LOVAZA comes as a liquid-filled gel capsule to take by mouth.

It's usually taken one or twice daily, with or without food.

The typical daily dose of LOVAZA is 4 grams (g) per day.

Your dose may depend on your medical condition.

Swallow the capsules whole. Don't break, crush, or chew them.

Try to take this medicine around the same time each day.

Follow the instructions on your prescription label carefully. Don't take more or less LOVAZA than is recommended.

Don't stop taking LOVAZA or change your dose without first talking to your doctor.

LOVAZA Overdose

If you suspect an overdose of LOVAZA, contact a poison control center or emergency room immediately.

Missed Dose of LOVAZA

If you miss a dose of LOVAZA, take it as soon as you remember.

But if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular medication schedule.

Don't take extra medicine to make up for a missed dose.

Common Side Effects of LOVAZA

Tell your doctor if any of the following side effects become severe or don't go away:

• Burping
• Diarrhea
• Mild heartburn
• Nausea
• Constipation
• Upset stomach or mild stomach pain
• Changes in taste

Serious Side Effects of LOVAZA

Tell your doctor right away if you experience any of the following serious side effects:

• Irregular heartbeat
• Unusual bleeding or bruising
• Signs of anaphylaxis, which may include rash, hives, itching, difficulty breathing, chest tightness, or swelling of the face, mouth, lips, or tongue

Your healthcare provider will probably recommend that you follow a specific diet and exercise plan while you're taking LOVAZA. Follow these instructions carefully.

Before starting treatment with LOVAZA, tell your doctor if you have, or have ever had:

• A blood clotting problem
• An underactive thyroid
• Liver or pancreas problems
• Diabetes
• An irregular heartbeat or another heart problem
• Allergies to medicines, fish, or soy

People with atrial fibrillation or atrial flutter (types of irregular heartbeats) may have an increased risk of experiencing an irregular heartbeat while taking LOVAZA. Talk to your doctor if this is a concern.

LOVAZA may increase your levels of low-density lipoprotein (LDL, or "bad") cholesterol.

Your doctor will want to perform frequent tests to monitor your LDL levels and to check your body's response to LOVAZA.

Keep all appointments with your doctor and laboratory.

Pregnancy and LOVAZA

It's not known whether LOVAZA could harm a fetus if taken during pregnancy.

Tell your doctor if you're pregnant, or might become pregnant, while using this medicine.

LOVAZA passes into breast milk. Don't breastfeed a baby while taking this drug without first talking with your doctor.

Tell your doctor about all prescription, nonprescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking, especially:

• Anticoagulants (blood thinners), such as Coumadin or Jantoven (warfarin)
• Antiplatelet medications, such as Pletal (cilostazol), Plavix (clopidogrel), Persantine or Aggrenox (dipyridamole), Effient (prasugrel), and ticlopidine
• Aspirin or products that contain aspirin
• Beta-blockers, such as Tenormin or Tenoretic (atenolol), Trandate (labetalol), Lopressor, Toprol XL, or Dutoprol (metoprolol), Corgard or Corzide (nadolol), and Inderal, InnoPran XL, or Inderide (propranolol)
• Diuretics (water pills)
• Estrogen-containing contraceptives (birth control pills, patches, rings, and injections)
• Estrogen replacement therapy
• Nonsteroidal anti-inflammatory drugs (NSAIDs), such as Advil or Motrin (ibuprofen) and Aleve or Naprosyn (naproxen)

LOVAZA and Alcohol

Drinking alcohol may affect your triglyceride levels.

Talk to your doctor before consuming alcoholic beverages while taking this medicine.

Usual adult dose:

Parkinson's Disease:

Take MIRAPEX in equal doses, three times daily as prescribed by your doctor. Dosages should be increased gradually from a starting dose of 0.125 mg three times daily and should not be increased more frequently than every 5 to 7 days. It is important that your doctor increases your dosage of MIRAPEX gradually to avoid side effects and to achieve the best therapeutic effect. Your dose will probably change each week until your doctor and you decide what the best dose is for you. Make sure that you only use the tablet strength that your doctor has prescribed. The maximal recommended dose of MIRAPEX is 4.5 mg per day. Lower doses are recommended for patients with kidney disease.

Your doctor may decide to lower your dose of levodopa to prevent excessive side effects and to make sure that you are getting the best results from both drugs. Pay close attention to your doctor's instructions and never change the dose of either drug yourself.

You should not change the dose or discontinue treatment with MIRAPEX without the recommendation of your doctor.

