Vasotec (Enalapril)

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Vasotec 2.5mg

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Vasotec 5mg

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Vasotec is also marketed as Innovace
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Vasotec 10mg

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Vasotec 20mg

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Enalapril 10mg

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Enalapril 10mg
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Enalapril 20mg

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Enalapril 2.5mg

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Enalapril 5mg

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Enalapril 10mg

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Enalapril 20mg

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Manufactured by: Apotex Inc
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Enalapril 20mg
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Vasotec 2.5mg

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Vasotec 2.5mg
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Vasotec 5mg

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Vasotec 10mg

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Vasotec (Enalapril) Dosage and Side Effects

VASOTEC is used for reducing high blood pressure and treating patients with heart failure.

Warnings and Precautions

Serious Warnings and Precautions

VASOTEC should not be used during pregnancy. If you discover that you are pregnant while taking VASOTEC, stop the medication and please contact your physician as soon as possible.

This medicine may not be suitable for certain people. Tell your physician or pharmacist if you think any of the following applies to you:

  • You have previously taken VASOTEC or other medication of the same type—Angiotensin Converting Enzyme (ACE) inhibitors such as enalapril, lisinopril, captopril, and you were allergic or reacted badly to it, particularly if you experienced swelling of the face, lips, tongue, or throat, or had sudden difficulty breathing or swallowing. These are symptoms of conditions called hereditary angioedema or idiopathic angioedema.
  • Are taking a medicine that contains aliskiren, such as RASILEZ, used to lower high blood pressure. The combination with VASOTEC is not recommended.
  • Are taking an angiotensin receptor blocker (ARB). You can recognize an ARB because its medicinal ingredient ends in “-SARTAN”.
  • Are taking anti-cancer (temsirolimus, everolimus) or anti-rejection (sirolimus) medications. Use of ACE inhibitors, such asVASOTEC, with these drugs may increase the chance of having an allergic reaction (angioedema).
  • You should not take this medicine if you have been diagnosed with hereditary angioedema or idiopathic angioedema (angioedema of unknown cause).
  • Dizziness or drowsiness may occasionally occur when taking medication to lower blood pressure. Therefore, before you perform tasks which may require special attention (driving a car or operating dangerous machinery), wait until you know how you respond to your medicine.
  • You should be aware that black patients are at increased risk of these types of reactions to ACE inhibitors.
  • You are pregnant, breast-feeding or thinking of becoming pregnant. Taking VASOTEC during pregnancy can cause injury and even death to your developing baby. This medicine should not be used during pregnancy. If you become pregnant while taking VASOTEC, stop the medication and report to your physician as soon as possible. It is possible that VASOTEC passes into breast milk. You should not breast-feed while taking VASOTEC.
  • You suffer from low blood pressure (you may notice this as faintness or dizziness, especially when standing).
  • You are undergoing dialysis.
  • You have any of these conditions:
    • diabetes
    • heart or blood vessel disease
    • liver disease
    • kidney disease
  • You are receiving gold (sodium aurothiomalate) injections.
  • You are taking “water pills” or potassium supplements.
  • You use potassium containing salt substitutes with your food.

You should also inform your physician or pharmacist if you have recently suffered from excessive vomiting or diarrhea.

If you have diabetes and are taking oral medicines to treat diabetes or insulin, you should closely monitor for low blood glucose levels, especially during the first month of treatment with VASOTEC.

If you have to undergo any dental or other surgery, inform the dentist or the physician in charge that you are taking this medicine.

Remember: This medicine is prescribed for the particular condition that you have. Do not give this medicine to other people, nor use it for any other condition.

Do not use outdated medicine.

Side Effects

Along with its intended action, any medication, including VASOTEC, may cause side effects. Most people do not experience any problem when taking these medicines; but if you notice any of the following, have other side effects or if the condition persists or worsens, seek medical attention.

  • Dry cough, sore throat.
  • The initial dose may cause a greater fall in blood pressure than will occur following continued treatment. You may notice this as faintness or dizziness and it may help to lie down. If concerned, please consult your physician or pharmacist.

Interactions with this medication

Do not take any other medicines unless you have discussed the matter with your physician or pharmacist. Certain medications tend to increase your blood pressure, for example, non-prescription preparations for appetite control, asthma, colds, coughs, hay fever and sinus problems, or may also react badly with VASOTEC.

Your physician or pharmacist also needs to know if you are taking any other medication, whether on prescription or otherwise. It is particularly important to inform your physician or pharmacist if you are taking:

  • Diuretics or “water pills”; any other medicines to reduce blood pressure.
  • Diabetes medicine and/or insulin.
  • Blood pressure-lowering drugs, including diuretics (“water pills”), aliskiren-containing products (e.g. RASILEZ), or angiotensin receptor blockers (ARBs).
  • Potassium-containing medicines, potassium supplements.
  • Salt substitutes that contain potassium, as these may lead to increased levels of potassium in the blood which can be serious. In these cases, your physician may need to adjust the dosage of VASOTEC or monitor your blood level of potassium.
  • Lithium (a drug used to treat a certain kind of depression).
  • Certain pain and arthritis medicines, including gold therapy and non-steroidal anti-inflammatory drugs.
  • mTOR inhibitor (e.g., temsirolimus, sirolimus, everolimus) therapy. Taking these drugs together could increase the risk for an allergic reaction called angioedema.

Proper Use of this medication

Usual dose:

  • Take this medicine exactly as your physician ordered.
  • The absorption of this medicine is not affected by food; so it can be taken with or without a meal.
  • Try to take your medicine every day at the same time. This way it becomes easy to remember your doses.
  • The splitting of VASOTEC tablets is not advised.

For patients with high blood pressure:

Adults:

Your physician may adjust the dose according to your blood pressure response. The usual dose range is 10 mg to 40 mg per day given in a single dose or two divided doses. The maximum daily dose for VASOTEC oral administration is 40 mg.

Children (less than 16 years)

The usual starting dose is up to 5 mg once daily. Doses above 40 mg have not been studied.

For patients with congestive heart failure:

The initial dose is 2.5 mg taken once a day. Your physician will closely monitor you to determine the initial effect on your blood pressure. The usual daily dose is 5 mg to 20 mg given in a single dose or two divided doses. The maximum daily dose is 40 mg.

Overdose:

In case of an overdose, contact your physician, hospital emergency department or regional Poison Control Center immediately, even if there are no symptoms. The most likely symptom would be a feeling of lightheadedness or dizziness due to a sudden or excessive drop in blood pressure.

Missed dose:

If you miss a dose of this medicine, take it as soon as possible. However, if no more than six hours have elapsed since the missed dose, you may take that day's dose of medication and then go back to your regular dosing schedule. Do not take a double dose.

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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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