Cardizem (Diltiazem)

(℞) Prescription Required

    Cardizem (Diltiazem) Dosage and Side Effects

    CARDIZEM, is used to treat high blood pressure and control chest pain (known as angina).

    Proper Use of this medication

    The typical oral dose for adults with chest pain or high blood pressure ranges from 120 milligrams (mg) to 540 mg a day.

    The immediate release tablets are typically given up to four times a day.

    The extended-release formula is given once a day and should not be crushed or chewed.

    Side Effects

    Common Side Effects

    CARDIZEM CD can cause side effects. You should tell your doctor if the following symptoms are severe or do not go away:



    •Dizziness or lightheadedness

    •Slow heartbeat





    •Nasal congestion


    Serious Side Effects

    CARDIZEM CD can cause serious side effects. You should call your doctor immediately if you experience:

    •Swelling of the face, lips, tongue, eyes, hands, arms, feet, lower legs, or ankles


    •Breathing or swallowing difficulties

    •Yellowing of the skin or eyes (jaundice)



    •Unusual bleeding or bruising

    •Extreme fatigue

    •Lack of energy

    •Loss of appetite

    •Pain in the upper right part of the stomach

    •Increase in frequency or severity of chest pain

    •Flu-like symptoms

    Warnings and Precautions

    CARDIZEM CD may prevent chest pain if taken regularly, but it does not stop chest pain once it starts.

    CARDIZEM CD controls high blood pressure and chest pain, but it does not cure them.

    It may take up to two weeks for you to experience the full benefit of this medicine.

    Your doctor will likely start you on a low dose of CARDIZEM CD and then gradually increase your dose.

    Your blood pressure and pulse will be checked regularly while taking CARDIZEM CD to determine your response to the drug.

    Before taking CARDIZEM CD, you should tell your doctor if you have ever had:

    •A heart attack

    •Any condition that causes food to move more slowly through your digestive system

    •Low blood pressure

    •Heart, liver, or kidney disease

    You should also tell your doctor if you plan to have any type of surgery, including dental surgery.

    Pregnancy and CARDIZEM CD

    There are not adequate studies to show that this drug is safe in pregnant women.

    CARDIZEM CD is excreted in breast milk, so women should not take it while breastfeeding.

    Interactions with this medication

    Many medications can interact with CARDIZEM CD.

    Tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you are taking, especially:

    •Atazanavir (Reyataz)

    •Beta blockers such as atenolol (Tenormin), labetalol (Trandate), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal)

    •Buspirone (BuSpar)

    •Benzodiazepines such as midazolam (Versed) and triazolam (Halcion)

    •Carbamazepine (Carbatrol, Epitol, Tegretol)

    •Cimetidine (Tagamet)

    •Digoxin (Lanoxin, Lanoxicaps)

    •Cyclosporine (Gengraf, Neoral, Sandimmune)

    •Rifampin (Rifadin, Rifamate, Rifater, Rimactane)

    •Lovastatin (Altoprev, Mevacor, Advicor)

    •Quinidine (Quinidex)

    Other CARDIZEM CD Interactions

    Grapefruit and grapefruit juice may interact with CARDIZEM CD. Your doctor may advise you to follow a low-sodium diet while taking CARDIZEM CD.

    This medication may impair your thinking and reaction time. Be especially careful when driving or performing any activity that may require you to be alert.

    You should also try to avoid exposure to sunlight or tanning beds. CARDIZEM CD can increase your skin's sensitivity to light and you may develop sunburns more easily.

    Other related Products

    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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