Uloric (Febuxostat)

Generic equivalent: Febuxostat
Alternative name(s): Adenuric

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    Uloric (febuxostat) Dosage and Side Effects

    ULORIC is used to lower uric acid levels in adult patients with gout.

    Warnings and Precautions

    ULORIC treatment should only be started when the acute attack of gout has subsided.

    Whenever you start medicines that can lower uric acid levels, like ULORIC, gout may flare up. This is due to the body's efforts to get rid of uric acid crystals from the joints. However over time, reducing your uric acid level can decrease your gout flares. Your healthcare professional may add other medicines to help prevent or manage flares while taking ULORIC.

    A very small number of heart attacks, strokes and heart-related deaths have been reported. You should not use ULORIC if you have heart problems, such as heart failure or have had a stroke or heart attack.

    Mild increases in liver function tests were reported in some patients taking ULORIC. Your healthcare professional may do blood tests to check your liver function.

    Some serious skin and allergic reactions such as rash, skin reddening, pain, swelling or blistering of lips, eyes or mouth, skin peeling and flu-like symptoms have been reported in patients taking ULORIC. If you get these symptoms, your doctor may stop your treatment until your skin condition improves. Patients who had previous reactions to allopurinol are at greater risk for these skin conditions.

    BEFORE you use ULORIC talk to your doctor or pharmacist if you:

    • have a history of liver or kidney problems.
    • have heart disease, heart problems or had a stroke.
    • are pregnant, breastfeeding or plan to become pregnant, or plan to breast-feed. It is not known if ULORIC will harm your unborn baby. It is also unknown if ULORIC passes into your breast milk.

    It is not known if ULORIC is safe and effective in children under 18 years of age.

    Side Effects

    The most common side effects of ULORIC include:

    • liver problems
    • diarrhea
    • rash
    • nausea
    • dizziness

    Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

    Interactions with this medication

    Do not take ULORIC if you take:

    • azathioprine
    • mercaptopurine

    Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. ULORIC may affect the way other medicines work, and other medicines may affect how ULORIC works.

    Know the medicines you take. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine.

    Proper Use of this medication

    Usual adult dose:

    The recommended dose of ULORIC is one 80 mg tablet once daily.

    • Take ULORIC exactly as your healthcare provider tells you to take it.
    • ULORIC can be taken with or without food.
    • ULORIC can be taken with antacids.
    • It is important not to stop taking your ULORIC without first consulting with your healthcare provider even if you have a flare.
    • Your healthcare provider may do certain tests while you take ULORIC.


    In case of drug overdose, contact a healthcare practitioner (e.g. doctor), hospital emergency department or the regional Poison Control Centre, immediately even if there are no symptoms.

    Missed dose:

    If you miss a dose of ULORIC, take your ULORIC as soon as you remember. If it is almost time for the next dose, skip the missed dose and go back to the regular dosing schedule.

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    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.