Trelegy Ellipta (Fluticasone/Umeclidinium/Vilanterol)
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Trelegy Ellipta (Flucticasone/Umeclidinium/Vilanterol) Dosage and Side Effects
TRELEGY ELLIPTA is a combination of an inhaled corticosteroid (ICS), a long-acting muscarinic antagonist (LAMA), and a long-acting beta2-adrenergic agonist (LABA), delivered once-daily in GSK’s Ellipta dry powder inhaler.
Trelegy Ellipta is used to improve symptoms and prevent bronchospasm in adults with COPD (chronic obstructive pulmonary disease), including bronchitis and emphysema.
Proper Use of this medication
Use Trelegy Ellipta exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Using Trelegy Ellipta improperly can cause death or serious side effects on the heart.
Trelegy Ellipta is a powder that comes with a special inhaler device preloaded with blister packs containing measured doses of the medicine. The device opens and loads a blister of the medicine each time you use the inhaler. Follow the patient instructions provided with the inhaler device.
You may need to stop using other COPD medications you have been using in the past on a regular basis. Carefully follow your doctor's dosing instructions.
Trelegy Ellipta will not work fast enough to treat a bronchospasm attack. Use only a fast-acting inhalation medicine for an attack. Tell your doctor if any of your medicines seem to stop working as well in controlling your COPD.
The usual dose of Trelegy Ellipta is 1 inhalation per day. Use the medicine at the same time each day, and not more than once in a 24-hour period.
Seek medical attention if your breathing problems do not improve, or if your symptoms get worse quickly.
To reduce the chance of developing a yeast infection in your mouth, rinse with water (but do not swallow) after using this medicine.
While using Trelegy Ellipta, you may need frequent blood tests. Your vision and your bone mineral density may also need to be checked.
Store at room temperature away from moisture, heat, and light. Keep the inhaler device in the sealed foil tray until ready to start using it.
Throw the Trelegy Ellipta inhaler device away 6 weeks after you have taken it out of the foil pouch, or if the dose indicator shows a zero, whichever comes first.
Get emergency medical help if you have signs of an allergic reaction to Trelegy Ellipta: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
chest pain, fast or pounding heartbeats, pounding in your neck or ears;
anxiety, tremors, nervousness;
wheezing, choking, or other breathing problems after using this medication;
painful or difficult urination;
feeling very weak or tired, vomiting, and feeling like you might pass out;
sores or white patches in your mouth and throat, pain when swallowing;
fever, chills, cough with yellow or green mucus; or
blurred vision, tunnel vision, eye pain, or seeing halos around lights.
Common Trelegy Ellipta side effects may include:
pain in you mouth or throat;
nausea, vomiting, diarrhea;
headache, back pain; or
changes in your sense of taste.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Interactions with this medication
Tell your doctor about all your current medicines and any you start or stop using, especially:
antifungal or antiviral medicine;
cold or allergy medicine that contains an antihistamine (Benadryl and others);
medicine to treat Parkinson's disease;
medicine to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome;
bladder or urinary medicines - darifenacin, fesoterodine, oxybutynin, tolterodine, solifenacin; or
bronchodilators - aclidinium, ipratropium, tiotropium, umeclidinium.
Other drugs may interact with fluticasone, umeclidinium, and vilanterol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Warnings and Precautions
Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chickenpox or measles. These conditions can be serious or even fatal in people who are using medicine that contains a steroid.
Do not use a second inhaled bronchodilator similar to vilanterol, such as salmeterol (Advair, Serevent), indacaterol (Arcapta), formoterol or arformoterol (Foradil, Perforomist, Symbicort, Brovana).
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.