Cozaar (Losartan)

(℞) Prescription Required

    Cozaar (Losartan) Dosage and Side Effects

    COZAAR is used to lower blood pressure by relaxing the blood vessels.

    Warnings and Precautions

    BEFORE you use COZAAR talk to your physician or pharmacist if:

    • you perform tasks which may require special attention (for example, driving an automobile or operating dangerous machinery). Almost all patients can, but you should not perform these tasks until you know how you respond to your medicine.

    • you have or have had any medical problems, and about any allergies.

    • you are taking potassium supplements, potassium-sparing agents or salts substitutes containing potassium.

    • you are taking a medicine that contains aliskiren, such as Rasilez, used to lower high blood pressure. The combination with COZAAR is not recommended.

    • you are taking an angiotensin-converting-enzyme inhibitor (ACEI).

    • you are taking any medication including non-prescription and herbal products.

    • you have recently suffered from excess vomiting or diarrhea.

    • you have liver, kidney, heart or heart valve disease.

    • you are allergic to this drug or to any ingredient in the formulation.

    You are pregnant, breast-feeding or thinking of becoming pregnant?

    Taking COZAAR during pregnancy can cause injury and even death to your baby. This medicine should not be used during pregnancy. If you are planning to become pregnant while taking COZAAR, contact immediately your physician.

    It is possible that COZAAR passes into breast milk. You should discuss with your physician about taking COZAAR while breast-feeding.

    Remember that your physician has prescribed this medicine only for you. Never give it to anyone else.

    Side Effects

    Any medicine may have unintended or undesirable effects, so-called side effects. Some patients may experience fatigue, hives, taste alteration or vomiting. Tell your physician or pharmacist promptly about these or any other unusual symptoms.

    Some patients, especially those with type 2 diabetes with protein in the urine, may also develop increased levels of potassium in their blood.

    Interactions with this medication

    As with most medicines, interaction with other drugs is possible. Therefore, do not take any other medicines unless you have discussed the matter with your physician or your pharmacist. It is important to tell your physician if you are taking:

    • Lithium salts

    • Digitalis

    • Warfarin

    • Rifampin

    • Erythromycin

    • Fluconazole

    • Phenobarbital

    • Cimetidine

    • Non-steroidal anti-inflammatory drugs (such as indomethacin)

    • Diuretics (water pills)—patients on diuretics may occasionally experience an excessive reduction of blood pressure after initiation of therapy with COZAAR

    • Potassium supplements or salt substitutes containing potassium

    • Other blood pressure medicines

    Certain medicines tend to increase your blood pressure, for example, some, but not all, non-prescription preparations for appetite control, asthma, colds, coughs, hay fever and sinus problems.

    Proper Use of this medication

    Usual dose:

    • Take COZAAR every day exactly as your physician has instructed. It is important to continue taking COZAAR for as long as your physician prescribes it in order to maintain smooth control of your blood pressure.

    • COZAAR may be taken with or without food, but it should be taken consistently with respect to food intake, at about the same time every day.


    • For adult patients, the usual starting dose is 50 mg once daily. The usual dose range is 50 to 100 mg once daily.

    • Most older patients require the same dose as younger patients, since COZAAR works equally well and is equally well tolerated by most older and younger adult patients.

    • For pediatric patients (6-16 years of age) who can swallow tablets, the recommended dose is 25 mg once daily in patients between 20 and 49 kg. The dose can be increased to a maximum of 50 mg once daily. In patients greater or equal to 50 kg, the starting dose is 50 mg once daily. The dose can be increased to a maximum of 100 mg once daily.

    Type 2 diabetes patients with proteinuria and hypertension:

    • For adults, the usual starting dose is 50 mg once daily. The dose may be increased to 100 mg once daily.


    In case of an overdose, contact a physician, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.

    Missed dose:

    Try to take COZAAR daily as prescribed. However, if you miss a dose, do not take an extra dose. Just resume your usual schedule.

    Other related products

    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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