Tegretol Suspension (Carbamazepine)

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Tegretol Suspension 100mg/5mL

Product of United Kingdom
Manufactured by: Novartis
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Tegretol Suspension 100mg/5mL
Product of United Kingdom
Manufactured by Novartis
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Tegretol Suspension 100mg/ 5mL

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Manufactured by: Novartis
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Tegretol Suspension 100mg/ 5mL
Product of Canada
Manufactured by Novartis
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Carbamazepine Suspension 100mg/ 5mL

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Manufactured by: Taro Pharmaceuticals Ltd.
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Carbamazepine Suspension 100mg/ 5mL
Product of Canada
Manufactured by Taro Pharmaceuticals Ltd.
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Tegretol Suspension (carbamazepine) Dosage and Side Effects

TEGRETOL has been prescribed for you by your doctor to reduce your number of seizures, to relieve the pain of trigeminal neuralgia, or to treat your acute mania or bipolar disorder.

Warnings and Precautions

Serious Warnings and Precautions

  • Blood: Although infrequently reported and very rarely fatal, serious adverse effects affecting blood cell counts have been observed during the use of TEGRETOL. Other side effects include: low white blood cell count, bone marrow depression, hepatitis and signs of liver failure such as jaundice (yellowing of the skin or eyes). Contact your doctor immediately if you are experiencing any of these symptoms. Close clinical and frequent laboratory supervision with your doctor should be maintained throughout treatment with TEGRETOL in order to detect as early as possible any possible signs of a blood disorder. Your doctor should discontinue TEGRETOL, if there is significant evidence of a bone marrow depression.
  • Skin: Serious and sometimes fatal skin reactions known as Toxic Epidermal Necrolysis (TEN) and Stevens-Johnson Syndrome (SJS), have been reported with TEGRETOL. Other serious skin reactions such as Drug Rash with Eosinophilia and Systemic Symptoms (DRESS), Acute Generalized Exanthematous Pustulosis (AGEP) and Maculopapular Rash have also been reported. Although very rare, serious forms of DRESS and AGEP may also lead to death. Some cases of these skin reactions have been genetically linked. Your doctor may recommend a blood test to determine if you belong to an at-risk population.
  • Contact your doctor immediately if you are developing any combination of:
    • a rash or any serious skin reactions such as red skin, blistering of the lips, eyes or mouth, and skin peeling accompanied by fever
    • swollen lymph nodes
    • joint pain
    • enlargement of the liver and/or the spleen
    • problems related to the lungs, kidneys, pancreas, heart, bone marrow, thymus, and colon
  • Your doctor will determine if it is indeed drug-related, and discontinue TEGRETOL in this case.
  • Cancer: Long-term toxicity studies in rats have indicated a possible cancer risk associated with carbamazepine. Before taking TEGRETOL, discuss with your doctor the potential benefits and possible risks of this treatment for you.

BEFORE you use TEGRETOL talk to your doctor or pharmacist:

  • About your medical conditions, especially if you have or have had any liver, kidney, heart or thyroid disease or blood disorders (including those caused by other drugs).
  • If you have a history, or family history, of bone disease or have taken antiepileptics (such as phenobarbital, phenytoin, primidone, oxcarbazepine, lamotrignine, sodium valproate and/or carbamezepine) for a prolonged period of time.
  • If you are taking delavirdine, a medicine used to treat HIV-1 infection.
  • About any allergies you may have, especially if you have ever shown any unusual sensitivity (rash or other signs of allergy) to oxcarbazepine or other drugs used to treat your condition. It is important to note that if you are allergic to TEGRETOL(carbamazepine), there is an approximately 1 in 4 (25%) chance that you could also have an allergic reaction to oxcarbazepine (TRILEPTAL).
  • If you are pregnant. Your doctor may recommend that you take folic acid before and during your pregnancy and vitamin K during the last weeks of pregnancy. Your doctor may also recommend that the newborn receive vitamin K and be observed for liver and gall bladder problems.
  • If you are planning on becoming pregnant to discuss the potential benefits against any potential hazards of TEGRETOL.
  • If you are a women taking hormonal contraceptive (birth control medicine). TEGRETOL may render this contraceptive ineffective. Therefore, you should use a different or additional non-hormonal method of contraception while you are taking TEGRETOL. This should help to prevent an unwanted pregnancy.
  • If you get irregular vaginal bleeding or spotting.
  • If you are breast-feeding. TEGRETOL is known to pass into breast milk. You must discuss with your doctor the benefits of breastfeeding against any possible risks to the infant. If you decide to breastfeed, the baby must be observed for liver and gall bladder problems, drowsiness, and allergic skin reactions.
  • About any other medicines (prescription and non-prescription) you are taking.
  • About your usual alcohol consumption.
  • If you have increased pressure in the eye (glaucoma).
  • If you have difficulty passing urine (urinary retention).
  • If you were told by your physician that you suffer from mental problems, a mental disorder called psychosis that may be accompanied by confusion or agitation, or have thoughts about suicide.

