Trilafon (perphenazine) Dosage and Side Effects
TRILAFON is an anti-psychotic medicine in a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing the actions of chemicals in your brain. TRILAFON is used to treat psychotic disorders such as schizophrenia. It is also used to control severe nausea and vomiting.
Warnings and Precautions
You should not use TRILAFON if you have liver disease, brain damage, bone marrow depression, a blood cell disorder, or if you are also using large amounts of alcohol or medicines that make you sleepy.
Call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous side effects.
You should not use this medicine if you are allergic to any phenothiazine (TRILAFON, chlorpromazine, prochlorperazine, promethazine, thioridazine, Compazine, Phenergan, Mellaril, Thorazine, and others), or if you have:
- liver disease;
- brain damage;
- bone marrow depression;
- a blood cell disorder (such as low platelets or low red or white blood cell counts); or
- if you are also using large amounts of alcohol or medicines that make you sleepy.
TRILAFON is not approved for use in psychotic conditions related to dementia. TRILAFON may increase the risk of death in older adults with dementia-related conditions.
To make sure TRILAFON is safe for you, tell your doctor if you have:
- severe or untreated depression;
- heart disease or high blood pressure;
- kidney disease;
- severe asthma, emphysema, or other breathing problem;
- a history of seizures;
- Parkinson's disease;
- past or present breast cancer;
- adrenal gland tumor (pheochromocytoma);
- enlarged prostate or urination problems;
- low levels of calcium in your blood (hypocalcemia);
- glaucoma; or
- if you have ever had a serious side effect while using TRILAFON or another phenothiazine.
Tell your doctor if you will be exposed to extreme heat or cold, or to insecticide poisons while you are taking TRILAFON.
Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking TRILAFON, do not stop taking it without your doctor's advice.
TRILAFON can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these signs of a serious movement disorder:
- tremors or shaking in your arms or legs;
- uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); or
- any new or unusual muscle movements you cannot control.
Also call your doctor at once if you have:
- feeling restless, jittery, or agitated;
- confusion, unusual thoughts or behavior;
- seizure (convulsions);
- extreme drowsiness or dizziness, feeling like you might pass out;
- severe bloating or stomach cramps;
- little or no urinating;
- slow heart rate, weak pulse, weak or shallow breathing;
- sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing; or
- severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, fast or uneven heartbeats.
Older adults may be more likely to have side effects from this medication.
Common side effects may include:
- mild dizziness or drowsiness;
- blurred vision, headache;
- sleep problems (insomnia), strange dreams;
- loss of appetite, vomiting, diarrhea, constipation;
- increased sweating or urination;
- dry mouth or stuffy nose;
- breast swelling or discharge; or
- mild itching or skin rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Interactions with this medication
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Proper Use of this medication
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.
Other related products
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.