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A generic alternative to Neupro is currently not available on the market.
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Neupro (Rotigotine): Product Overview
Neupro is a prescription medication offered in the form of skin patches. It is made for Parkinson’s disease and for those that suffer from Restless Legs Syndrome .
Neupro is manufactured by UCB in Canada and we offer it in these doses: 1mg/24 hour, 2mg/24 hour, 3mg/24 hour, 4mg/24 hour, 6mg/24 hour and 8mg/24 hour. We also have this prescription drug available from the United Kingdom manufactured by UCB Pharma Ltd.
There are 30 patches in a box, which typically will cover a month supply; therefore, 90 patches (3 boxes x 30 patches) is the typical 3-month supply ordered.
Neupro (Rotigotine Transdermal System) Medication Information
Neupro is a prescription skin patch used in adults to treat one of two different medical conditions: Parkinson’s Disease or moderate to severe Restless Leg Syndrome.
Parkinson’s Disease is a progressive disease of the nervous system, including the brain and nerves. There’s no cure for Parkinson’s Disease, and its exact cause is unknown. Experts think that people with Parkinson’s may have low levels of dopamine. Dopamine is a chemical messenger that works in the brain to help control the body’s movements.
Parkinson’s Disease symptoms usually start on one side of the body and spread to both sides over time. Symptoms can vary, but may include:
- Bradykinesia (slowness of movements)
- Muscle stiffness
- Tremor (shaking)
- Trouble with balance
- Loss of fine motor control (such as buttoning a shirt)
- Decreased facial expression
Restless Leg Syndrome (RLS) is a disorder defined by an uncontrollable urge to move the legs while trying to relax or sleep. People with RLS may get this urge to move their legs every 30 seconds while lying down. This urge is sometimes relieved by getting up, walking around, and stretching the legs. As a result, people with RLS usually don’t get enough sleep and experience daytime fatigue (lack of energy).
Neupro isn’t a cure for Parkinson’s Disease or Restless Leg Syndrome. But, it can help improve movement-related symptoms and can improve your ability to perform daily activities.
Neupro is a prescription patch that comes in six different strengths:
- 1 mg/24 hours
- 2 mg/24 hours
- 3 mg/24 hours
- 4 mg/24 hours
- 6 mg/24 hours
- 8 mg/24 hours
Each Neupro patch delivers the active ingredient, rotigotine, through the skin over 24 hours. It’s changed once per day and should be pressed firmly in place for 30 seconds.
Your doctor may increase or decrease your strength of Neupro patch over time. To learn how to apply Neupro patch, see this helpful video.
Neupro patch may not be safe for everyone with Parkinson’s Disease or Restless Leg Syndrome. Let your doctor know if you have any of the following conditions or concerns:
- Allergy to sulfites or any ingredient of Neupro patches
- Hallucinations/psychosis (seeing or hearing things that aren’t there)
- High blood pressure or heart disease
- Problems with postural hypotension (dizziness when moving from sitting or laying down to standing)
Neupro treatment should not be stopped suddenly. Suppose the Neupro patch is removed, and a new patch isn’t applied. In that case, harmful effects may happen, such as hyperpyrexia and confusion. Hyperpyrexia is an extremely high fever that requires emergency medical care and may lead to death. If you are worried about your ability to remember to replace your patch daily, talk to your doctor about the risks and benefits of the Neupro patch.
Like all medications, Neupro patch can cause side effects in some people. The most common side effects in people who used Neupro in clinical studies were:
- Insomnia (trouble falling or staying asleep)
- Daytime sleepiness
- Skin irritation where patch is applied
This is not a complete list of all possible side effects from Neupro. If you have any questions about the risks of Neupro, talk to your doctor or pharmacist.
Certain medications can prevent Neupro from working effectively. A few examples include:
- Clozaril (clozapine)
- Invenga (paliperidone)
- Phenergan (promethazine)
- Reglan (metoclopramide)
- Risperdal (risperidone)
- Seroquel (quetiapine)
Before starting any new over-the-counter medicines or natural supplements while taking Neupro, consult with your doctor or pharmacist.
Store Neupro patches in their sealed pouches at room temperature (20º to 25ºC; 68º to 77ºF).
- It’s possible that Neupro could make you feel sleepy, especially when you first start using it. Do not drive, operate heavy machinery, or do other potentially dangerous activities until you know how this medication affects you.
- Please Neupro patch on clean, dry, non-broken skin. Avoid placing the patch on areas that will be rubbed by tight clothing. Choose a different site for your patch each day when you change it, and don’t use the same exact site more than once every 2 weeks.
What should I do if my Neupro patch becomes loose or falls off?
Neupro patch might become loose after bathing or swimming. If this occurs, you can tape down the edges with bandaging tape. If your patch falls off, apply a new patch. The next day, apply a
new patch at your regular time. There is no need to adjust your patch-changing schedule.
Is there anything I need to avoid while using the Neupro patch?
You should avoid anything that will produce heat onto the site of the Neupro patch on your skin. Some examples include heating pads, saunas, hot tubs, and direct sunlight. Neupro patch shouldn’t be worn during certain medical procedures because the patch could burn your skin. If you need medical procedures such as an MRI, talk to your doctor.
- Mansur A, Castillo PR, Rocha Cabrero F, et al. Restless Leg Syndrome. StatPearls. Treasure Island, FL; StatPearls Publishing: 2020. https://www.ncbi.nlm.nih.gov/books/NBK430878/ Accessed January 28, 2021.
- Neupro Prescribing Information. Smyrna, GA; UCB, Inc.: 2020. https://www.neupro.com/neupro-prescribing-information.pdf Accessed January 24, 2021.
- Zafar S, Yaddanapudi SS. Parkinson Disease. StatPearls. Treasure Island, FL; StatPearls Publishing: 2020. https://www.ncbi.nlm.nih.gov/books/NBK470193/ Accessed January 28, 2021.
Author: Dr. Patricia Weiser, PharmD
Patricia Weiser, PharmD, is a licensed pharmacist and medical writer. She has clinical experience in community and hospital pharmacy. Patricia is a 2007 graduate of the University of Pittsburgh. She resides in Pennsylvania with her husband and two daughters.
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.