Uroxatral (Alfuzosin Hydrochloride)

Uroxatral is marketed as Xatral in Canada and the UK

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Alfuzosin XL 10mg

Product of United Kingdom
Manufactured by: UK Various Generics
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Alfuzosin XL 10mg
Product of United Kingdom
Manufactured by UK Various Generics
Top Brand Choice
Top Generic Choice

Xatral XL 10mg

Product of Turkey
Manufactured by: Sanofi Aventis
*Product image for reference use only.
Uroxatral is also marketed as Xatral XL
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Xatral XL 10mg
Product of Turkey
Manufactured by Sanofi Aventis
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Uroxatral (Alfuzosin) Dosage and Side Effects

UROXATRAL is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate). UROXATRAL helps relax the muscles in the prostate and bladder neck, making it easier to urinate.

Warnings and Precautions

You should not take UROXATRAL if you have moderate to severe liver disease.

There are many other drugs that can interact with UROXATRAL. Tell your doctor about all medications you use.

You should not take UROXATRAL if you are allergic to it, or if you have:

  • moderate to severe liver disease.

Some medicines can interact with UROXATRAL and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs:

  • imatinib;
  • isoniazid;
  • nefazodone;
  • an antibiotic--clarithromycin, telithromycin;
  • antifungal medicine--itraconazole, ketoconazole, posaconazole, voriconazole;
  • heart medication--nicardipine, quinidine;
  • antiviral medicine to treat hepatitis C or HIV/AIDS--atazanavir, boceprevir, cobicistat, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, telaprevir; or
  • medicines similar to UROXATRAL--doxazosin, prazosin, silodosin, tamsulosin, or terazosin.

To make sure UROXATRAL is safe for you, tell your doctor if you have:

  • low blood pressure, or a history of low blood pressure caused by taking medications;
  • kidney disease;
  • a personal or family history of long QT syndrome;
  • heart disease, angina (chest pain), high blood pressure;
  • coronary artery disease (hardened arteries);
  • a history of prostate cancer; or
  • a condition for which you take a nitrate medication (such as nitroglycerin).

UROXATRAL can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medicine.

Although UROXATRAL is not for use in women, this medicine is not expected to harm an unborn baby or a nursing baby. If you are a woman and you take UROXATRAL, tell your doctor if you are pregnant or breast-feeding.

UROXATRAL is not approved for use by anyone younger than 18 years old.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • new or worsening chest pain;
  • upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • penis erection that is painful or lasts 4 hours or longer.

Common side effects may include:

  • dizziness;
  • headache;
  • feeling tired; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Interactions with this medication

This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Drinking alcohol with this medicine can cause side effects.

Many drugs can interact with UROXATRAL, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with UROXATRAL. Give a list of all your medicines to any healthcare provider who treats you.

Proper Use of this medication

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

UROXATRAL is usually taken once daily just after a meal. Do not take UROXATRAL on an empty stomach. Take the medicine at the same time each day.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

UROXATRAL lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it. You may feel very dizzy when you first wake up. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

While using UROXATRAL, your blood pressure and prostate will need to be checked often.

Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, or heavy sweating. Call your doctor if you have a prolonged illness that causes diarrhea or vomiting.

Store at room temperature away from moisture, heat, and light.

Seek emergency medical attention or call the Poison Help line.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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