Euflexxa (Hyaluronate Sodium)

(℞) Prescription Required

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Euflexxa 20mg/2mL

Product of United Kingdom
Manufactured by: Ferring Inc.
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Euflexxa 20mg/2mL
Product of United Kingdom
Manufactured by Ferring Inc.
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Euflexxa (Hyaluronate Sodium) Dosage and Side Effects

EUFLEXXA is similar to the fluid that surrounds the joints in your body. This fluid acts as a lubricant and shock absorber for the joints. EUFLEXXA is used to treat knee pain caused by osteoarthritis. EUFLEXXA is usually given after other arthritis medications have been tried without successful treatment of symptoms.

Proper Use of this medication

EUFLEXXA is injected directly into your knee joint. A healthcare provider will give you this injection.

EUFLEXXA is usually given once every week for 3 to 5 weeks. Follow your doctor's dosing instructions very carefully.

To prevent pain and swelling, your doctor may recommend resting your knee or applying ice for a short time after your injection.

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

Call your doctor for instructions if you miss an appointment for your EUFLEXXA injection.

Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • severe pain or swelling around the knee after the injection;
  • fast heart rate, sweating, chills or shaking; or
  • heavy feeling, anxiety, confusion.

Less serious side effects may include:

  • warmth, pain, stiffness, swelling, or puffiness where the medicine was injected;
  • nausea, stomach pain;
  • headache;
  • back pain;
  • numbness or tingly feeling;
  • cold symptoms such as stuffy nose, sneezing, sore throat;
  • tired feeling; or
  • itching or skin irritation around the knee.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Warnings and Precautions

You should not receive EUFLEXXA if you are allergic to it, or if you have an infection in your knee or in the skin around your knee.

Before you receive a EUFLEXXA injection, tell your doctor if you have blood clots or circulation problems in your legs, or an allergy to birds, feathers, or egg products.

For at least 48 hours after your injection, avoid jogging, strenuous activity, high-impact sports, or standing for longer than 1 hour at a time.

Call your doctor at once if you have severe pain or swelling around the knee after the injection.

You should not receive EUFLEXXA if you are allergic to it, or if you have an infection in your knee or in the skin around your knee.

To make sure you can safely receive EUFLEXXA, tell your doctor if you have:

  • blood clots or circulation problems in your legs; or
  • an allergy to birds, feathers, or egg products.

It is not known whether EUFLEXXA will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether EUFLEXXA passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Interactions with this medication

For at least 48 hours after your injection, avoid jogging, strenuous activity, or high-impact sports such as soccer or tennis. Also avoid weight-bearing activity or standing for longer than 1 hour at a time. Ask your doctor how long to wait before you resume these activities.

There may be other drugs that can interact with EUFLEXXA. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Other related products

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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