DDAVP (Desmopressin) Dosage and Side Effects
DDAVP Tablets reduce the amount of urine so a child's bladder will not fill up; therefore, a child will not wet the bed at night.
Proper Use of this medication
How many DDAVP Tablets should be used?
Take the medication at the dose prescribed by your physician 1 hour before bedtime. Use the following dosage plan or one that has been recommended by your physician.
Step 1: For the first 3 nights:
Take 1 tablet (1×0.2 mg) 1 hour before bedtime.
If the child is dry for 3 nights taking 1 tablet each night, continue this way. Do NOT increase the dose.
If the child is NOT dry for these 3 nights, move to Step 2.
Step 2: Nights 4, 5 and 6:
Take 2 tablets (2×0.2 mg) 1 hour before bedtime.
If the child is dry for 3 nights taking 2 tablets each night, continue this way. Do NOT increase the dose.
If the child is NOT dry for these 3 nights, move to Step 3.
Step 3: Nights 7, 8 and 9:
Take 3 tablets (3×0.2 mg) 1 hour before bedtime.
If the child is dry for 3 nights taking 3 tablets each night, continue this way. Do NOT increase the dose.
If your child is not dry every night after taking 3 tablets each night for 3 nights, see the “What should I do if ...?” section below or visit your doctor to find out why the medicine has not worked.
What should I do if ...?
The child is still wetting the bed:
Make sure the child is taking the correct number of tablets each night.
Limit the number of drinks the child has after supper.
If it's still not working, call your doctor.
As with all medicines, side effects may be experienced. With DDAVP Tablets, these may include headache, dizziness, rash, and mild abdominal cramps. These have occurred usually when the medication is being adjusted. Once you are taking the right amount of medicine for your condition, these side effects will usually go away. Tell your doctor about any side effects you experience.
Warnings and Precautions
Infrequently, high doses of DDAVP have produced transient headache and nausea. Nasal congestion, rhinitis, flushing and mild abdominal cramps have been reported. These symptoms disappeared with reduction in dosage. Please contact your physician should your child experience any side effects. For DDAVP to work at its best, it is very important to limit the number of drinks the child has after supper, especially 1 hour before bedtime. As most children sleep between 8 to 12 hours, further fluid restriction is not required. In the event the child wakes up during the night, liquid intake should be restricted.
Interactions with this medication
Tell your child's doctor or pharmacist in the unlikely event your child is taking any of the following medications (they are adult medications known to cause water retention and should be avoided when taking DDAVP); clofibrate, chlorpromazine, carbamazapine, tricyclic antidepressants (such as amitriptyline, nortriptyline), selective serotonin reuptake inhibitors (SSRIs for example, fluoxetine or Prozac, paroxetine or Paxil, sertraline or Zoloft, fluvoxamine or Luvox, citalopram or Celexa), nonsteroidal anti-inflammatory drugs (NSAIDs such as etodolac or Ultradol, ibuprofen or Advil or Motrin, naprosen or Naprosyn), celecoxib or Celebrex) and loperamide or Imodium.
Other related products
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.