Priligy (Dapoxetine) Dosage and Side Effects
Dapoxetine, marketed as Priligy and Westoxetin, among and other brands, is the first compound developed specially for the treatment of premature ejaculation (PE) in men 18–64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a consequence promoting ejaculatory delay. As a member of selective serotonin reuptake inhibitor (SSRI) family, dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Its fast-acting property makes it suitable for the treatment of PE but not as an antidepressant.
Proper Use of this medication
One tablet should be taken one hour before sex. It can be taken with or without food. You should not take alcohol when you use Priligy. Never take more than one tablet within a 24 hour period. Priligy is only licensed in men between the ages of 18 and 64 who have had PE for at least six months.
The most common side effects are nausea, dizziness, headache, fainting and diarrhoea. A full list of side effects will come with your medication or you can click here to read the manufacturers advice. If you feel dizzy or faint after taking Priligy then you should not drive, operate heavy machinery or undertake hazardous activities.
Warnings and Precautions
Priligy is only advised for men who ejaculate in less than two minutes of penetration. It should not be taken by men who have heart disease, those who have a tendency to faint or in those who take certain medicines (your doctor will be aware of which medicines this applies to). This is because more serious side effects can occur.
Interactions with this medication
Many men that have PE also suffer from erectile dysfunction (ED). Treatment for these patients should consider the drug-drug interaction between dapoxetine and PDE5 inhibitors such as tadalafil (Cialis) or sildenafil (Viagra). In Dresser study (2006), plasma concentration of 24 subjects was obtained. Half of the sample pool were treated with dapoxetine 60 mg + tadalafil 20 mg; the other half were treated with dapoxetine 60 mg + sildenafil 100 mg. These plasma samples were then analyzed using liquid chromatography-tandem mass spectrometry. The results showed that dapoxetine does not alter the pharmacokinetic of tadalafil or sildenafil.
Ethanol doesn't affect the pharmacokinetics of dapoxetine when taking concurrently with dapoxetine.
Other related products
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.