Order Canadian Pharmacy Crestor Medication (Rosuvastatin)
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What is Crestor: An Overview
Crestor (Rosuvastatin) is given to patients to help lower the risk of heart attack and stroke by lowering cholesterol and additional fats in the blood.
This drug is classified as a HMG-CoA reductase inhibitor, commonly referred to as "statins".
The enzyme HMG-CoA reductase plays a key role in how cholesterol levels are balanced in the body. It is also referred by the generic name, rosuvastatin, which together with diet and exercise is prescribed to regulate the the cholesterol made within the body.
When there is excess cholesterol in the body, it can be a risk factor for cardiovascular disease. However, not all types of cholesterol are bad for the body. There are two types of cholesterol: LDL cholesterol and HDL cholesterol.
HDL cholesterol is coined the term "good" cholesterol as it removes the "bad" cholesterol known as LDL away from the body. When LDL cholesterol levels are elevated, it can lead to a buildup of plaque in the blood vessels, which can cause the blood vessels to narrow. This narrowing of arteries causes blood flow to be disrupted which can cause a stroke or lead to a heart attack.
This is a commonly prescribed medication to help control cholesterol levels to help prevent cardiovascular problems and strokes.
Learn About Crestor: Dosage, Effects, Interactions, and More
The active medicinal ingredient is Rosuvastatin calcium, which is manufactured by AstraZeneca. It is available in both and brand and generic options in the following dosage forms: 5mg, 10mg, 20mg, and 40mg. Generic Rosuvastatin from Canada comes in a pack size of 100 tablets in a bottle while the brand option can be in blister of 28 or 30 tablets.
Click on the blue boxes below for helpful information on how to take this medication and common side effects. Plus, read Crestor reviews toward the bottom for more information and experiences from our customers.
Crestor (Rosuvastatin) Medication Information
Crestor is a type of medication called an HMG Co-A reductase inhibitor, sometimes called “statins.”
Statins lower certain types of cholesterol associated with cardiovascular disease, including total cholesterol, LDL, and triglycerides. Statins also increase levels of “good” cholesterol called HDL.
The changes that statins make to cholesterol slow the buildup of atherosclerosis, which is “plaque” that forms inside blood vessels with small tears.
The long-term benefit of statins is that they lower the risk of heart attack and stroke.
Crestor is dosed between 5-40 mg per daily, depending on the intensity needed. The dosages are:
- Moderate intensity: 5-10 mg by mouth once daily
- High intensity: 20-40 mg by mouth once daily
The maximum dose is 40 mg once daily. Crestor can be taken with or without food.
Common side effects of Crestor may include:
- Abdominal pain
Crestor and other statin medication may cause increases in liver enzymes, also called transaminitis. Your doctor should monitor for changes to these enzymes before taking Crestor and while you are taking it.
Stop taking Crestor and tell your doctor if you experience unexplained muscle pain, tenderness, or weakness with dark-colored urine. This may be a sign of a rare but severe side effect called rhabdomyolysis. People at greater risk of this side effect include people taking certain medications, those with low thyroid, those over 65, and those with poor kidney function.
Talk with your doctor or pharmacist about any new medications you start taking. Common interactions with Crestor include:
- Red yeast rice
Store Crestor close to room temperature, 20-25ºC (68-77ºF) protected from moisture. Do not store it in the bathroom or kitchen.
- You can’t tell if Crestor is working, but you should still take it every day. Your doctor will do lab tests a few months after starting it to make sure the drug is working.
- A rare but severe side effect of Crestor is rhabdomyolysis. Immediately stop taking Crestor if you experience muscle pain and dark-colored urine.
- Crestor may take several weeks to months to start showing an effect.
Does Crestor have to be taken at night?
Some statins need to be taken at night because this is when cholesterol is produced. Crestor does not have to be taken at night and can be taken at any time because it stays in the body for longer than other statins.
How long do I have to take Crestor?
Crestor and other statin medications are taken lifelong.
Can I take Crestor if I have liver disease?
It depends on several factors, and your doctor should decide if it is safe for you to take with liver disease.
- Crestor [package insert]. Wilmington, DE: AstraZeneca; 2016.
Author: Dr. Conor Sheehy, PharmD, BCPS
Dr. Sheehy is a board-certified pharmacotherapy specialist. He has worked in multiple practice settings, including retail and hospital pharmacies, and in medical clinics. He specializes in anticoagulation, psychiatric medications, and diabetes medications. He strives to empower his patients to understand their medications and improve their overall medical care.
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.