Atacand (Candesartan)

(℞) Prescription Required- Atacand is also marketed as Amias

    Atacand (Candesartan) Dosage and Side Effects

    ATACAND is used to treat high blood pressure in children age 6 to 17 years and adults.  It is also used to treat heart failure in adults.

    Proper Use of this medication

    The dosage of ATACAND is individualized.

    Take ATACAND exactly as prescribed. It is recommended to take your dose at about the same time everyday.

    ATACAND is taken once a day. Even if your doctor has prescribed 2 tablets a day, both should be taken at the same time, unless otherwise indicated.

    ATACAND may be taken with food or on an empty stomach but it should be taken consistently the same way each day.

    Swallow ATACAND with a glass of water.

    How to use the blister packs:

    • As an aid to help you keep track of your doses, ATACAND comes in a blister pack. The days of the week are printed on the back of the blister. To start, take the tablet that matches the day of the week. Continue taking the tablets in order, until they are all finished.

    • There are 14 days of labeled tablets in each blister, with one extra to make 15. All 15 tablets, including the one labeled “Take this tablet last”, are exactly the same. Once you have finished the 14 labeled tablets, take the one marked “Take this tablet last” before starting your next blister pack.

    Usual dose:

    Lower doses may be required based on the other medications you take and the presence of other disease conditions.

    High Blood Pressure in Adults:

    Recommended Initial Dose: 16 mg once a day.

    Total Daily Dose: 8 mg to 32 mg once a day.

    High Blood Pressure in Children (6 to 17 years of age):

    • For children who weigh less than 50 kg:

      Recommended Starting Dose: 4 mg once a day.

      Maximum Dose: 8 mg once a day.

    • For children who weigh 50 kg or more:

      Recommended Starting Dose: 8 mg once a day.

      Maximum Dose: 16 mg once a day.

    ATACAND must not be given to children under 1 year of age due to the potential risk to the developing kidneys.

    Heart Failure in Adults:

    Usual Recommended Initial Dose: 4 mg once a day. If tolerated by the patient, this dose is gradually doubled (approximately every 2 weeks) until the target dose is reached.

    Target Dose: 32 mg once a day.

    Missed dose:

    If you miss a dose of ATACAND and remember within 12 hours, you should take your usual dose as soon as possible. Then go back to your regular schedule. But if it is more than 12 hours when you remember, do not take the missed dose. Just take the next dose on time.

    Never take a double dose of ATACAND to make up for missed tablets. If you are still unsure, check with your doctor or pharmacist to see what you should do.

    Side Effects

    Side effects may include:

    • dizziness, falls

    • drowsiness, insomnia

    • rash

    • diarrhea, vomiting

    • headache

    • back or leg pain, muscle cramps

    • cough

    • sore throat

    • dry mouth

    • cold symptoms

    • pneumonia

    • fainting spells

    • confusion

    Side effects in adults and children are similar, but may occur more often in children.

    If any of these affects you severely, tell your doctor, nurse or pharmacist.

    ATACAND can cause abnormal blood test results. Your doctor will decide when to perform blood tests and will interpret the results.

    Warnings and Precautions

    Before you use ATACAND talk to your doctor, nurse or pharmacist if you:

    • Have experienced an allergic reaction to any drug used to lower blood pressure, including angiotensin converting enzyme (ACE) inhibitors.

    • Have narrowing of an artery or a heart valve.

    • Have had a heart attack or stroke.

    • Have heart failure.

    • Have diabetes, heart, liver or kidney disease.

    • Are on dialysis.

    • Are dehydrated or suffer from excessive vomiting, diarrhea, or sweating.

    • Are taking a salt substitute that contains potassium, potassium supplements, or a potassium-sparing diuretic (a specific kind of “water pill” that makes your body keep potassium) or other drugs that may increase potassium levels (e.g., heparin, co-trimoxazole).

    • Are on a low-salt diet.

    • Are taking a medicine that contains aliskiren, such as Rasilez, used to lower high blood pressure. The combination with ATACAND is not recommended.

    • Are taking an angiotensin converting enzyme (ACE) inhibitor. You can recognize ACE inhibitors because their medicinal ingredient ends in “-PRIL”.

    • Are taking an ACE-inhibitor together with a medicine which belongs to the class of medicines known as mineralocorticoid receptor antagonists (for example, spironolactone, eplerenone). These medicines are for the treatment of heart failure.

    Driving and using machines:

    Before you perform tasks which may require special attention, wait until you know how you respond to ATACAND. Dizziness, lightheadedness, or fainting can especially occur after the first dose and when the dose is increased.

    If you are currently taking ATACAND and are going to have an operation, be sure to tell your doctor or dentist about your medication before you are given an anaesthetic.

    Interactions with this medication

    As with most medicines, interactions with other drugs are possible. Tell your doctor, nurse, or pharmacist about all the medicines you take, including drugs prescribed by other doctors, vitamins, minerals, natural supplements, or alternative medicines.

    The following may interact with ATACAND:

    • Agents increasing serum potassium, such as a salt substitute that contains potassium, potassium supplements, potassium-sparing diuretic (a specific kind of “water pill”, or other drugs that may increase potassium levels (e.g., heparin, co-trimoxazole).

    • Lithium used to treat bipolar disease.

    • Nonsteroidal anti-inflammatory drugs (NSAIDs), used to reduce pain and swelling. Examples include ibuprofen, naproxen, and celecoxib.

    • Blood pressure-lowering drugs, including diuretics (“water pills”), aliskiren-containing products (e.g. Rasilez) or angiotensin converting enzyme (ACE) inhibitors.

    • Mineralocorticoid receptor antagonists (for example, spironolactone, eplerenone) and ACE inhibitors used in Heart failure.

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    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.