Restasis Eye Drops (Cyclosporin)

(℞) Prescription Required

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    Restasis Eye Drops (Cyclosporine) Dosage and Side Effects

    RESTASIS is used to treat certain patients whose eyes are not producing enough tears to keep the eye moist and comfortable.

    Proper Use of this medication

    Usual adult dose:

    The usual adult dose of RESTASIS is one drop into each affected eye. This dose should be applied twice a day—about 12 hours apart.

    Before using, gently shake the vial by tipping it up and down a few times until the emulsion is white and appears the same throughout the vial.

    Each individual, single-use vial should be used immediately after opening for administration to one or both eyes, and the remaining contents discarded immediately after administration.

    RESTASIS may be used together with artificial tears. Wait 15 minutes between using RESTASIS and the artificial tear product.


    If you have taken too much RESTASIS, particularly accidental oral ingestion, contact your healthcare practitioner (e.g. doctor), hospital emergency department or regional Poison Control Centre, even if there are no symptoms.

    Missed dose:

    If you miss a dose, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and go back to the regular dosing schedule. Do not double your dose.

    Side Effects

    Ocular burning is a very common (≥1/10) adverse event with RESTASIS. Other common events (≥1/100) are eye irritation, headache, foreign body sensation in eye, ocular/conjunctival hyperaemia (redness), eye pain, eye stinging, eye discharge, photophobia, eye pruritus, blurred vision, dry eye. These events usually get better on their own, as your eye becomes used to treatment with RESTASIS.

    There is the potential to experience an allergic reaction to RESTASIS. Reactions of face swelling, tongue swelling, throat swelling, shortness of breath and itchy skin rash have been reported with the use of RESTASIS. If an allergic reaction occurs, discontinue the drug and contact your physician.

    This is not a complete list of side effects. For any unexpected effects while taking RESTASIS, contact your doctor or pharmacist.

    Warnings and Precautions

    BEFORE you use RESTASIS, talk to your doctor or pharmacist if:

    You have a history of herpes keratitis. RESTASIS has not been tested for use in people with this condition.

    Your dry eyes are the result of Vitamin A deficiency or scarring. RESTASIS has not been studied in people with these causes of dry eyes.

    You drive or operate machinery. RESTASIS may cause your vision to blur right after you put the drops in. Wait a few minutes until your vision clears before you try to drive or operate a machine.

    You are breast feeding a baby. It is not known whether or not cyclosporine is passed into breast milk.

    You are pregnant or planning to become pregnant. While there are no known adverse effects on human pregnancy, there is very little information available, and you should decide with your doctor how best to proceed.

    Do not administer RESTASIS while you wear contact lenses. If you must wear contact lenses, remove the lenses before applying RESTASIS. Wait for 15 minutes before you put your contact lenses back in.

    You should also avoid touching the tip of the vial to the eye or any surface as this may contaminate the emulsion, or touching the eye may cause injury.

    Interactions with this medication

    No drug interaction studies have been performed with RESTASIS. Concomitant use with other eye products should be discussed with your doctor beforehand.

    Other related products

    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.