Aptiom (Eslicarbazepine)

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Aptiom 200mg

Product of United Kingdom
Manufactured by: Eisai
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Aptiom is also marketed under the name Zebinix
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Aptiom 200mg
Product of United Kingdom
Manufactured by Eisai
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Aptiom 800mg

Product of United Kingdom
Manufactured by: Eisai
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Aptiom is also marketed under the name Zebinix
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Aptiom 800mg
Product of United Kingdom
Manufactured by Eisai
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Aptiom 200mg

Product of Canada
Manufactured by: Sunovion Pharmaceuticals
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Aptiom 200mg
Product of Canada
Manufactured by Sunovion Pharmaceuticals
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Aptiom 400mg

Product of Canada
Manufactured by: Sunovion Pharmaceuticals
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Aptiom 400mg
Product of Canada
Manufactured by Sunovion Pharmaceuticals
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Aptiom 600mg

Product of Canada
Manufactured by: Sunovion Pharmaceuticals
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Aptiom 600mg
Product of Canada
Manufactured by Sunovion Pharmaceuticals
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Aptiom 800mg

Product of Canada
Manufactured by: Sunovion Pharmaceuticals
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Product of Canada
Manufactured by Sunovion Pharmaceuticals
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Eslicarbazepine 400mg

Product of India
Manufactured by: Sun Pharmaceuticals Ltd
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Eslicarbazepine 400mg
Product of India
Manufactured by Sun Pharmaceuticals Ltd
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Eslicarbazepine 800mg

Product of India
Manufactured by: Sun Pharmaceuticals Ltd
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Eslicarbazepine 800mg
Product of India
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Aptiom (Eslicarbazepine) Product Information

Aptiom is a medication for treating people who suffer from partial-onset seizures. It is an anticonvulsant  that can be prescribed with other medications to treat epilepsy.

This medicine is able to reduce nerve impulses that are known to trigger seizures and pain, and  it can be used alone or with other medicines to control partial onset seizures in children and adults. Children should be at least four years old to be given this medication.

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The brand medication is manufactured by Sunovion Pharmaceuticals Inc. and it is available in four dosages: 200mg, 400mg, 600mg and 800mg strength. Another brand name of the medication is Zebinix, and it is manufactured by a company called Eisai. There are also generics, produced by other manufacturers available; the generic tablets are called Eslicarbazepine.

Orders shipped from the UK or Canada take an estimated 7-10 business days in shipping to the US while orders shipped from other locations take approximately 10-18 business days in transit once shipped. You will get notified by email when your order has been dispensed and shipped.

Aptiom (Eslicarbazepine) Medication Information

Uses

Aptiom is indicated as adjunctive treatment of partial-onset seizures.

Dosage

There are oral tablets available in several different strengths:

  • 200 mg
  • 400 mg
  • 600 mg
  • 800 mg

Side Effects

The most common side effects of Aptiom include:

  • Dizziness
  • Somnolence
  • Nausea/vomiting
  • Headache
  • Diplopia
  • Fatigue
  • Vertigo
  • Ataxia
  • Blurred vision
  • Tremor 

Speak with your doctor or pharmacist for a full list of side effects that applies to you.

Precautions

Monitor for suicidal thoughts or behavior.

Monitor for dermatologic reactions and discontinue in the case of serious dermatologic reaction.

Monitor sodium levels in patients at risk or patients experiencing hyponatremia symptoms.

Monitor for dizziness, disturbance in gait and coordination, somnolence, fatigue, cognitive dysfunction, and visual changes. Use caution when driving or operating machinery.

Interactions

Some of the common drug interactions with Aptiom:

  • Carbamazepine
  • Phenytoin
  • Phenobarbital
  • Primidone
  • Hormonal contraceptive

For a more complete list speak with your doctor or pharmacist 

Storage

Store at controlled room temperature (68º-77ºF) 

Pharmacist Tips

  • Aptiom may increase the risk of suicidal thoughts and behavior and you need to be alert for the emergence or worsening of symptoms of depression, any unusual changes in mood or behavior, or the emergence of suicidal thoughts, behavior, or thoughts about self-harm. Report behaviors of concern immediately to healthcare providers
  • There is a risk of potentially fatal serious skin reactions. Consult with their healthcare provider immediately if a skin reaction occurs during treatment with Aptiom. 
  • Aptiom may reduce serum sodium concentrations, especially if you are taking other medications that can lower sodium. Report symptoms of low sodium such as nausea, tiredness, lack of energy, irritability, confusion, muscle weakness/spasms, or more frequent or more severe seizure.

Aptiom FAQs

Can I take this with food?

Can be taken with or without food

 

Can I take this if I am pregnant or breastfeeding?

There are no adequate and well-controlled studies in pregnant women. Physicians are advised to recommend that pregnant patients taking Aptiom enroll in the North American Antiepileptic Drug Pregnancy Registry.

Eslicarbazepine is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants from Aptiom, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Related Drugs

Reference:

Aptiom {package insert}. Marlborough, MA: Sunovion Pharmaceuticals Inc.; 2013.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022416s000lbl.pdf

PharmD Medical Writer

Author: Dr. Larisa Roybal, PharmD

Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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