Lotensin (Benazepril)

(℞) Prescription Required

    Lotensin (Benazepril) Dosage and Side Effects

    LOTENSIN lowers high blood pressure. LOTENSIN is an angiotensin converting enzyme (ACE) inhibitor.

    Proper Use of this medication

    Take LOTENSIN exactly as prescribed. It is recommended to take your dose at about the same time every day.

    You can take LOTENSIN before, during or after a meal since food will not decrease its effectiveness. Swallow your tablet with a glass of water.

    The dose of LOTENSIN must be individualized. Your doctor will prescribe the lowest possible dose for your needs, to be taken once or twice a day. Your doctor will tell you exactly how many tablets of LOTENSIN to take. Depending on how you respond to the treatment, your doctor may suggest a higher or lower dose. Do not exceed the recommended dose. Never change the dose unless told to do so.

    Usual Adult Dose:

    Recommended Initial Dose: 10 mg a day.

    Usual Maintenance Dose: 20 mg a day.

    Maximum Dose: 40 mg a day.

    In patients with severe kidney disease: Recommended Initial Dose: 5 mg a day.


    If you think you have taken too much LOTENSIN contact your doctor, nurse, pharmacist, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.

    Missed dose:

    If you miss a dose of this medicine, take the missed dose as soon as possible. If it is almost time for your next dose, skip the missed dose and then take the next one at the usual time. Do not take a double dose on the next day to make up for the forgotten tablet(s).

    Side Effects

    Side effects may include:

    • dizziness;

    • drowsiness, fatigue, weakness;

    • cough (dry, non-productive, mainly at night, continuing);

    • sore throat and throat irritation;

    • headache;

    • abdominal pain; pain in your muscles, back or bones;

    • rash, itching, increased sensitivity of the skin to sun, flushing;

    • diarrhea, constipation, vomiting, nausea, stomach upset;

    • numbness or tingling in the hands, feet or lips;

    • ringing in the ears;

    • loss of taste;

    • erectile dysfunction;

    If any of these affects you severely, tell your doctor, nurse or pharmacist.

    LOTENSIN can cause abnormal blood test results. Your doctor will decide when to perform blood tests and will interpret the results.

    Warnings and Precautions

    Serious Warnings and Precautions—Pregnancy

    LOTENSIN should not be used during pregnancy. If you discover that you are pregnant while taking LOTENSIN, stop the medication and contact your doctor, nurse, or pharmacist as soon as possible.

    BEFORE you use LOTENSIN talk to your doctor, nurse or pharmacist if you:

    • Are allergic to any drug used to lower blood pressure.

    • Have recently received or are planning to get allergy shots for bee or wasp stings.

    • Have narrowing of an artery or a heart valve.

    • Have had a heart attack or stroke.

    • Have heart failure.

    • Have liver or kidney disease.

    • Have diabetes.

    • Are dehydrated or suffer from excessive vomiting, diarrhea, or sweating.

    • Are on dialysis.

    • Are taking a salt substitute that contains potassium, potassium supplements, or a potassium-sparing diuretic (a specific kind of “water pill”).

    • Are on a low-salt diet.

    • Are receiving gold (sodium aurothiomalate) injections.

    • Are less than 18 years old.

    • Have collagen vascular diseases. Collagen vascular diseases are (diseases in which the body reacts against its own tissues, often causing joint pain and inflammation). Examples are systemic lupus erythematosus or scleroderma.

    • Are taking a medicine that contains aliskiren, such as RASILEZ, used to lower high blood pressure. The combination with LOTENSINis not recommended.

    • Are taking an angiotensin receptor blocker (ARB). You can recognize an ARB because its medicinal ingredient ends in “-SARTAN”.

    • Are taking medicine to treat some cancer and non-cancerous growths associated with genetic disorders ((e.g. temsirolimus, sirolimus, everolimus).

    You may become sensitive to the sun while taking LOTENSIN Exposure to sunlight should be minimized until you know how you respond.

    If you are going to have surgery and will be given an anesthetic, be sure to tell your doctor or dentist that you are taking LOTENSIN.

    Driving and using machines:

    Before you perform tasks which may require special attention, wait until you know how you respond to LOTENSIN. Dizziness, lightheadedness, or fainting can occur. Take care especially after the first dose and when the dose is increased.

    Interactions with this medication

    As with most medicines, interactions with other drugs are possible. Tell your doctor, nurse, or pharmacist about all the medicines you take, including drugs prescribed by other doctors, vitamins, minerals, natural supplements, or alternative medicines.

    The following may interact with LOTENSIN:

    • Agents increasing serum potassium, such as a salt substitute that contains potassium, potassium supplements, or a potassium-sparing diuretic (a specific kind of “water pill”).

    • Alcohol as it may make blood pressure fall more and/or increase the possibility of dizziness or fainting.

    • Antidiabetic drugs, including insulin, oral medicines and dipeptidyl peptide-IV inhibitors.

    • Gout medications, including allopurinol and probenecid.

    • Lithium used to treat bipolar disease and other psychological conditions.

    • Nonsteroidal anti-inflammatory drugs (NSAIDs), used to reduce pain and swelling. Examples include ibuprofen, naproxen, indomethacin and celecoxib.

    • Other blood pressure lowering drugs, including diuretics (“water pills”), angiotensin receptor blockers (ARBs) or aliskiren-containing products (e.g. RASILEZ).

    • Cyclosporine, an immunosuppressant medicine used in transplanted patients to reduce the risk of organ rejection.

    • Heparin, an anticoagulant medicine used to prevent or treat blood clots.

    • Erythropoietin, a medicine used to regulate the production of red blood cells.

    • Gold for the treatment of rheumatoid arthritis.

    • Medicine used to treat some cancers and also some non-cancerous growths associated with a genetic disorder (e.g. temsirolimus, sirolimus, everolimus).

    Other related products

    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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