening heart problem that some people may have without knowing it. It can cause a serious (possibly fatal) abnormal heartbeat and other symptoms (such as severe dizziness, fainting, shortness of breath) that need medical attention right away. Brugada syndrome may cause death suddenly. Before starting lithium treatment, tell your doctor if you have any of the following risk factors: Brugada syndrome, unexplained fainting, family history of certain heart problems (Brugada syndrome, sudden unexplained death before 45 years old).

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

If heavy sweating or severe diarrhea occurs, check with your doctor right away how to best continue taking lithium. Take care in hot weather or during activities that cause you to sweat heavily such as during hot baths, saunas, or exercise.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication is not recommended for use during pregnancy. It may harm an unborn baby. However, since untreated mental/mood problems (such as bipolar disorder) can harm a pregnant woman and her unborn baby, do not stop taking this medication unless directed by your doctor. Instead, ask your doctor if a different medication would be right for you. If you are planning pregnancy, become pregnant, or think you may be pregnant, tell your doctor right away.

Lithium passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Other medications can affect the removal of lithium from your body, which may affect how lithium works. Examples include ACE inhibitors (such as captopril, enalapril), ARBs (such as losartan, valsartan), NSAIDs (such as celecoxib, ibuprofen), "water pills" (diuretics such as hydrochlorothiazide, furosemide), other drugs for mental/mood conditions (such as chlorpromazine, haloperidol, thiothixene), among others. Your doctor may need to adjust your dose of lithium if you are on these medications.

Eat a normal diet with an average amount of sodium. Consult your doctor or dietician for more details.

Follow the directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Overuse of this medicine may increase the risk of death. It is critical that you use only the prescribed dose of this medicine.

This medication comes with patient instructions for safe and effective use, and directions for priming the inhaler device. Duoneb and Combivent Respimat have different patient instructions. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

To use the inhaler (Combivent Respimat):

• You do not need to shake Combivent Respimat before use.
• Uncap the mouthpiece of the inhaler. Breathe out fully. Put the mouthpiece into your mouth and close your lips. Keep your eyes closed to prevent spraying any medicine into your eyes. Breathe in slowly while pushing down on the canister. Hold your breath for 10 seconds, then breathe out slowly.
• If you use more than one inhalation at a time, wait at least 2 minutes before using the second inhalation.
• Carefully follow all directions for cleaning your specific inhaler device once per week.

To use the solution with a nebulizer (Duoneb):

• Open the foil pouch and remove one vial. Squeeze all of the medicine out into the chamber of the nebulizer.
• Attach the mouthpiece or face mask to the drug chamber. Then, attach the drug chamber to the compressor. Sit upright in a comfortable position. Place the mouthpiece into your mouth or put the face mask on, covering your nose and mouth.
• Breathe in slowly and evenly until you have inhaled all of the medicine (usually 5 to 15 minutes). The treatment is complete when no more mist is formed by the nebulizer and the drug chamber is empty.
• Clean the nebulizer after each use. Follow the cleaning directions that came with your nebulizer.

Keep track of the number of sprays you have used. Throw away the Combivent Respimat inhaler canister after 3 months or 120 sprays, whichever comes first.

Seek medical attention if you think this medication is not working as well as usual.

While using DUONEB, you may need frequent blood tests at your doctor's office.

Use DUONEB regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store at room temperature away from moisture, heat, and light. Keep each Duoneb vial in its foil pouch until you are ready to use it. Do not store Combivent Respimat in your car on hot days. Extreme heat can cause the medicine canister to burst. Do not throw an empty canister into open flame.

Seek emergency medical attention or call the Poison Help line. An overdose of DUONEB can be fatal. Overdose symptoms may include chest pain, fast or pounding heartbeats, extreme thirst, muscle weakness or limp feeling, severe headache, buzzing in your ears, weak pulse, fainting, or slow breathing (breathing may stop).