You may take MIRAPEX without food or with food if you find that you feel sick to your stomach while taking the tablets.

Restless Legs Syndrome:

The recommended starting dose of MIRAPEX is 0.125 mg taken once daily (2-3 hours before bedtime) as prescribed by your doctor. If it is required, your doctor may change the dose every 4-7 days to achieve the best therapeutic effect. Tablets should be swallowed with water, and can be taken either with or without food. The maximal recommended dose of MIRAPEX is 0.50 mg per day.

Do not stop taking MIRAPEX suddenly, as this may result in worsened RLS symptoms. Talk to your doctor about slowly stopping the medication if necessary.

Overdose:

If you accidentally take too many tablets, you should get medical help immediately; either by calling your doctor, the regional Poison Control centre or by going to the nearest hospital (do not drive yourself). Always take the labelled medicine container with you whether or not there are any MIRAPEX tablets left.

Missed dose:

If you forget to take a dose, take it as soon as you remember, then carry on as before. However, if it is almost time for your next dose, skip the dose you missed and take the next dose when you are supposed to. Do not take more than one dose at a time.

MIRAPEX has been prescribed for you. Do not give these tablets to anyone else, even if you think they have the same condition as you.

You should be aware that prescription medicines carry some risks and that all possible risks may not be known at this stage. Discuss with your doctor the risks of taking MIRAPEX against the expected benefits.

If you do experience any unusual or unwanted effects while you are taking MIRAPEX, be sure to tell your doctor. It is important that he/she knows of any unwanted effects to determine the best dose of MIRAPEX for you.

• MIRAPEX may cause unwanted effects such as nausea, constipation, sleepiness, dizziness, dream abnormalities, amnesia (memory loss), fatigue, muscle weakness, restlessness, weight decrease, including decreased appetite, weight increased, hiccups, accidental injury, confusion, pneumonia, abnormal behaviour (reflecting symptoms of impulse control disorders and compulsions), overeating, headache, hyperkinesia (unusually overactive), fainting, visual impairment, including double vision, vision blurred and visual acuity reduced, shortness of breath, vomiting, heart failure, and peripheral oedema (swelling of hands, ankles or feet).
• MIRAPEX does not usually affect people's normal activities. However, some people may feel dizzy or sleepy while takingMIRAPEX, especially during the first few weeks of treatment.
• If you are taking MIRAPEX for RLS you may notice an increase in your symptoms in the early morning or the afternoon/early evening hours. If this happens, please, let your doctor know.

You are warned of a sudden onset of sleep condition which may occur without warning, while taking MIRAPEX. You should not drive, operate machinery or engage in activities that require alertness, as you may put yourself and others at risk of serious injury or death. This sudden onset of sleep condition has also been reported in patients taking other anti-Parkinson drugs of the same class.

Studies of people with Parkinson's disease show that they may be at an increased risk of developing melanoma (a form of skin cancer) when compared to people without Parkinson's disease. It is not known if this problem is associated with Parkinson's disease or the drugs used to treat Parkinson's disease. MIRAPEX is one of the drugs used to treat Parkinson's disease; therefore, patients treated with MIRAPEX should have periodic skin examinations.

Patients and caregivers should be aware of the fact that abnormal behavior such as pathological gambling, increased sexual desire, excessive sexual activity, compulsive shopping or binge eating have been reported. Those changes have also been reported in patients taking other anti-Parkinson drugs of the same class.

BEFORE you use MIRAPEX talk to your doctor or pharmacist:

• if you have any health problems, especially kidney problems or blood pressure problems;
• if you have any unusual conditions related to your eyes or eyesight;
• if you have previously taken MIRAPEX and became unwell;
• if you have any allergies or reactions to foods or drugs;
• if you are pregnant or intend to become pregnant;
• if you are breast feeding;
• if you are taking any other medications, including any drugs you can buy without a prescription;
• if you drive a vehicle or perform hazardous tasks during your work.

Other medications may be affected by MIRAPEX or may affect how MIRAPEX works. Do not take any other medication, including over-the-counter medications or herbal products unless your doctor tells you to. Tell any other doctor, dentist or pharmacist that you talk to that you are taking MIRAPEX.

Avoid alcohol or other sedatives while taking MIRAPEX.

