Zyvox (Linezolid) Dosage and Side Effects
ZYVOX is a medicine your doctor has chosen to treat your bacterial infection. ZYVOX belongs to the class of medicines called antibiotics. It works by stopping the production of some bacterial proteins needed for growth, leading to bacterial death and reduction of the infection.
Warnings and Precautions
BEFORE you use ZYVOX talk to your doctor or pharmacist if:
you have a history of high blood pressure.
you are taking any cold or flu remedies or decongestants containing pseudoephedrine.
you are taking any antidepressants especially those known as serotonin re-uptake inhibitors.
you are taking any other medicines, including those you have bought without a prescription.
you have a history of anemia (low hemoglobin), thrombocytopenia (low platelets), neutropenia (low white blood cells) or any other blood related disorders.
you have a history of bleeding problems.
you ever had any unusual or allergic reaction to ZYVOX or its ingredients (such as preservatives or dyes).
you are pregnant or trying to become pregnant.
you are breast-feeding.
you have a history of seizures or convulsions.
you have diabetes, as ZYVOX may cause low blood sugar (hypoglycemia).
Like all medicines, ZYVOX can cause some unwanted effects in some people. These usually do not last very long and will not mean that you have to stop taking the tablets.
More common side effects reported include: headache, diarrhea, nausea, vomiting, dizziness, taste alteration , fungal infections, especially vaginal or white patches in mouth, tongue, or throat (oral “thrush”), tongue discoloration and fever.
Less common side effects reported include: insomnia, constipation, rash, dry mouth, stomach discomfort, increased thirst, hyperglycemia (e.g. high blood sugar), hypoglycemia (e.g. low blood sugar), ringing in the ear and high blood pressure.
If you experience symptoms such as severe diarrhea (bloody or watery) with or without fever, abdominal pain, or tenderness, you may have Clostridium difficile colitis (bowel inflammation). If this occurs, stop taking ZYVOX and contact your healthcare professional immediately.
If you notice any other side effects after taking this medicine that do not appear in the list above, tell your doctor or pharmacist.
Interactions with this medication
Drugs that may interact with ZYVOX include:
medications containing sympathomimetic agents such as pseudoephedrine HCl, often found in cold remedies and decongestants.
serotonin re-uptake inhibitors or other antidepressants.
ZYVOX may react with a substance, which is naturally present in some foods called tyramine. Foods or beverages with high tyramine content should be avoided while taking ZYVOX. Quantities of tyramine consumed should be less than 100 mg per meal. Foods high in tyramine content include those that may have undergone protein changes by aging, fermentation, pickling, or smoking to improve flavor, such as aged cheeses (0 to 15 mg tyramine per 28 g); fermented or air-dried meats (0.1 to 8 mg tyramine per 28 g); sauerkraut (8 mg tyramine per 224 g); soy sauce (5 mg tyramine per 1 teaspoon); tap beers (4 mg tyramine per 360 mL); red wines (0 to 6 mg tyramine per 240 mL). The tyramine content of any protein-rich food may be increased if stored for long periods or improperly refrigerated. If you develop a throbbing headache after eating or drinking, tell your doctor or pharmacist.
Proper Use of this medication
Usual adult dose:
ZYVOX (tablets, injection and oral suspension):
Each dose should be taken twice daily (every 12 hours). ZYVOX may be taken with or without food.
The safety and effectiveness of ZYVOX in children has not been established.
A course of treatment usually lasts 10 to 14 days, but may last up to 28 days.
Remember: This medicine has been prescribed for you personally and you should not let other people use it. It may harm them, even if their symptoms are the same as yours.
In case of drug overdose, contact a healthcare practitioner, hospital emergency department or your regional poison control centre, even if there are no symptoms.
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule as prescribed by your doctor. Do not take double doses to make up for missing a dose.
Other related products
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.