Cyclomen (Danazol)

(℞) Prescription Required

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Cyclomen 50mg

Product of Canada
Manufactured by: Sanofi Aventis
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Danocrine is also marketed as Cyclomen
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Cyclomen 50mg
Product of Canada
Manufactured by Sanofi Aventis
Top Brand Choice
Top Generic Choice

Cyclomen 100mg

Product of Canada
Manufactured by: Sanofi Aventis
*Product image for reference use only.
Danocrine is also marketed as Cyclomen
Select Quantity
Cyclomen 100mg
Product of Canada
Manufactured by Sanofi Aventis
Top Brand Choice
Top Generic Choice

Cyclomen 200mg

Product of Canada
Manufactured by: Sanofi Aventis
*Product image for reference use only.
Danocrine is also marketed as Cyclomen
Select Quantity
Cyclomen 200mg
Product of Canada
Manufactured by Sanofi Aventis
Select your dosage

Cyclomen (Danazol) Medication Information

 

Uses

Cyclomen is used to treat:

  • Treatment of endometriosis 
  • Symptoms of fibrocystic breast disease associated with severe breast pain and tenderness

Dosage

The oral capsules are available in the following strengths:

  • 50 mg
  • 100 mg
  • 200 mg

Side Effects

The most common side effects of Cyclomen include:

  • Development of male characteristics
  • Headache
  • Change in vision
  • Loss of appetite
  • Nausea
  • Vomiting
  • Blood clot
  • Jaundice 

To obtain a full list of side effects that apply to you, contact your doctor or pharmacist

Precautions

Cyclomen can cause harm to an unborn baby when given to pregnant women.

The use of Cyclomen to treat endometriosis may increase the risk of cancer of the ovaries or may induce tumors of the liver.

Interactions

Common medications that interact with Cyclomen are listed:

  • Carbamazepine
  • Phenytoin
  • Cyclosporine
  • Tacrolimus
  • Anti-hypertensive
  • Insulin
  • Statins
  • Warfarin 

Contact your doctor or pharmacist to receive more information

Storage

Store at controlled room temperature (68-77ºF). Keep out of reach of children.

Pharmacist Tips

  • If you miss a dose of Cyclomen, you should take it as soon as possible, unless it is already time for your next dose. Then skip the missed dose and take the regularly scheduled dose to avoid double doses
  • If suspected of a drug overdose, even when no symptoms present, immediately contact your doctor, emergency department or regional Poison Control Center
  • If your symptoms return after finishing treatment with Cyclomen, talk to your doctor to discuss if you may be able to start the treatment again

Danazol FAQs

Should this be given with food?

Can be given with or without food

 

What is the length of treatment?

Recommended time for treatment is a maximum of three to six months

 

Should I use birth control while on this medication?

An effective non-hormonal method of contraception should be used during the complete course of therapy.

 

Can irregular periods occur with this medication?

Regular menstrual patterns, irregular menstrual patterns, and amenorrhea each occur in approximately one-third of patients treated with 100 mg of Cyclomen. However, these are observed more often with higher doses. 

 

What is the drug danazol used for?

Cyclomen is used to treat cyclic breast pain, as well as endometriosis. 

 

Is danazol a steroid?

Cyclomen is not a steroid. 

 

What is the mechanism of action of danazol?

Cyclomen suppresses the body’s release of follicle-stimulating hormone and luteinizing hormone, to decrease the rate of growth of abnormal breast tissue, and to reduce the amount of tissue in the uterus.

 

Does danazol increase testosterone?

Danazol increases the concentration and proportion of testosterone that is carried unbound in the blood. 

 

Related Drugs

  • Aygestin
  • Deblitane
  • Errin
  • Lyleq
  • Lyza
  • Norlyroc

Reference:

Cyclomen {package insert}. Laval, Quebec: Sanofi-Aventis Canada Inc.; 2017.

https://products.sanofi.ca/en/Cyclomen.pdf

PharmD Medical Writer

Author: Dr. Larisa Roybal, PharmD

Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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