Side effects may include:

• dizziness;

• drowsiness, fatigue, weakness;

• cough (dry, non-productive, mainly at night, continuing);

• sore throat and throat irritation;

• headache;

• abdominal pain; pain in your muscles, back or bones;

• rash, itching, increased sensitivity of the skin to sun, flushing;

• diarrhea, constipation, vomiting, nausea, stomach upset;

• numbness or tingling in the hands, feet or lips;

• ringing in the ears;

• loss of taste;

• erectile dysfunction;

If any of these affects you severely, tell your doctor, nurse or pharmacist.

LOTENSIN can cause abnormal blood test results. Your doctor will decide when to perform blood tests and will interpret the results.

Serious Warnings and Precautions—Pregnancy

LOTENSIN should not be used during pregnancy. If you discover that you are pregnant while taking LOTENSIN, stop the medication and contact your doctor, nurse, or pharmacist as soon as possible.

As with most medicines, interactions with other drugs are possible. Tell your doctor, nurse, or pharmacist about all the medicines you take, including drugs prescribed by other doctors, vitamins, minerals, natural supplements, or alternative medicines.

The following may interact with LOTENSIN:

• Agents increasing serum potassium, such as a salt substitute that contains potassium, potassium supplements, or a potassium-sparing diuretic (a specific kind of “water pill”).

• Alcohol as it may make blood pressure fall more and/or increase the possibility of dizziness or fainting.

• Antidiabetic drugs, including insulin, oral medicines and dipeptidyl peptide-IV inhibitors.

• Gout medications, including allopurinol and probenecid.

• Lithium used to treat bipolar disease and other psychological conditions.

• Nonsteroidal anti-inflammatory drugs (NSAIDs), used to reduce pain and swelling. Examples include ibuprofen, naproxen, indomethacin and celecoxib.

• Other blood pressure lowering drugs, including diuretics (“water pills”), angiotensin receptor blockers (ARBs) or aliskiren-containing products (e.g. RASILEZ).

• Cyclosporine, an immunosuppressant medicine used in transplanted patients to reduce the risk of organ rejection.

• Heparin, an anticoagulant medicine used to prevent or treat blood clots.

• Erythropoietin, a medicine used to regulate the production of red blood cells.

• Gold for the treatment of rheumatoid arthritis.

• Medicine used to treat some cancers and also some non-cancerous growths associated with a genetic disorder (e.g. temsirolimus, sirolimus, everolimus).

Read the Medication Guide provided by your pharmacist before you start using etodolac and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually 2 or 3 times a day with a full glass of water (8 ounces/240 milliliters). Do not lie down for at least 10 minutes after taking this drug. To prevent stomach upset, take this medication with food, milk, or an antacid.

The dosage is based on your medical condition and response to treatment. To reduce your risk of stomach bleeding and other side effects, take this medication at the lowest effective dose for the shortest possible time. Do not increase your dose or take it more often than directed. For ongoing conditions such as arthritis, continue taking this medication as directed by your doctor.

If you are taking this drug "as needed" (not on a regular schedule), remember that pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.

For certain conditions (such as arthritis), it may take up to two weeks of taking this drug regularly until you get the full benefit.

Tell your doctor if your condition does not improve or if it worsens.

Upset stomach, nausea, diarrhea, drowsiness, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.

Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, difficult/painful swallowing, hearing changes (such as ringing in the ears), mental/mood changes, swelling of the ankles/feet/hands, sudden/unexplained weight gain, signs of kidney problems (such as change in the amount of urine), unexplained stiff neck, vision changes, unusual tiredness.

This drug may rarely cause serious (possibly fatal) liver disease. Get medical help right away if you have any symptoms of liver damage, including: dark urine, persistent nausea/vomiting/loss of appetite, stomach/abdominal pain, yellowing eyes/skin.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Before taking etodolac, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs (such as ibuprofen, naproxen, celecoxib); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before taking this medication, tell your doctor or pharmacist your medical history, especially of: asthma (including a history of worsening breathing after taking aspirinor other NSAIDs), blood disorders (such as anemia, bleeding/clotting problems), growths in the nose (nasal polyps), heart disease (such as previous heart attack), high blood pressure, liver disease, stroke, throat/stomach/intestinal problems (such as bleeding, heartburn, ulcers).

Kidney problems can sometimes occur with the use of NSAID medications, including etodolac. Problems are more likely to occur if you are dehydrated, have heart failureor kidney disease, are an older adult, or if you take certain medications (see also Drug Interactions section). Drink plenty of fluids as directed by your doctor to prevent dehydration and tell your doctor right away if you have a change in the amount of urine.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.

