Trandate (Labetalol Hydrochloride)
Trandate (labetalol) Dosage and Side Effects
TRANDATE is a drug used to treat high blood pressure. This medicine is in a group of drugs called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure.
Warnings and Precautions
You should not stop taking TRANDATE without talking to your doctor first. If this drug is stopped suddenly, it may cause chest pain or heart attack in some people.
This medication may also make you drowsy, so you should not drive a car or operate machinery until you know how it will affect you.
Your blood pressure should be checked regularly to evaluate your response to TRANDATE. You should also check your pulse periodically. If your pulse rate is faster or slower than it should be, call your doctor.
Before taking TRANDATE, you should tell your doctor and pharmacist if you:
- Are allergic to it or another other drugs
- Have ever had heart, kidney, or liver disease; asthma or other lung disease; severe allergies; diabetes, or pheochromocytoma (an adrenal gland tumor)
- Are pregnant, plan to become pregnant, or are breastfeeding
- Are having surgery, including dental surgery
TRANDATE and Pregnancy
It's not known whether TRANDATE will harm an unborn baby, though the drug has been linked to heart and lung problems in newborns.
TRANDATE can pass into breast milk and may harm a breastfeeding baby.
Common Side Effects of TRANDATE
Some side effects of TRANDATE may include:
- Excessive tiredness
- Tingling scalp or skin
- Upset stomach
- Stuffy nose
Serious Side Effects of TRANDATE
If you experience any of the following symptoms, call your doctor immediately:
- Swelling of the lower legs and feet
- Sudden weight change
- Shortness of breath or wheezing
- Chest pain
- Severe slow heart rate
Interactions with this medication
Patients who take diabetes medications to lower blood sugar (such as insulin or oral antidiabetic drugs) may need to monitor their blood sugar more frequently while taking TRANDATE.
Proper Use of this medication
The recommended starting oral dose of TRANDATE is 100 milligrams (mg), twice a day.
The dose can be increased by 100 mg twice daily, every two to three days based on your response.
Usual maintenance doses are 200-400 mg, twice daily. People with very high blood pressure may require 1.2 to 2.4 grams daily.
The initial intravenous dose of the drug is 20 mg injected over two minutes.
Additional injections of 40 or 80 mg may be given every 10 minutes as needed up to a total dose of 300 mg.
The medicine may also be given by intravenous infusion at 1 to 2 milligrams/minute.
If you suspect an overdose, you should contact a poison control center or emergency room immediately.
Missed Dose of TRANDATE
If you miss a dose of TRANDATE, take it as soon as you remember.
However, if it is almost time for the next dose, skip the missed dose and continue to follow your regular dosing schedule.
Do not double up on doses.
Other related products
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.