Rexulti (Brexpiprazole)

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    Rexulti (Brexpiprazole) Dosage and Side Effects

    BREXPIPRAZOLE (brex PIP ray zole) is an antipsychotic. It is used to treat schizophrenia. This medicine is also used in combination with antidepressants to treat major depressive disorder.

    This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

    Proper Use of this medication

    Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take this medicine with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional. A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

    Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

    Side Effects

    Side effects that you should report to your doctor or health care professional as soon as possible: -allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue -breathing problems -confusion -feeling faint or lightheaded, falls -fever or chills, sore throat -increased hunger or thirst -increased urination -problems with balance, talking, walking -restlessness or need to keep moving -seizures -suicidal thoughts or other mood changes -trouble swallowing -uncontrollable head, mouth, neck, arm, or leg movements -unusually weak or tired Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): -constipation -drowsiness -headache -stomach upset -weight gain

    This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Interactions with this medication

    Do not take this medicine with any of the following medications: -aripiprazole -metoclopramide This medicine may also interact with the following medications: -clarithromycin -certain medicines for blood pressure -certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole -duloxetine -fluoxetine -paroxetine -quinidine -rifampin -St. John's Wort

    This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

    Warnings and Precautions

    Visit your doctor or health care professional for regular checks on your progress. It may be several weeks before you see the full effects of this medicine. Notify your doctor or health care professional if your symptoms get worse, if you have new symptoms, if you are having an unusual effect from this medicine, or if you feel out of control, very discouraged or think you might harm yourself or others. Do not suddenly stop taking this medicine. You may need to gradually reduce the dose. Ask your doctor or health care professional for advice. You may get dizzy or drowsy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase dizziness and drowsiness. Avoid alcoholic drinks. This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe. This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.

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    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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