This medicine may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Limit alcohol and stop smoking. Consult your doctor or pharmacist for more information.

This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skinblisters/redness.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially stomach/intestinal bleeding, kidney problems, and worsening heart problems.

Before using this medication, women of childbearing age should talk with their doctor(s) about the benefits and risks (such as miscarriage, trouble getting pregnant). Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, this medication should be used only when clearly needed. It is not recommended for use during the first and last trimesters of pregnancy due to possible harm to the unborn baby and interference with normal labor/delivery.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Products that may interact with this drug include: aliskiren, ACE inhibitors (such as captopril, lisinopril), angiotensin II receptor blockers (such as losartan, valsartan), cidofovir, corticosteroids (such as prednisone), lithium, "water pills" (diuretics such as furosemide).

This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Examples include anti-platelet drugs such as clopidogrel, "blood thinners" such as dabigatran/enoxaparin/warfarin, among others.

Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs such as celecoxib, ibuprofen, or ketorolac). These drugs are similar to etodolac and may increase your risk of side effects if taken together. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually at dosages of 81-325 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

This medication may affect certain laboratory tests, possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

BEFORE you use LODALIS talk to your doctor or pharmacist if:

• your triglyceride levels (a blood fat) are greater than 3.4 mmol/L
• you have difficulty in swallowing, or have a major stomach or intestinal disorder
• you are taking another medication called cyclosporine (a medicine used to suppress the immune system)
• you are taking antidiabetic treatments
• you are taking the oral contraceptive pill
• you are taking anticoagulant therapy
• you suffer from constipation, as LODALIS may induce or worsen this condition. This is especially important for patients with coronary heart disease and angina pectoris
• you are pregnant, planning on becoming pregnant or are breastfeeding
• you have any allergies to this drug or its ingredients or components of the container

Like all medicines, LODALIS can cause side effects, although not everybody gets them.

The following side effects have been reported in patients taking LODALIS: constipation, flatulence (gas), diarrhea, indigestion, muscle pain, abdominal pain, abnormal stools, feeling sick (nausea), headache, raised levels of triglycerides (fats) in your blood, raised levels of liver enzymes in your blood. You may notice that hemorrhoids get worse.

Side effects were usually mild or moderate in intensity.

To ensure that the effectiveness of the following medications is not affected, it is important that you take the following medications at least 4 hours before taking LODALIS.

Drugs that may interact with LODALIS include:

• Anticoagulant therapy (medicines, such as warfarin, used to thin blood)
• Thyroid replacement therapy (medicines, such as thyroxine or levothyroxine, used to treat low thyroid hormone levels)
• Oral contraceptives (medicines to prevent pregnancy)
• Verapamil (a medicine used to treat high blood pressure)
• Antidiabetic medications (medicines, such as pioglitazone, repaglinide, glyburide, metformin and insulin used to treat diabetes)
• Anti-epileptic medicines (medicines, such as phenytoin, used to treat epilepsy)
• Cyclosporine (a medicine used to suppress the immune system).

If you are going to take LODALIS and one of these medicines, your doctor may want to do tests to make sure that LODALIS does not interfere with these medicines.

Additionally, if you have any condition that could cause you to have a deficiency of vitamins A, D, E or K, your doctor may want to check your vitamin levels periodically while you are taking LODALIS. If necessary, your doctor may advise you to take vitamin supplements.

Before starting therapy with LODALIS, you should be advised to follow a cholesterol-lowering diet and you should continue this diet during treatment.

Take LODALIS with a meal.

Usual dose:

Monotherapy:

The usual starting dose for LODALIS is 3 tablets taken twice a day with meals or 6 tablets a day with a meal. Your doctor may increase your dose to a maximum of 7 tablets per day. The usual dose of LODALIS powder for oral suspension is one packet (3.75 g of colesevelam resin) a day with a meal.

Combination therapy:

The usual dose for LODALIS, when used with a statin, is 4 to 6 tablets a day. The maximum recommended dose is 6 tablets per day. Your doctor may tell you to take the LODALIS dose either once a day or twice a day. The usual dose of LODALIS powder for oral suspension when used with a statin is one packet (3.75 g of colesevelam resin) a day with a meal. LODALIS should be taken with a meal. The dosing of the statin should follow the instructions for that particular statin. The two medicines may be taken at the same time or at separate times according to what your doctor has prescribed.

Overdose:

Please contact your doctor. Constipation or bloating could occur.

In case of drug overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.

