Trandate (Labetalol Hydrochloride)

Trandate (Labetalol) Medication Information

Uses

Trandate is a beta blocker that is used to treat high blood pressure.

Dosage

The tablets are available in several different strengths:

• 100 mg
• 200 mg
• 300 mg

Side Effects

The most common side effects of Trandate include:

• Fatigue 
• Headache
• Nausea
• Vomiting
• Dizziness
• Impotence
• Edema
• Bradycardia 

Speak with your doctor for a full list of side effects that apply to you if you are taking Labetalol.

Precautions

Trandate is metabolized in the liver, so it should be used with caution in patients with liver dysfunction. 

Trandate can cause intraoperative floppy iris syndrome during cataract surgery. 

Interactions

Some common drug interactions with Trandate include:

• TCAs 
• Inhaled beta-agonists
• Cimetidine
• Nitroglycerine
• Verapamil
• Digoxin 

Speak with your doctor for more information and before starting a new medication with Labetalol. 

Storage

Store at room temperature (59-86 ºF). It is important to it from excessive moisture. 

Pharmacist Tips

• Trandate dose can be titrated to best meet the need of each patient.
• Trandate is typically doses twice a day.
• Trandate can be used with or without a diuretic to control blood pressure.

Labetalol FAQs

Does Trandate work immediately?

It can take a few days to see the effect of Trandate. 

How much can Trandate lower your blood pressure?

On average Labetalol can lower systolic blood pressure by 10 mmHg. 

What happens if you take Trandate without food?

The amount of Labetalol that the body can absorb is increased with food.  

How many hours apart should I take Trandate?

It is best to try and space the doses 12 hours apart as much as possible. 

Can I have a glass of wine on Trandate?

Alcohol can increase the dizziness and blood pressure lowering of Trandate, so it is not recommended that you drink while taking Trandate. 

Related Drugs

• Prinivil
• Norvasc
• Zestril

Reference:

Trandate {package insert}. San Diego, CA: Prometheus Laboratories Inc.; 2010.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/018716s026lbl.pdf