EpiPen (Epinephrine)
Medication information written by Dr. Larisa Roybal, PharmD
Updated - April 1, 2021
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Epipen (Epinephrine) Medication Information
Uses
Epipen is an auto injector used to emergently treat allergic reactions.
Dosage
The pen is available in 1:2000 strength.
Side Effects
The most common side effects of Epipen include:
- Moderate anxiety
- Restlessness
- Tremor
- Dizziness
- Sweating
- Nausea
- Vomiting
- Headache
Speak with your doctor for a full list of side effects that apply to you if you are taking Epipen.
Precautions
If patients use an Epipen, they should seek emergency care.
Epipens should be used cautiously in patients who have heart arrythmias.
Interactions
Common drug interactions with Epipen include:
- TCAs
- MAOIs
- Levothyroxine
- Antihistamine
- Chlorpheniramine
- Diphenhydramine
Speak with your doctor for more information and before starting a new medication with Epipen.
Storage
Do at room temperature (77 ºF). Protect from light.
Pharmacist Tips
- The Epipen will deliver 0.3 mg or epinephrine.
- The auto injector Epipen will dispense one dose of epinephrine.
- Patients should periodically inspect their Epipen for discoloration or particles.
Epinephrine FAQs
What should you do after using an Epipen?
After administering the Epipen, seek immediate medical attention.
Can you use Epipen through clothing?
You can administer Epipen through clothing if you need to.
How many times can you use an Epipen?
There is only one dose in an Epipen
How long do you hold the Epipen in place?
Hold the Epipen in place for 10 seconds.
Where do you inject the Epipen?
The Epipen should be injected on the outside of the thigh.
Related Drugs
Reference:
Epipen {package insert}. Columbia, MD: Meridian Medical Technologoes, Inc.; 2008.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/019430s044lbl.pdf
Author: Dr. Larisa Roybal, PharmD
Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.