Hydrodiuril (Hydrochlorothiazide)

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Hydrochlorothiazide 12.5mg

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Manufactured by: Apotex Inc
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Hydrochlorothiazide 12.5mg
Product of Canada
Manufactured by Apotex Inc
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Hydrochlorothiazide 25mg

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Manufactured by: Teva Pharmaceuticals
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Hydrochlorothiazide 25mg
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Manufactured by Teva Pharmaceuticals
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Hydrochlorothiazide 50mg

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Manufactured by: Teva Pharmaceuticals
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Hydrochlorothiazide 50mg
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Manufactured by Teva Pharmaceuticals
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Hydrochlorothiazide 12.5mg

Product of India
Manufactured by: Cipla Ltd
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Hydrochlorothiazide 12.5mg
Product of India
Manufactured by Cipla Ltd
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Hydrodiuril (Hydrochlorothiazide) Dosage and Side Effects

HYDRODIURIL is a prescription diuretic ("water pill") that's used to treat high blood pressure and other conditions.

Proper Use of this medication

HYDRODIURIL comes in tablet form and is meant to be taken orally.

HYDRODIURIL can be taken with or without food.

In adults being treated for hypertension, the usual dose is 12.5 to 50 mg once daily.

If the medicine has been prescribed for edema, most adults will take 25 to 100 mg once a day or in divided doses.

Your doctor will likely advise you to take your medication at the same time each day.

Don't stop taking HYDRODIURIL even if you feel well; your blood pressure may still be high even when you don’t feel sick.

It’s not a good idea to take HYDRODIURIL within four hours of going to bed since it may result in your having to urinate during the night.

If your condition doesn’t improve and/or gets worse, let your doctor know right away. Your doctor may need to adjust the dose.

HYDRODIURIL and Overdose

Signs of an overdose may include:

  • Nausea
  • Weakness
  • Dizziness
  • Dry mouth
  • Thirst
  • Muscle pain/weakness

In the event of an accidental overdose, call 911 immediately or contact a poison control center.

HYDRODIURIL and Missed Dose

If you miss a dose, don’t take extra medication to make up for it.

In some cases, you may be able to take the missed dose as soon as you remember. However, if it's almost time for the next scheduled dose, you should skip the one you missed.

If you're not sure what to do, contact your doctor or pharmacist to avoid overdosing.

Side Effects

The most common side effects associated with HYDRODIURIL include:

  • Thirst
  • Muscle weakness
  • Constipation
  • Blurred vision
  • Dizziness
  • Photosensitivity

If you notice any of the following severe side effects, stop taking HYDRODIURIL and call your doctor immediately:

  • Severe allergic reaction (rash, hives, difficulty breathing, swelling of face, lips, tongue, or throat)
  • Severe stomach pain, loss of appetite, dark urine, or clay colored stools
  • Bleeding or bruising that seems unusual
  • A severe skin rash which includes peeling skin
  • Heartbeats that are fast or uneven
  • Tingling or numbness
  • Skin or eye yellowing (jaundice)

Warnings and Precautions

To ensure that you can safely take HYDRODIURIL, it’s important that you tell your doctor if you are suffering from any of the following:

  • Kidney disease
  • Liver disease
  • Glaucoma
  • Asthma or allergies
  • Gout
  • Diabetes
  • An allergy to sulfa drugs or penicillin

Talk to your doctor immediately if you experience any of the following while taking HYDRODIURIL:

  • Seizures or convulsions
  • Decreased urine
  • Drowsiness
  • Dry mouth/excessive thirst
  • Increased heart rate
  • Muscle pain
  • Nausea
  • Vomiting
  • Fatigue
  • Weakness

These may be symptoms of a condition called hypokalemia or potassium loss. HYDRODIURIL can lower potassium levels.

While taking HYDRODIURIL, you may need to take potassium supplements, decrease salt intake, and eat a diet rich in potassium with foods like bananas.

Stop using HYDRODIURIL if you have:

  • Blurred vision
  • Difficulty reading
  • Eye pain

These may be symptoms of a serious eye problem. Your doctor may refer you to an ophthalmologist.

HYDRODIURIL can cause dizziness. Do not drive or use machinery while taking HYDRODIURIL.

HYDRODIURIL might increase your blood sugar levels, so it’s important that if you have diabetes, you check your blood sugar levels regularly.

You should also avoid sun exposure, as HYDRODIURIL can increase sun sensitivity.

If you go out in hot weather, especially if you are exercising, avoid becoming overheated or dehydrated.

HYDRODIURIL and Pregnancy

Be sure to let your doctor know if you're pregnant or are planning to become pregnant while on HYDRODIURIL.

Thiazides like HYDRODIURIL may increase the risk of fetal or neonatal jaundice and low platelet levels, and perhaps lead to other adverse reactions.

If taken during pregnancy, HYDRODIURIL could be toxic to the fetus, leading to death. Stop taking HYDRODIURIL as soon as you find out you're pregnant.

You shouldn't use HYDRODIURIL while breastfeeding since it may pass into your breast milk and could harm a nursing baby. Be sure your doctor knows that you're breastfeeding before taking HYDRODIURIL.

Interactions with this medication

It's very important to let your doctor know about all drugs you're taking, including illegal drugs, any over-the-counter (OTC) drugs, and any herbs or supplements.

Before taking HYDRODIURIL, tell your doctor if you're using any of the following drugs:

  • Lithium/Eskalith (Lithobid)
  • Digoxin/Lanoxin
  • Cholestyramine/Prevalite
  • Cholestyramine (Questran)
  • Colestipol/Colestid
  • Phenobarbital (Luminal)
  • Secobarbital (Seconal)

If you're also taking digoxin, the potassium-lowering effects of HYDRODIURIL may worsen cardiac arrhythmias.

Cholestyramine and colestipol may decrease the absorption of HYDRODIURIL. If you’re taking either one, do so at least four hours before or after taking HYDRODIURIL.

Tell your doctor if you take cold and pain medicine, muscle relaxers, or medication for seizures, depression, or anxiety. These are known to make you light headed and may increase the side effects of HYDRODIURIL.

Drugs that may interact with acyclovir include steroids such as:

  • Prednisone (Deltasone, Meticorten, Sterapred, others)
  • Betamethasone (Celestone)
  • Budesonide (Entocort, Uceris)
  • Cortisone (Cortone)
  • Dexamethasone (Decadron, Dexpak, Dexasone, others)
  • Fludrocortisone (Florinef)
  • Hydrocortisone (Cortef, Hydrocortone)
  • Methylprednisolone (Solu-Medrol, Meprolone, others)
  • Prednisolone (Prelone, others)
  • Triamcinolone (Aristocort, Azmacort)

In addition, other blood pressure medications as well as NSAIDs (non-steroidal anti-inflammatory drugs) may interact with HYDRODIURIL. Examples of NSAIDs include:

  • Aspirin
  • Ibuprofen (Advil, Motrin)
  • Naproxen (Aleve, Naprosyn)
  • Naprelan
  • Treximet
  • Celecoxib/Celebrex
  • Diclofenac/Arthrotec (Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid)
  • Solareze
  • Indomethacin/Indocin
  • Meloxicam/Mobic

Finally, other medications that may interact with HYDRODIURIL include:

  • Insulin or oral diabetes medication
  • Corticotropin (ACTH, H.P., Acthar Gel)

If you're taking any of these medications, or others, your doctor may need to change the doses of these medications or monitor you carefully for side effects.

Other related products

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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