Prilosec (Omeprazole)

Prilosec (Omeprazole) Medication Information

Uses

Prilosec is a proton pump inhibitor (PPI) that is used to treat gastroesophageal reflux disease (GERD) and ulcers. 

Dosage

The capsules are available in several different strengths:

• 10 mg
• 20 mg
• 40 mg

Side Effects

The most common side effects of Prilosec include:

• Diarrhea
• Vomiting
• Flatulence
• Headache
• Stomach pain

Speak with your doctor for a full list of side effects that apply to you if you are taking Omeprazole.

Precautions

Prilosec like other PPIs can increase a patient's risk of developing an infection called C. difficile. 

There is a risk that taking Omeprazole can increase the chance of developing osteoporosis.

Prilosec has been linked to low magnesium in some patients. 

Interactions

The most common drug interactions with Prilosec are listed:

• Atazanavir
• Ketoconazole
• Clopidogrel
• Cilostazol
• Tacrolimus
• Methotrexate 

Speak with your doctor for more information and before starting a new medication with Omeprazole. 

Storage

Store at room temperature (59-86ºF). Protect capsules from moisture and store in a tight container.

Pharmacist Tips

• Prilosec should be swallowed whole, it should not be crushed or chewed.
• Prilosec is typically given for 4-8 weeks.
• Omeprazole capsule can be opened for those patients that have difficulty swallowing and put on apple sauce. 

Omeprazole FAQs

What happens if I take Prilosec every day?

There have been some concerns about taking Prilosec, and other PPIs for extended periods of time. There is a risk of infection, osteoporosis, dementia, and cancer. 

It is better to take Prilosec in the morning?

It is typically recommended to take Prilosec in the morning. 

How quickly does Prilosec work?

It can take several days for Prilosec to start work to reduce the acid in your stomach. 

Can I take Prilosec after eating?

Omeprazole can be taken with or without food, but it is typically preferred to be taken before eating.

Does Prilosec make you gain weight?

Omeprazole is not really associated with weight gain.

Related Drugs

• Dexilant
• Nexium
• Prevacid
• Protonix

Reference:

Prilosec {package insert}. Wilmington, DE: A. AstraZeneca Pharmaceuticals; 2012.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf