Pletal (Cilostazol)

(℞) Prescription Required - Cilostazol is the Generic Equivalent of Pletal

    Pletal (Cilostazol) Dosage and Side Effects

    PLETAL is used to treat intermittent claudication. Intermittent claudication is a condition characterized by narrowing of blood vessels in the legs, which causes leg pain that worsens with walking and improves when resting.

    Proper Use of this medication

    Try to take this medicine around the same time each day.

    Follow the directions on your prescription label carefully. Don't take more or less PLETAL than is prescribed by your doctor.

    PLETAL Overdose

    If you suspect an overdose, contact a poison control center or emergency room immediately.

    Missed Dose of PLETAL

    If you miss a dose of PLETAL, take it as soon as you remember.

    However, if it's almost time for your next dose, skip the missed dose and continue on your regular medication schedule.

    Don't double up on doses to make up for a missed one. Contact your physician if you miss more than one dose of PLETAL.

    Side Effects

    Common Side Effects of PLETAL

    Tell your doctor if any of the following side effects are severe or don't go away:

    • Diarrhea
    • Nausea
    • Stomach pain or gas
    • Heartburn or indigestion
    • Headache
    • Dizziness or lightheadedness
    • Increased frequency of coughing
    • Muscle pain

    Serious Side Effects of PLETAL

    Tell your doctor right away if you experience any of the following serious side effects:

    • Fast or irregular heartbeat
    • Unusual bruising or bleeding
    • Sudden, severe headache or vomiting
    • Vision changes
    • Unusual weight gain
    • Swelling of the hands, arms, feet, ankles, or lower legs
    • Dark, tarry, or bloody stools
    • Vomit that looks like coffee grounds
    • Signs of infection, which may include fever, sore throat, rash, or chills

    Warnings and Precautions

    PLETAL contains a black-box warning because similar medications have caused an increased risk of death in people with congestive heart failure.

    Tell your doctor if you have or have ever had any type of heart failure before taking this drug.

    Also, tell your doctor if you have or have ever had:

    • Bleeding problems or a disorder that causes an inability to form blood clots
    • Any active bleeding (especially a peptic ulcer or brain bleeding)
    • Low blood platelet levels
    • Liver disease
    • Kidney disease
    • Allergies to medications, foods, or other substances

    Tell your doctor or dentist you're taking this medication before any type of surgical procedure, and let your healthcare provider know if you've had a recent surgery before starting on PLETAL.

    In rare instances, this drug can lower your body's ability to fight infection. Avoid contact with people who have colds or infections.

    PLETAL should be used with extreme caution in children. Safety and effectiveness in kids hasn't been confirmed.

    Older adults may be more sensitive to the side effects of PLETAL.

    This medicine controls symptoms of intermittent claudication, but it doesn't cure the condition.

    Continue to take PLETAL even if you feel well. Don't stop taking the drug without first talking to your doctor.

    You might notice improvements within two to four weeks of starting on PLETAL, but it can take up to 12 weeks for you to experience the full benefits of the medicine.

    Be sure to keep all doctor and laboratory appointments while taking PLETAL.

    Pregnancy and PLETAL

    It's not known whether PLETAL is safe to take during pregnancy.

    Talk to your doctor before taking this medicine if you're pregnant or plan to become pregnant.

    It's also not known whether the medication passes into breast milk or could harm a breastfeeding baby.

    Don't breastfeed while taking PLETAL without first talking to your doctor.

    Interactions with this medication

    Tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking while taking PLETAL, especially:

    • Anticoagulants (blood thinners) such as Coumadin (warfarin)
    • Aspirin
    • Antifungal medications such as Diflucan (fluconazole), Sporanox (itraconazole), and Nizoral (ketoconazole)
    • Antiplatelet medications such as Plavix (clopidogrel), Effient (prasugrel), and Ticlid (ticlopidine)
    • Biaxin (clarithromycin)
    • Cardizem, Dilacor, or Tiazac (diltiazem)
    • E-mycin and Ery-Tab (erythromycin)
    • Luvox (fluvoxamine)
    • Prozac (fluoxetine)
    • Prilosec (omeprazole)
    • Serzone (nefazodone)
    • Zoloft (sertraline)

    PLETAL and Grapefruit

    Consuming grapefruit and grapefruit juice may affect how your body reacts to PLETAL.

    Talk to your doctor about this potential interaction.

    PLETAL and Other Interactions

    PLETAL may cause dizziness. Don't drive or operate machinery until you know how this medicine affects you.

    Try to avoid using sharp objects and participating in activities such as contact sports to lower your risk of getting cut, bruised, or injured while taking PLETAL.

    PLETAL and Alcohol

    Alcohol may worsen certain side effects of PLETAL.

    Talk to your doctor before consuming alcohol while taking this medication.

    Other related products

    The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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