Cafergot Tablets (Caffeine/Ergotamine) Dosage and Side Effects
CAFERGOT is a combination of Caffeine and Ergotamine. CAFERGOT is a medicine used to treat or prevent a migraine type headache. This medication will only treat a headache that has already begun. It will not prevent migraine headaches or reduce the number of attacks.
Proper Use of this medication
Follow all directions on your prescription label. Never use more than your recommended dose. Overuse of migraine headache medicine can make headaches worse. Tell your doctor if the medicine seems to stop working as well in treating your migraine attacks. This medicine is not for daily use.
To use CAFERGOT tablets:
•Take 2 tablets of CAFERGOT as soon as you notice headache symptoms, or after an attack has already begun.
•If your headache does not completely go away, you may take 1 more tablet after at least 30 minutes have passed.
•If additional medication is needed, you may take 1 tablet every 30 minutes up to a total of 6 tablets for one migraine attack.
If you still have migraine symptoms after taking a total of 6 tablets, call your doctor. Do not take more than a total of 6 tablets in any 24-hour period. Do not take more than a total of 10 tablets over a period of 7 days.
Do not take a rectal suppository by mouth. It is for use only in your rectum.
Wash your hands before and after inserting the rectal suppository.
To use CAFERGOT rectal suppositories:
•Insert 1 suppository at the first sign of migraine headache symptoms, or after an attack has already begun.
•Remove the wrapper before inserting the suppository. Avoid handling the suppository too long or it will melt in your hands.
•Lie on your back with your knees up toward your chest. Gently insert the suppository into your rectum about 1 inch.
•For best results, stay lying down for a few minutes. The suppository will melt quickly and you should feel little or no discomfort while holding it in. Avoid using the bathroom just after using the suppository.
•If your headache does not completely go away, use 1 more suppository after at least 1 hour has passed.
If you still have migraine symptoms after using a total of 2 rectal suppositories, call your doctor. Do not use more than a total of 2 suppositories per headache. Do not use more than a total of 5 suppositories over a period of 7 days.
Do not share this medication with another person, even if they have the same symptoms you have.
Store at room temperature away from moisture and heat.
Seek emergency medical attention if you think you have used too much of this medicine. An overdose of CAFERGOT can be fatal.
Since CAFERGOT is used only when needed, you are not likely to miss a dose.
Do not take more than 6 CAFERGOT tablets per day or more than 10 tablets per week.
Do not use more than 2 suppositories per headache or 5 suppositories per week.
Warnings and Precautions
CAFERGOT should not be used to treat common tension headaches or any headache that seems to be different from your usual migraine headaches.
CAFERGOT may also be used for purposes not listed in this medication guide.
This medication can harm an unborn baby or cause birth defects. Do not use if you are pregnant.
You should not use CAFERGOT if you have coronary heart disease, high blood pressure, circulation problems, liver or kidney disease, or a serious infection called sepsis.
Some medicines can cause a dangerous decrease in blood flow when used with CAFERGOT. A severe decrease in blood flow to the brain and other parts of the body can lead to dangerous side effects.
Tell your doctor about all medicines you use, and those you start or stop using, especially: atazanavir, boceprevir, clarithromycin, delavirdine, fosamprenavir, imatinib, indinavir, isoniazid, itraconazole, ketoconazole, nefazodone, nelfinavir, nicardipine, posaconazole, quinidine, ritonavir, saquinavir, telaprevir, telithromycin, or voriconazole.
You should not use this medicine if you are allergic to caffeine or ergotamine, if you are pregnant, or if you have:
•coronary heart disease;
•high blood pressure;
•blood circulation problems;
•kidney disease; or
•a serious infection called sepsis.
Some medicines can cause a dangerous decrease in blood flow when used with CAFERGOT. A severe decrease in blood flow to the brain and other parts of the body can lead to dangerous side effects. Your doctor may need to change your treatment plan if you use any of the following drugs:
•an antibiotic--clarithromycin, telithromycin;
•antifungal medication--itraconazole, ketoconazole, posaconazole, voriconazole;
•heart medication--nicardipine, quinidine;
•hepatitis C medications--boceprevir, telaprevir; or
•HIV/AIDS medication--atazanavir, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir.
FDA pregnancy category X. This medication can harm an unborn baby or cause birth defects. Do not use CAFERGOT if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use effective birth control while you are using this medication.
CAFERGOT can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using CAFERGOT and call your doctor at once if you have:
•weak pulses in your arms and legs, numbness and tingling or pain in your hands or feet, blue-colored fingers or toes;
•painful sores on your rectum after using the rectal suppositories;
•sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
•fast or slow heart rate;
•leg weakness, muscle pain in your arms or legs;
•severe pain in your stomach or lower back;
•little or no urinating;
•chest discomfort, dry cough or hack, feeling short of breath on exertion; or
•dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).
Common side effects may include:
•dizziness, spinning sensation;
•nausea, vomiting; or
•mild itching or swelling.
Interactions with this medication
Do not use CAFERGOT within 24 hours before or after using another migraine headache medicine, including:
•dihydroergotamine, ergonovine, or methylergonovine; or
•almotriptan, eletriptan, frovatriptan, naratriptan, sumatriptan, rizatriptan, or zolmitriptan.
Grapefruit and grapefruit juice may interact with CAFERGOT and lead to unwanted side effects. Avoid the use of grapefruit products while taking CAFERGOT.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with CAFERGOT, especially:
•an antibiotic--ciprofloxacin, doxycycline, erythromycin, metronidazole, norfloxacin, tetracycline;
•antifungal medication--clotrimazole, fluconazole, voriconazole;
•an antidepressant--desipramine, fluoxetine, fluvoxamine, sertraline;
•diet pills, stimulants, or ADHD medication;
•heart or blood pressure medication--amiodarone, diltiazem, dronedarone, lidocaine, propranolol, verapamil;
•HIV/AIDS medication--atazanavir, fosamprenavir, efavirenz, darunavir when given with ritonavir, saquinavir; or
•medicines to treat asthma, colds or allergies.
This list is not complete. Other drugs may interact with CAFERGOT, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.