Trandate (Labetalol Hydrochloride)

(℞) Prescription Required

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Trandate 100mg

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Manufactured by: RPH Pharmaceuticals
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Trandate 100mg
Product of United Kingdom
Manufactured by RPH Pharmaceuticals
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Labetalol 200mg

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Manufactured by: UK Various Generics
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Labetalol 200mg
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Labetalol 400mg

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Labetalol 400mg
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Labetalol HCl 200mg

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Manufactured by: Mylan
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Labetalol HCl 200mg
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Manufactured by Mylan
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Trandate 100mg

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Manufactured by: Shire
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Trandate 100mg
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Trandate 200mg

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Manufactured by: Paladin Labs Inc.
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Trandate 200mg
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Trandate (labetalol) Dosage and Side Effects

TRANDATE is a drug used to treat high blood pressure. This medicine is in a group of drugs called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.

Warnings and Precautions

You should not stop taking TRANDATE without talking to your doctor first. If this drug is stopped suddenly, it may cause chest pain or heart attack in some people.

This medication may also make you drowsy, so you should not drive a car or operate machinery until you know how it will affect you.

Your blood pressure should be checked regularly to evaluate your response to TRANDATE. You should also check your pulse periodically. If your pulse rate is faster or slower than it should be, call your doctor.

Before taking TRANDATE, you should tell your doctor and pharmacist if you:

  • Are allergic to it or another other drugs
  • Have ever had heart, kidney, or liver disease; asthma or other lung disease; severe allergies; diabetes, or pheochromocytoma (an adrenal gland tumor)
  • Are pregnant, plan to become pregnant, or are breastfeeding
  • Are having surgery, including dental surgery

TRANDATE and Pregnancy

It's not known whether TRANDATE will harm an unborn baby, though the drug has been linked to heart and lung problems in newborns.

TRANDATE can pass into breast milk and may harm a breastfeeding baby.

Side Effects

Common Side Effects of TRANDATE

Some side effects of TRANDATE may include:

  • Excessive tiredness
  • Tingling scalp or skin
  • Dizziness
  • Lightheadedness
  • Upset stomach
  • Stuffy nose
  • Fatigue

Serious Side Effects of TRANDATE

If you experience any of the following symptoms, call your doctor immediately:

  • Swelling of the lower legs and feet
  • Sudden weight change
  • Shortness of breath or wheezing
  • Chest pain
  • Severe slow heart rate

Interactions with this medication

Patients who take diabetes medications to lower blood sugar (such as insulin or oral antidiabetic drugs) may need to monitor their blood sugar more frequently while taking TRANDATE.

Halothane anesthesia may contribute to the blood-pressure lowering effects of TRANDATE.

Combining TRANDATE with tricyclic antidepressants such as amitriptyline (Elavil, Endep), imipramine (Tofranil), or nortriptyline (Pamelor) may lead to an increase in tremor.

If combined with adrenergic-stimulating drugs used for treating asthma, such as albuterol (Proventil, Ventolin) or pirbuterol (Maxair), the effects of TRANDATE may counteract the effects of the stimulating drugs and reduce their effectiveness.

Cimetidine (Tagamet) may increase the effectiveness of TRANDATE by blocking its elimination and increasing its levels in the blood. Less TRANDATE may be needed when cimetidine and TRANDATE are used together.

You should tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs or supplements you are taking.

You can continue your normal diet and activities unless otherwise instructed by your doctor while taking TRANDATE. However, consuming alcohol while on TRANDATE can make you drowsier.

Proper Use of this medication

The recommended starting oral dose of TRANDATE is 100 milligrams (mg), twice a day.

The dose can be increased by 100 mg twice daily, every two to three days based on your response.

Usual maintenance doses are 200-400 mg, twice daily. People with very high blood pressure may require 1.2 to 2.4 grams daily.

The initial intravenous dose of the drug is 20 mg injected over two minutes.

Additional injections of 40 or 80 mg may be given every 10 minutes as needed up to a total dose of 300 mg.

The medicine may also be given by intravenous infusion at 1 to 2 milligrams/minute.

TRANDATE Overdose

If you suspect an overdose, you should contact a poison control center or emergency room immediately.

Missed Dose of TRANDATE

If you miss a dose of TRANDATE, take it as soon as you remember.

However, if it is almost time for the next dose, skip the missed dose and continue to follow your regular dosing schedule.

Do not double up on doses.

Other related products

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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