Norflex (Orphenadrine)

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take this medicine with a full glass of water.

Do not crush, chew, or break the extended-release tablet. Swallow the pill whole. Breaking or crushing the pill may cause too much of the drug to be released at one time.

NORFLEX is only part of a complete program of treatment that may also include rest, physical therapy, or other pain relief measures. Follow your doctor's instructions.

NORFLEX may be habit-forming and should be used only by the person it was prescribed for. NORFLEX should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Store NORFLEX at room temperature away from moisture, heat, and light.

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of NORFLEX can be fatal.

Overdose symptoms may include blurred vision, fast heart rate, confusion, weak or shallow breathing, cold or clammy skin, feeling like you might pass out, or seizure (convulsions).

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using NORFLEX and call your doctor at once if you have any of these serious side effects:

• fast, pounding, or uneven heartbeats;
• confusion, anxiety, agitation, tremors, hallucinations;
• seizure (convulsions); or
• urinating less than usual or not at all.

Less serious side effects may include:

• dry mouth or throat;
• blurred vision, dilated pupils;
• headache;
• drowsiness, dizziness;
• nausea, vomiting, constipation; or
• weakness.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

Do not crush, chew, or break the extended-release tablet. Swallow the pill whole. Breaking or crushing the pill may cause too much of the drug to be released at one time.

NORFLEX may be habit-forming and should be used only by the person it was prescribed for. NORFLEX should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

NORFLEX can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol, which can increase some of the side effects of NORFLEX.

Do not take this medication if you are allergic to NORFLEX, or if you have:

• problems with urination;
• enlarged prostate;
• glaucoma;
• a blockage in your stomach or intestines;
• trouble swallowing; or
• myasthenia gravis.

Before taking NORFLEX, tell your doctor if you are allergic to any drugs, or if you have:

• heart disease;
• a heart rhythm disorder; or
• coronary artery disease.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take NORFLEX.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether NORFLEX passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

NORFLEX can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol, which can increase some of the side effects of NORFLEX.

Cold or allergy medicine, narcotic pain medicine, sleeping pills, and medicine for seizures, depression or anxiety can add to sleepiness caused by NORFLEX. Tell your doctor if you regularly use any of these medicines, or any other muscle relaxer.

Before taking NORFLEX, tell your doctor if you are taking any of the following medicines:

• atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
• bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);
• glycopyrrolate (Robinul);
• mepenzolate (Cantil);
• bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); or
• irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine).

This list is not complete and there may be other drugs that can interact with NORFLEX. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.