Tarka (Trandolapril / Verapamil Hydrochloride)

(℞) Prescription Required

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Tarka 2mg/180mg

Product of Australia
Manufactured by: Abbott Laboratories Ltd.
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Tarka 2mg/180mg
Product of Australia
Manufactured by Abbott Laboratories Ltd.
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Tarka 4mg/240mg

Product of Australia
Manufactured by: Abbott Laboratories Ltd.
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Tarka 4mg/240mg
Product of Australia
Manufactured by Abbott Laboratories Ltd.
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Tarka 2mg/180mg

Product of Turkey
Manufactured by: Abbott Laboratories Ltd.
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Tarka 2mg/180mg
Product of Turkey
Manufactured by Abbott Laboratories Ltd.
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Tarka 4mg/240mg

Product of Turkey
Manufactured by: Abbott Laboratories Ltd.
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Tarka 4mg/240mg
Product of Turkey
Manufactured by Abbott Laboratories Ltd.
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Tarka (trandolapril/verapamil SR) Dosage and Side Effects

TARKA is a combination medicine used to treat high blood pressure (hypertension).

Warnings and Precautions

Do not use if you are pregnant. Stop using this medicine and tell your doctor right away if you become pregnant.

If you have diabetes, do not use TARKA together with any medication that contains aliskiren (such as Amturnide, Tekturna, Tekamlo).

You should not use this medicine if you are allergic to trandolapril or verapamil, or if you have:

  • certain serious heart conditions, especially "sick sinus syndrome" or "AV block" (unless you have a pacemaker);
  • a heart rhythm disorder;
  • low blood pressure; or
  • if you are allergic to any other ACE inhibitor, such as benazepril, captopril, fosinopril, enalapril, lisinopril, moexipril, perindopril, quinapril, or ramipril.

If you have diabetes, do not use TARKA together with any medication that contains aliskiren (such as Amturnide, Tekturna, Tekamlo).

You may also need to avoid taking TARKA with aliskiren if you have kidney disease.

To make sure TARKA is safe for you, tell your doctor if you have:

  • kidney disease (or if you are on dialysis);
  • liver disease;
  • congestive heart failure;
  • diabetes;
  • a nerve-muscle disease such as muscular dystrophy; or
  • a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.

Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. TARKA can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

TARKA can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using TARKA.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • sudden weakness or ill feeling, fever, chills, sore throat, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms;
  • upper stomach pain, and jaundice (yellowing of the skin or eyes);
  • chest pain, fast, slow, or uneven heart rate;
  • lung problems--anxiety, sweating, pale skin, severe shortness of breath, wheezing, gasping for breath, cough with foamy mucus;
  • high potassium--nausea, slow or unusual heart rate, weakness, loss of movement; or
  • kidney problems--little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath.

Common side effects may include:

  • cough;
  • cold symptoms such as stuffy nose, sneezing, sore throat;
  • headache, dizziness;
  • chest pain, back pain;
  • constipation;
  • feeling tired; or
  • abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Interactions with this medication

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

If you also take disopyramide, avoid taking it within 48 hours before or 24 hours after you take TARKA.

Do not use potassium supplements or salt substitutes while you are taking TARKA, unless your doctor has told you to.

Many drugs can interact with TARKA. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

  • colchicine;
  • a diuretic or "water pill";
  • gold injections to treat arthritis;
  • insulin or oral diabetes medicine;
  • lithium;
  • St. John's wort;
  • cholesterol-lowering medicine--atorvastatin, lovastatin, simvastatin, and others;
  • an antibiotic--clarithromycin, erythromycin, telithromycin;
  • antifungal medicine--itraconazole, ketoconazole, posaconazole, voriconazole;
  • heart or blood pressure medicine--digoxin, digitalis, disopyramide, flecainide, metoprolol, propranolol, quinidine;
  • antiviral medicine to treat hepatitis or HIV/AIDS--atazanavir, boceprevir, cobicistat, delavirdine, efavirenz, ritonavir, and others;
  • medicine to prevent organ transplant rejection--cyclosporine, everolimus, sirolimus, tacrolimus, temsirolimus;
  • NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others;
  • seizure medicine--carbamazepine, phenytoin; or
  • tuberculosis medicine--isoniazid, rifampin.

This list is not complete and many other drugs can interact with TARKA. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Proper Use of this medication

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

TARKA works best if you take it with food.

Your blood pressure will need to be checked often.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking TARKA. This can lead to very low blood pressure, electrolyte disorders, or kidney failure.

If you need surgery, tell the surgeon ahead of time that you are using TARKA. You may need to stop using the medicine for a short time.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.

Seek emergency medical attention or call the Poison Help.

Overdose symptoms may include slow heart rate, weak pulse, muscle weakness, tingly feeling, seizure (convulsions), feeling light-headed, or fainting.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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