Trosec (Trospium Chloride)

BEFORE you use TROSEC talk to your doctor or pharmacist if:

• you have trouble emptying your bladder (slow urinary stream), because of the risk of urinary retention;
• you have delayed or slow emptying of your stomach because of the risk of gastric retention;
• you have ulcerative colitis (ulcers in the large intestine or colon), intestinal atony or myasthenia gravis (muscle weakness);
• you have an eye problem called “narrow-angle glaucoma” that is being treated;
• you have liver or kidney disease
• you have congestive heart failure, hypokalemia (low potassium), or other conditions which may increase the risk of TROSEC affecting your heart rate;
• you have heart disease;
• you are pregnant, planning on becoming pregnant or are breast feeding.

The safety and effectiveness of TROSEC has not been studied in children.

Although uncommon, TROSEC may cause blurred vision and/or drowsiness in some people. Until you know how TROSEC affects you, caution should be exercised when driving or operating heavy machinery.

Consumption of alcohol while taking TROSEC may make drowsiness worse.

Due to decreased sweating, heat prostration (overheating of the body) can occur when drugs such as TROSEC are used in a hot environment.

Common side effects:

In clinical studies, the most common side effects with TROSEC were dry mouth, constipation and abdominal pain.

Other side effects:

The following less common events may also occur with the use of TROSEC: dyspepsia (upset stomach), nausea, dizziness, flatulence, chest pain, dry eyes, blurred vision, increased heart rate, palpitation, urinary retention, and heat prostration.

Due to decreased sweating, heat prostration (overheating of the body) can occur when drugs such as TROSEC are used in a hot environment. Be sure to consume adequate amounts of liquid if you are in a hot environment for a prolonged period of time.

Tell your doctor or pharmacist if you have any side effects that bother you or don't go away.

The following events have rarely been reported during TROSEC use: Anaphylactic, Stevens-Johnson and toxic epidermal necrolysis reactions (rare, life-threatening, allergic reactions), angioedema (serious allergic reaction which can cause swelling of the face or throat), tachycardia (rapid heartbeat), syncope (fainting), myalgia (muscle pain), arthralgia (joint pain), rhabdomyolysis (destruction of muscle tissue), hallucinations, confusion, agitation, and hypertensive crisis (sudden, marked increase in blood pressure). If you think you are experiencing any of these rare effects, stop taking TROSEC immediately and go to the emergency room.

Drugs that may interact with TROSEC include: anticholinergic agents (such as amantadine, tricyclic antidepressants, quinidine, antihistamines, and disopyramide), beta agonists (such as salbutamol or formoterol), prokinetic agents (such as metoclopramide) and drugs that are eliminated by active renal secretion (such as digoxin, procainamide, pancuronium, morphine, vancomycin, metformin and tenofovir).

Tell your doctor or pharmacist about every medication you are taking including those you are taking without a prescription as well as any natural health products (herbal or vitamins).

Interactions with herbal medicines have not been studied.

Taking TROSEC with food reduces the amount of medication that will get into your body.

Overdose:

Overdosage with TROSEC may result in severe anticholinergic effects such as rapid and irregular heartbeat, flushed face, fever, ringing in the ears, and muscle spasms.

If you think you have taken an overdose of TROSEC, go to your nearest emergency room immediately. If possible, bring the package with you.

Missed dose:

If you miss a dose, take your next dose at the usual time (on an empty stomach at least 1 hour before your next meal). Do not double the next dose to make up for the missed dose.