Lidex Gel (Fluocinonide)

(℞) Prescription Required

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Lyderm Gel 0.05%

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Manufactured by: Taro Pharmaceuticals Ltd.
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Lyderm Gel 0.05%
Product of Canada
Manufactured by Taro Pharmaceuticals Ltd.
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Lidex Gel (Fluocinonide) Medication Information


Lidex is a topical corticosteroid that is used to treat atopic dermatitis, psoriasis, and other inflammatory skin conditions. 


The gel is available in 0.05% concentration.

Side Effects

The most common side effects of Lidex include:

  • Localized burning
  • Acne
  • Allergic dermatitis
  • Pruritus
  • Hyperglycemia
  • Growth suppression
  • Secondary infection
  • Irritation 

Speak with your doctor for a full list of side effects that apply to you if you are taking Lidex.


With all corticosteroids, there is a risk of adrenal suppression. Patients who receive high doses for a long period of time are at the most risk. 

Skin reactions can occur with this medication, monitor for any irritation or rash and alert your doctor if you notice any changes. 

There is a risk of Kaposi sarcoma with prolonged steroid treatment. If Kaposi develops the steroid should be stopped. 


Aldesleukin can be affected by Lidex co-administration. This is the only reported drug interaction with Lidex.  

Speak with your doctor for more information and before starting a new medication with Lidex. 


Store at room temperature (59-86ºF). 

Pharmacist Tips

  • Lidex therapy should be limited to 2 weeks. 
  • Lidex should be applied once or twice a day to the affected area. 
  • When applying Lidex, use a sparingly thin layer. Be sure to wash your hands following application of Lidex.  

Fluocinonide FAQs

How long does Lidex take to work?

You should see full resolution of your skin condition within 2 weeks of therapy.


Is Fluocinonide a strong steroid?

Fluocinonide is a prescription strength steroid. 


Is Lidex a steroid?

Yes, Lidex is a topical steroid. 


Is Fluocinonide the same as Lidex?

Yes, fluocinonide is the generic name for Lidex. 


How long should you use Lidex?

Lidex should not be used for longer than 2 weeks. 


Related Drugs


Lidex {package insert}. Scottsdale, AZ: Patheon, Inc.; 2006.

PharmD Medical Writer

Author: Dr. Larisa Roybal, PharmD

Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.

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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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