Missed dose:

You may take a missed dose with a later meal, but do not take a double dose of LODALIS to make up for missed doses.

There are different brands of this medication available. They may not have the same effects. Do not change brands without asking your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually 2-3 times daily. Take lithium with or immediately after meals to lessen stomach upset. Do not crush or chew this medication. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

Drink 8 to 12 glasses (8 ounces or 240 milliliters each) of water or other fluid each day, and eat a healthy diet with normal amounts of salt (sodium) as directed by your doctor or dietician while taking this medication. Large changes in the amount of salt in your diet may change your lithium blood levels. Do not change the amount of salt in your diet unless your doctor tells you to do so.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. The dosage is based on your medical condition, lithium blood levels, and response to treatment. This medication works best if the amount of the drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals.

This medication must be taken exactly as prescribed. It is important to continue taking lithium even if you feel well. Do not stop taking this drug without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Consult your doctor or pharmacist for more details.

Tell your doctor if your condition does not improve or if it worsens. It may take 1 to 3 weeks to notice an improvement in your condition.

Drowsiness, dizziness, tiredness, increased thirst, increased frequency of urination, weight gain, and mildly shaking hands (fine tremor) may occur. These should go away as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: diarrhea, vomiting, fever, unsteady walk, confusion, slurred speech, blurred vision, severe hand trembling (coarse tremor), vision changes (such as growing blind spot, vision loss), joint swelling/pain, pain/discoloration of finger/toes, cold hands/feet.

Get medical help right away if you have any very serious side effects, including: severe dizziness, fainting, slow/fast/irregular heartbeat, shortness of breath, seizures.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before taking lithium, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart disease, kidney disease, urinary problems (such as difficulty urinating), underactive thyroid (hypothyroidism), seizures, Parkinson's disease, leukemia, severe dehydration (severe loss of body water), any infection with high fever, a certain skin disorder (psoriasis).

Lithium treatment may rarely reveal an existing condition that affects the heartrhythm (Brugada syndrome). Brugada syndrome is an inherited, life-threatening heart problem that some people may have without knowing it. It can cause a serious (possibly fatal) abnormal heartbeat and other symptoms (such as severe dizziness, fainting, shortness of breath) that need medical attention right away. Brugada syndrome may cause death suddenly. Before starting lithium treatment, tell your doctor if you have any of the following risk factors: Brugada syndrome, unexplained fainting, family history of certain heart problems (Brugada syndrome, sudden unexplained death before 45 years old).

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

If heavy sweating or severe diarrhea occurs, check with your doctor right away how to best continue taking lithium. Take care in hot weather or during activities that cause you to sweat heavily such as during hot baths, saunas, or exercise.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication is not recommended for use during pregnancy. It may harm an unborn baby. However, since untreated mental/mood problems (such as bipolar disorder) can harm a pregnant woman and her unborn baby, do not stop taking this medication unless directed by your doctor. Instead, ask your doctor if a different medication would be right for you. If you are planning pregnancy, become pregnant, or think you may be pregnant, tell your doctor right away.

Lithium passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Other medications can affect the removal of lithium from your body, which may affect how lithium works. Examples include ACE inhibitors (such as captopril, enalapril), ARBs (such as losartan, valsartan), NSAIDs (such as celecoxib, ibuprofen), "water pills" (diuretics such as hydrochlorothiazide, furosemide), other drugs for mental/mood conditions (such as chlorpromazine, haloperidol, thiothixene), among others. Your doctor may need to adjust your dose of lithium if you are on these medications.

Eat a normal diet with an average amount of sodium. Consult your doctor or dietician for more details.

This medication is given by injection into the space around the spinal cord (intrathecally). It is usually given using a drug pump implanted under your skin. A health care professional will fill and refill the pump with medication.

The dosage is based on your medical condition and response to treatment.

If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.

Do not stop treatment with this drug without consulting your doctor because serious withdrawal symptoms may occur. See also Warning section. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away.

When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.

Tell your doctor if your condition does not improve or if it worsens, or if you have any signs of infection (such as fever, chills, redness/swelling/pain/warmth at the pump site).

Drowsiness, dizziness, weakness, headache, constipation, nausea, or vomiting may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as confusion, depression, hallucinations), numb/tingling skin, vision changes, difficulty urinating.

Get medical help right away if you have any very serious side effects, including: seizures, trouble breathing.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before using baclofen, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: recent/current infection, seizures, mental/mood disorders (such as schizophrenia), kidney disease.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), other muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.