Zocor (Simvastatin)

Zocor (Simvastatin) Medication Information

Uses

Zocor is a HMG-CoA reductase inhibitor, also referred to commonly as a statin, and it is used to treat hyperlipidemia. 

Dosage

The tablets are available in several different strengths:

• 5 mg
• 10 mg
• 20 mg
• 40 mg
• 80 mg

Side Effects

The most common side effects of Zocor include:

• Abdominal pain
• Constipation
• Nausea
• Headache
• Respiratory tract infection 

Speak with your doctor for a full list of side effects that apply to you if you are taking Zocor.

Precautions

There is a risk of myopathy when taking Zocor, patients should monitor for unexplained muscle pain and discuss with their doctor if they have any.

There is a possibility of seeing an increase in liver enzymes while taking Zocor, so patients should be monitored for liver function. 

Interactions

A common drug interaction with Zocor includes:

• Itraconazole
• Clarithromycin
• Nefazodone
• Gemfibrozil
• Cyclosporine
• Amiodarone
• Verapamil
• Grapefruit juice

Speak with your doctor for more information and before starting a new medication with Zocor. 

Storage

Store at room temperature (41-86 ºF). 

Pharmacist Tips

• If you are taking Zocor there is a risk of developing myopathy and you should monitor for muscle pain. 
• You should stick to a diet and exercise plan in addition to taking Zocor. 
• Your doctor will monitor your liver function while you are taking Zocor.

Simvastatin FAQs

How long does it take for Zocor to lower cholesterol?

It can take a few weeks to see the benefit of Zocor.

Can I just quit taking Zocor?

Zocor is an important medication for reducing your risk of having a heart attack or stroke, so you should not quit taking it without your doctors advice. 

What food should I avoid with Zocor?

You should avoid grapefruit while taking Zocor. 

What are the side effects of Zocor?

The most common side effects with Zocor are stomach pain, constipation, nausea, muscle pain, and headache. 

Does Zocor cause weight gain?

Weight gain is not a common side effect seen with Zocor. 

Related Drugs

• Crestor
• Lescol
• Lipitor
• Livalo
• Zetia

Reference:

Zocor {package insert}. Whitehouse Station, NJ: Merck & Co., Inc.; 2010.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/019766s078lbl.pdf