Salagen (Pilocarpine) Dosage and Side Effects
SALAGEN tablets are used to treat dry mouth and/or your dry eyes caused by radiotherapy in people with head and neck cancer or by Sjogren's syndrome (a condition that affects the immune system and causes dryness of certain parts of the body such as the eyes and mouth). SALAGEN tablets cause your salivary glands and your tear glands to make more of your natural saliva and tears.
Proper Use of this medication
Usual adult dose:
Take SALAGEN tablets three or four times a day as directed by your doctor. Your doctor may recommend a reduced dosage if you suffer from liver or kidney problems. Do not take more than six tablets (30mg) per day.
Take SALAGEN tablets with or without food.
Do not chew or bite on the tablet.
In case of drug overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.
Overdose symptoms include salivation, sweating, vomiting, difficulty breathing, changes in blood pressure, diarrhea, nausea and shock. Mental confusion and an irregular heartbeat can also occur.
If you miss a dose of SALAGEN, take the next dose when you normally would. Do not take more than two tablets at a time.
Most side effects that could occur have been generally mild or of moderate intensity. The possible side effects are:
- mild to moderate sweating
- nausea (feeling sick) and vomiting
- passing urine more often
- problems with digestion
- runny eyes
- runny nose
- flushing (redness in face)
Warnings and Precautions
BEFORE you use SALAGEN, talk to your doctor or pharmacist if you have:
- an abnormal heart beat or have had heart failure
- either high blood pressure or low blood pressure
- asthma or difficulty breathing, bronchitis or emphysema
- liver disease such as hepatitis, cirrhosis or other
- blurred vision, difficulty seeing at night, glaucoma or inflammation of the eye (iritis)
- frequent heartburn or indigestion, ulcers
- difficulty urinating, kidney failure or kidney stones
- gall stones
- confusion, tremors, psychiatric illness
or if you:
- are pregnant, become pregnant, or are breast feeding your baby. Your doctor will tell you should be taking SALAGEN
- are taking, or begin taking, any other medicines, even medicines you buy without a prescription. Some medicines may interfere with each other in your body.
Some people find SALAGEN tablets affect their vision. Make sure you know how this medicine affects you before you do dangerous activities at night or in low light (example: drive a car or use machines).
Interactions with this medication
Check with your doctor before starting any new prescription or over-the-counter medicines, including natural/herbal remedies while on SALAGEN.
Drugs that may interact with SALAGEN include:
- vitamins, nutritional supplements, and herbal products
and medications used to treat:
- Myasthenia Gravis (e.g. ambenonium)
- Common cold or motion sickness (e.g. some antihistamines)
- Hypertension (e.g. beta blockers like propranolol and metoprolol)
- Irritable bowel disease
- Parkinson's disease
- Urinary problems
Other related products
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.