If any of the following apply to you, tell your doctor.

  • If an allergic reaction happens such as fever with lymph nodes swelling, rash or skin blistering, tell your doctor immediately or go to the emergency department at your nearest hospital.
  • If you experience an increase in the number of seizures, tell your doctor immediately.
  • If you experience any side effects such as drowsiness, headache, unsteadiness on the feet, double vision, dizziness, nausea or vomiting, consult your doctor.
  • If, at any time, you have thoughts of harming or killing yourself. A small number of people being treated with antiepileptic drugs have reported having such thoughts or behavior. Should this happen to you, or to those in your care if you are a caregiver or guardian, talk to your doctor immediately. Close observation by a doctor is necessary in this situation. Do not discontinue your medication on your own.
  • If you have kidney problems associated with low sodium blood level or if you have kidney problems and you are also taking certain medicines that lower sodium blood level (diuretics such as hydrochlorothiazide, furosemide).

TEGRETOL may affect male fertility or cause abnormal sperm.

Periodic eye examinations are recommended while taking TEGRETOL.

Do not drive a car or operate dangerous machinery until you are sure that TEGRETOL does not cause dizziness, drowsiness, sleepiness, blurred or double vision, affect your muscular coordination or affect your alertness.

Side Effects

Side effects may include:

  • purple or reddish-purple bumps that may be itchy
  • trembling, uncontrolled body movements, muscle spasm, loss of muscle coordination, weakness
  • agitation or hostility (especially in the elderly), depression with restlessness, nervousness or other mood or mental changes, changes in behaviour, confusion, headache, memory loss
  • blurred vision, double vision, itching with redness and swelling of the eye (conjunctivitis), uncontrolled eye movements
  • difficulty speaking or slurred speech, taste disturbances, dry mouth, red and sore tongue, mouth sores
  • ringing or other unexplained sounds in the ears, decreased hearing
  • numbness, tingling in hands and feet
  • unusual secretion of breast milk, breast enlargement in men, sexual disturbances (erectile dysfunction), male infertility
  • increased sensitivity of the skin to sun, alterations in skin pigmentation, acne, increased sweating
  • reactivation of herpes virus infection (can be serious when the immune system is depressed)
  • complete loss of the nails, loss of hair, excessive body and facial hair
  • vomiting, nausea, loss of appetite, constipation, diarrhea, abdominal pain
  • dizziness, sleepiness, unsteadiness, drowsiness, fatigue
  • weight gain
  • aching joints or muscles

Long-term use of antiepileptics such as carbamazepine, phenobarbital, phenytoin, primidone, oxcarbazepine, lamotrigine and sodium valproate is associated with a risk of decreased bone mineral density that may lead to weakened or brittle bones, or fracture.

If any of these affects you severely, contact your doctor

TEGRETOL can cause abnormal blood test results. Your doctor will decide when to perform blood tests and will interpret the results.

Interactions with this medication

Tell your doctor or pharmacist if you are taking or have recently taken any prescription, non-prescription medicines or natural health products. It is particularly important for TEGRETOL, since many other medicines interact with it.

You may need a change in your dose or, sometimes, to stop one of these other medicines.

Irregularity of the menstrual period may occur in women taking hormonal contraceptives (birth control medicines) and TEGRETOL. The hormonal contraceptive may become less effective and you should use another contraceptive method (non-hormonal).

  • Avoid alcohol consumption when taking TEGRETOL.
  • Do not drink grapefruit juice or eat grapefruit since this can increase the effect of TEGRETOL. Other juices, like orange juice or apple juice, do not have this effect.

Proper Use of this medication

Usual dose:

Dosage should be individualised. It is very important that you take TEGRETOL exactly as your doctor instructed.

  • Never increase or decrease the recommended dose of TEGRETOL you are taking unless your doctor tells you to.
  • If you are taking TEGRETOL, do not suddenly stop taking it without first checking with your doctor. Your doctor will tell you if and when you can stop taking this medicine.
  • TEGRETOL Tablets, CHEWTABS and Suspension should be taken in 2-4 divided doses daily, with meals whenever possible.
  • TEGRETOL CR tablets should be swallowed unchewed with a little liquid during or after a meal.
  • Shake TEGRETOL Suspension well before you take it or else you may not receive the correct dose.

Adults and Children Over 12 Years of Age:

Initial dose 100 to 200 mg once or twice a day. Your doctor will decide the best dosage for you. Always follow your doctor’s instructions.

For the treatment of trigeminal neuralgia, the maximum dose is 1200 mg a day.

Children 6-12 Years of Age:

Initial dose 100 mg in divided doses on the first day. Your doctor will decide the best dosage for you. Always follow your doctor’s instructions.


In case of drug overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.

Missed dose:

If you miss a dose, take your TEGRETOL as soon as possible. However, if the time is close to the next dose, do not take the missed dose and return to your regular dosing schedule. Do not double the dose to make up for the forgotten dose.

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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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