Zetia (Ezetimibe) Dosage and Side Effects
ZETIA is a drug that lowers LDL cholesterol levels by reducing cholesterol absorption in the small intestine. LDL ("bad") cholesterol builds up in the walls of arteries and forms plaque, which narrows arteries and can lead to heart disease. High LDL cholesterol levels are a major cause of heart attacks and stroke. ZETIA is often prescribed along with a low-fat diet. It may be used by itself or in conjunction with a statin to reduce cholesterol. ZETIA may increase LDL-cholesterol uptake into cells and decrease levels of LDL in blood plasma.
Proper Use of this medication
ZETIA is available in 10-milligram tablets, and the usual dose is one tablet daily. The medication can be taken with or without a meal.
An overdose of ZETIA should not produce life-threatening symptoms, but seek emergency medical help if you think you have overdosed.
What Happens If I Missed Dose of Zetia:
If you miss a dose, take it as soon as you remember. Skip the dose if it is almost time for your next dose. Do not take extra medicine to make up for a missed dose. Do not take more than one dose of ZETIA a day.
Less serious side effects of ZETIA include:
- Numbness and tingling
- Stomach ache, diarrhea
- Depressed moods
- Cold symptoms
- Allergic reaction, hives, difficulty breathing
More serious side effects of ZETIA may demand immediate emergency medical attention and include:
- Chest pain
- Fever, sore throat, blistering skin rash
- Muscle weakness, pain
- Nausea, dark urine
- Severe dizziness, trouble breathing
Warnings and Precautions
Your doctor needs to know about any allergies you have, and about all the medications you take, whether prescription or over-the-counter, vitamins, illegal or recreational drugs, and dietary or herbal supplements, as they can affect how ZETIA works, and vice-versa.
It's also important to tell your health-care provider whether you have liver problems or thyroid disorder; are using steroids or hormones; or experience unwanted muscle pains or weakness.
Tell your doctor if you are pregnant or plan to become pregnant or are breastfeeding.
Rarely, ZETIA can cause a breakdown in skeletal muscle tissue, which can lead to kidney failure.
Interactions with this medication
ZETIA should not be taken at the same time as some cholesterol medicines. Wait four hours before taking:
- Cholestyramine (Questran)
- Colestipol (Colestid)
- Colesevelam (Welchol)
Care should be taken when combining warfarin (Coumadin) and ZETIA . It may increase your risk of bleeding.
Gemfibrozil (Lopid) or cyclosporine (Neoral) can increase blood levels of ZETIA , so watch for side effects if taken together.
ZETIA may be taken at the same time as statin drugs. It may take up to two weeks before cholesterol levels improve.
Because ZETIA is designed to lower your cholesterol, it works best with a low-fat, low-cholesterol diet.
Other related products
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.