Wellbutrin (Bupropion Hydrochloride) Dosage and Side Effects WELLBUTRIN is the brand name for bupropion, a prescription drug that’s used to treat depression. It’s also used to treat seasonal affective disorder (SAD), a type of depression that usually strikes in the fall and winter. WELLBUTRIN, like other antidepressants, is required to carry a black-box warning … Continue reading Wellbutrin SR (Bupropion Hydrochloride)