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using DUONEB inhalation and call your doctor at once if you have:

• wheezing, choking, or other breathing problems (especially after starting a new canister of this medicine);
• chest pain, pounding heartbeats or fluttering in your chest;
• dangerously high blood pressure (severe headache, anxiety, uneven heartbeats);
• swelling of your ankles or feet;
• eye pain, or seeing halos around lights;
• painful or difficult urination; or
• low potassium (confusion, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling).

Common side effects may include:

• mild headache; or
• cold symptoms such as stuffy nose, sneezing, cough, or sore throat.

You should not use this medication if you are allergic to albuterol (Proventil, Ventolin), ipratropium (Atrovent), or atropine (Atreza, Lomotil, Vi-Atro, Sal-Tropine).

Seek medical attention if you think this medication is not working as well as usual.

You should not use this medication if you are allergic to albuterol (Proventil, Ventolin), ipratropium (Atrovent), or atropine (Atreza, Lomotil, Vi-Atro, Sal-Tropine).

To make sure DUONEB inhalation is safe for you, tell your doctor if you have:

• heart disease, high blood pressure, coronary artery disease, or heart rhythm disorder;
• a seizure disorder such as epilepsy;
• diabetes;
• overactive thyroid;
• glaucoma;
• liver or kidney disease; or
• enlarged prostate, problems with urination.

It is not known whether this medication is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether DUONEB passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using this medication.

If this medication gets in your eyes, rinse with water and seek medical attention.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Tell your doctor about all medications you use, and those you start or stop using during your treatment with DUONEB, especially:

• heart or blood pressure medication--penbutolol, pindolol, propranolol, sotalol, timolol, and others.

This list is not complete. Other drugs may interact with DUONEB, including prescription, over-the-counter, vitamin, and herbal products. Not all possible interactions are listed in this medication guide.

Read the Patient Information Leaflet if available from your pharmacist before you start taking methotrexate and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Methotrexate is a strong medication. The dosage and how often you take this medication are based on your medical condition and response to treatment. There are many different dosing schedules for this medication (especially for cancer treatment). Therefore, it is very important that you follow your doctor's instructions carefully. Take this medication by mouth as directed by your doctor.

For the treatment of psoriasis or rheumatoid arthritis, take this medication by mouthas directed by your doctor, usually once a week. It may take up to several months before you get the full benefit of this drug.

Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.

Drink plenty of fluids while taking this medication unless your doctor tells you otherwise. Doing so helps your kidneys to remove the drug from your body and avoid some of the side effects.

Nausea, vomiting, stomach pain, drowsiness, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Temporary hair loss may occur. Normal hair growth should return after treatment has ended.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mouthsores, diarrhea, signs of anemia (such as unusual tiredness, pale skin), signs of liverproblems (such as dark urine, persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin), easy bruising/bleeding, black stools, enlarged glands/lymph nodes, bone pain, unusual pain and discoloration of the skin, signs of kidney problems (such as change in the amount of urine), dry cough, muscle weakness.

Get medical help right away if you have any very serious side effects, including: weakness on one side of the body, neck stiffness, severe headache, vision changes, irregular heartbeat, mental/mood changes, seizures.

This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as fever, chills, persistent sore throat, cough).

This medication can affect sperm production, an effect that may lower male fertility. Consult your doctor for more details.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Before taking methotrexate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, lung disease (such as pulmonary fibrosis), alcohol use, suppressed immune system, blood cell/bone marrow disorders, stomach/intestinal diseases (such as peptic ulcer, ulcerative colitis), any active infection (including chickenpox or recent exposure to it), folic acid deficiency.

Methotrexate can make you more likely to get infections or may worsen any current infections. Therefore, wash your hands well to prevent the spread of infection. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.

Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccineinhaled through the nose).

To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skinblisters/redness.

Methotrexate must not be used during pregnancy. It may harm an unborn baby. It is important to prevent pregnancy during and after treatment with methotrexate. Therefore, males and females must use reliable forms of birth control (such as condoms, birth control pills) during treatment. Males should continue to use birth control for at least 3 months after the end of treatment. Females should continue to use birth control for at least 1 menstrual cycle after the end of treatment. If you become pregnant or think you may be pregnant, tell your doctor right away.

Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.

Methotrexate passes into breast milk and may harm a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: acitretin, asparaginase, chloramphenicol, leflunomide, other drugs that can cause kidney problems (such as cisplatin), other drugs that can cause liver problems (such as azathioprine, sulfasalazine, retinoids such as isotretinoin), penicillins, phenytoin, probenecid, procarbazine, pyrimethamine, sulfa medications, tetracyclines.

Certain drugs that reduce stomach acid (proton pump inhibitors-PPIs such as esomeprazole, omeprazole, pantoprazole) may increase the amount of methotrexatein your blood. This effect may increase the risk of side effects, especially with high-dose methotrexate treatment. Ask your doctor or pharmacist for details and ways to lessen the risk of side effects.

DRYSOL comes in different formulations to treat different areas of the body.

The medicine is usually used for two or three nights, until you notice results. After that, it's typically applied once or twice a week, or as directed by your doctor.

Apply DRYSOL at bedtime. For best results, the medicine should be left on your skin for six to eight hours.

Follow the instructions on the product label carefully. Don't apply more or less DRYSOL than is recommended.

Be sure to use DRYSOL on skin that's completely dry. You may need to dry your skin with a hairdryer first.

After applying DRYSOL on your underarms, you may want to wear a T-shirt to keep the medicine from rubbing off on your bedsheets.

If you're using DRYSOL on your hands or feet, you can wrap the areas in plastic and cover them with cotton gloves or socks. Don't tape the plastic onto your skin.

If you're using DRYSOL on your scalp, you can wear a plastic shower cap to keep the medicine from rubbing off on your bedsheets.

In the morning, wash or shampoo the treated areas and dry them with a towel.

DRYSOL Overdose

DRYSOL may be harmful if swallowed.

If you accidently swallow this medicine or suspect an overdose, contact a poison control center or emergency room.

Missed Dose of DRYSOL

If you miss a dose of DRYSOL and use it regularly, skip the missed dose and return to your regular dosing schedule.

Don't apply extra DRYSOL to make up for a missed dose.

Common Side Effects of DRYSOL

Tell your doctor if any of the following side effects become severe or don't go away:

• Mild itching, burning, prickling, or tingling of the treated area

Serious Side Effects of DRYSOL

Tell your doctor immediately if you experience any of the following serious side effects:

• Signs of an allergic reaction (may include hives, rash, itching, chest tightness, or swelling of the face, lips, tongue, or throat)
• Severe burning, redness, or swelling of the treated area

Talk to your doctor before using DRYSOL if you have a serious medical condition or are allergic to ingredients in the product.

Also, let your doctor know if you're taking Antabuse (disulfiram) before using DRYSOL.

Don't apply any other deodorant or antiperspirant while using DRYSOL without first talking to your doctor.

Avoid getting DRYSOL in your eyes, mouth, or nose, or on your lips. If this happens, wash the area thoroughly with water.

Don't use this medicine near an open flame. DRYSOL contains alcohol and is flammable.

Tell your healthcare provider if your symptoms don't improve, or worsen, while using this product.

Don't use this medicine on irritated or broken skin. Also, avoid using DRYSOL on areas that have recently been shaved.

DRYSOL may stain certain fabrics or metals. Keep the medicine away from surfaces that you don't want to stain.

Never share DRYSOL with others, even if they have the same symptoms as you.

Pregnancy and DRYSOL

It's not known whether DRYSOL can harm an unborn baby.

Let your doctor know if you're pregnant, or might become pregnant while using this product.

It's also not known whether DRYSOL passes into breast milk or could hurt a breastfeeding baby.

Talk to your doctor before breastfeeding while using this medicine.

Tell your doctor about all prescription, nonprescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking, especially those listed in the DRYSOL Warnings section above, and any of the following:

• Other deodorants or antiperspirants
• Flagyl (metronidazole)
• Tindamax (tinidazole)