Entresto (Sacubitril/Valsartan)

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    Entresto (Sacubitril/Valsartan) – Product Information

    Entresto is a prescription medication that is used to lessen the risk of cardiovascular death. People taking it are not highly likely to get hospitalized for Class II and Class IV heart failure.

    To buy Entresto online, connect with our PricePro Pharmacy team by the phone or our live online chat. You can also check out our reviews to see how we have helped over thousands of patients find safe and affordable medication.

    This medication is manufactured by Novartis, and we carry it in these dosages: 24mg/26mg, 49mg/51mg and 97mg/103mg. There are two active medicinal ingredients are sacubitril and valsartan. We offer this medication from both Canada and the United Kingdom. The shipping time would be 7 to 10 business days from when the dispensing pharmacy fills the order.  You can simply view our low Entresto price by clicking on the "Check Prices" dosage box above.

    What is Entresto used for?

    This is a medicine that contains two main ingredients: valsartan and sacubitril. Sacubitril is a medicine for blood pressure and its role is to increase the amount of specific proteins in the body that are able to dilate and relax the blood vessels. As the vessels dilate, the blood pressure is lowered. On the other hand, valsartan is an ARB (angiotensin II receptor blocker) that can stop your blood vessels from getting narrow.

    Due to this, the blood pressure is lowered while the blood flow increases. It is normally prescribed to those who have chronic heart failure. It is able to reduce their risk of ever requiring hospitalization when their symptoms worsen. Additionally,  it lowers the risk of death due to heart failure. Normally, this drug is prescribed along with other medicines for reducing blood pressure.


    To begin, ensure that you take this medicine just as your doctor prescribes it. Do not take a smaller or bigger dose. Additionally, don’t exceed the date when your doctor wants you to stop taking the medicine.  Usually, Entresto is taken with food or without food at the same hour every day. If your doctor alters your dose, take note of the changes and follow the new instructions to attain the best results.

    As for the right dosage to take, the first dose for those with congestive heart failure will normally be taken two times a day. It will consist of 49mg sacubitril and 51mg valsartan. There will also be a maintenance dosage consisting of 97mg sacubitril and 103mg valsartan. Again, this dose will be taken twice every day. As a maintenance dose is an extra dose, you should take it after making sure that you can tolerate the initial one.

    If you are not taking an ACE (angiotensin-converting enzyme) inhibitor or an ARB, then you should take an initial dose of 24mg sacubitril and 26mg valsartan two times per day. Doubling of the dose should occur every two to four weeks until the maintenance dose we mentioned above is reached.

    If it happens that you miss a dose, take it as soon as you can remember. But, if several hours have passed, take the next dose you have scheduled. Go to the emergency room if you take excess medicine.

    Side Effects

    The common side effects include dizziness and/or cough. If you take this oral drug and develop an allergy, get in touch with your physician quickly.


    If your heart doctor wants to prescribe this medication, tell them if you:

    • Are pregnant. If treatment was started when you were not pregnant, stop taking Entresto when you conceive.
    • Are breastfeeding.
    • Are allergic to either valsartan or sacubitril and other blood pressure medicines, ACEs and ARBs
    • Are diabetic or have a kidney disease as Entresto should not be combined with drugs that contain aliskiren.
    • Have a liver disease or hereditary angioedema
    • Are eating a low salt diet or dehydrated

    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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