Amaryl (Glimepiride)

(℞) Prescription Required

    Amaryl (Glimepiride) Dosage and Side Effects

    AMARYL is used to treat patients with type 2 diabetes.

    Proper Use of this medication

    You should take AMARYL as directed by your doctor.

    Typically, you will take the medication by mouth with breakfast or with the first meal of the day, usually once daily.

    Your dose will be based on your medical condition and response to treatment.

    The recommended starting dose of AMARYL is 1 or 2 milligrams (mg), once a day with breakfast or first main meal.

    If you are at increased risk for hypoglycemia (elderly patients or those with kidney impairment), you should start on 1 mg, once daily.

    After reaching a daily dose of 2 mg, further dose increases can be made. The maximum recommended dose is 8 mg, once daily.

    AMARYL Overdose

    If you suspect an overdose, you should contact a poison control center or emergency room immediately.

    You can get in touch with a poison control center at (800) 222-1222.

    Missed Dose of AMARYL

    If you miss a dose of AMARYL, take it as soon as you remember.

    If it's almost time for the next dose, skip the missed dose and continue on your regular schedule.

    Do not double up on doses to make up for a missed dose.

    Side Effects

    Common Side Effects of AMARYL

    AMARYL may cause changes in your blood sugar, which could cause blood sugar levels to fluctuate.

    Symptoms of low blood sugar include:

    • Sudden sweating
    • Shaking
    • Fast heartbeat
    • Hunger
    • Blurred vision
    • Dizziness
    • Tingling in the hands or feet

    You may want to carry glucose tablets or gels with you to treat low blood sugar episodes.

    Serious Side Effects of AMARYL

    Some side effects of AMARYL can be serious. You should call your doctor immediately if you experience:

    • Yellowing of the skin or eyes (jaundice)
    • Dark urine
    • Light-colored stools
    • Pain in the upper right part of the stomach
    • Diarrhea
    • Fever
    • Sore throat
    • Unusual bruising or bleeding

    Warnings and Precautions

    AMARYL helps control blood sugar, but it will not cure your diabetes. You should continue to take AMARYL even if you feel well.

    This medication should not be used to treat patients with type 1 diabetes, a disease in which the body does not produce insulin. AMARYL will only help lower blood sugar if your body produces insulin naturally.

    In one study, patients who took a medication similar to AMARYL to treat diabetes were more likely to die of heart problems than those who were treated with diet changes and insulin.

    Talk to your doctor about the risks of this treatment.

    While taking AMARYL, you should tell your doctor if you:

    • Are pregnant, plan to become pregnant, or are breastfeeding
    • Are having surgery, including dental surgery
    • Have ever had G6PD deficiency (a genetic blood disorder)
    • Have hormone disorders involving the adrenal, pituitary, or thyroid gland
    • Have heart, kidney, or liver disease

    Interactions with this medication

    Many drugs can affect your blood sugar levels and make them more difficult to control.

    You should talk with your doctor or pharmacist before you start, stop, or change any medication.

    If you are taking another anti-diabetic drug such as chlorpropamide (Diabinese), follow your doctor's instructions carefully for stopping the old drug and starting on AMARYL.

    The drug colesevelam (Welchol) can decrease the absorption of AMARYL. You will need to take AMARYL at least four hours before taking colesevelam.

    You should tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs or supplements you are taking.

    AMARYL and Alcohol

    Alcohol can worsen the side effects of AMARYL and may cause symptoms such as flushing, headache, chest pain, nausea, vomiting, weakness, blurred vision, mental confusion, sweating, choking, difficulty breathing, and anxiety.

    Limit or avoid drinking alcohol while taking AMARYL.

    You should also avoid unnecessary exposure to the sun while taking AMARYL because the drug can make your skin more sensitive to sunlight.

    Other related products

    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.