Clobex Spray (Clobetasol Propionate)

(℞) Prescription Required

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Clobex Spray 0.05%

Product of Canada
Manufactured by: Galderma
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Clobex Spray 0.05%
Product of Canada
Manufactured by Galderma
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Clobex (Clobetasol Propionate) Dosage and Side Effects

CLOBEX is a topical medicine used to treat eczema, psoriasis, allergies (such as an allergic reaction to poison ivy), and many other skin conditions.

Warnings and Precautions

Before using CLOBEX, tell your doctor if you have, or have ever had:


•A skin infection

•Thinning of the skin

•Acne, perioral dermatitis, rosacea, or any other skin problems

•Cushing's syndrome (an adrenal gland disorder)

•A recent vaccination


•Tuberculosis (TB)

•Chickenpox or shingles

•Circulation problems

•Immune disorders

•Intracranial hypertension (increased pressure in the head)

•Glaucoma or cataracts (eye conditions)

•Allergies to medicines

Don't use CLOBEX for longer than two consecutive weeks (or four consecutive weeks for some formulations that are used on the scalp), unless your doctor tells you otherwise.

Let your doctor know if your symptoms don't improve, or if they worsen during your treatment with CLOBEX.

If you have diabetes, CLOBEX may raise your blood sugar levels. Be sure to monitor your condition carefully.

Using too much CLOBEX — or using this medicine for a long period of time — may increase your risk of developing adrenal gland problems.

Tell your doctor right away if you experience any of the following symptoms:

•Blurred vision

•Dizziness or fainting

•Fast or irregular heartbeat

•Irritability, depression, or anxiety

•Unusual tiredness or weakness

•Increased thirst or urination

•Unusual weight gain (especially in the face)

•New or worsening high blood pressure

•Loss of appetite or weight loss

•Muscle weakness

Steroids may affect growth in some children and teens. Talk to your doctor if this is a concern.

Don't use this medicine on a child under age 12 without consulting with a doctor.

Tell your healthcare provider you're using CLOBEX before having any type of medical or dental procedure.

Pregnancy and CLOBEX

It's not known whether CLOBEX could harm an unborn baby if used during pregnancy.

Tell your doctor if you're pregnant or might become pregnant.

It's also unknown whether this medicine passes into breast milk. Talk to your doctor before using CLOBEX while breastfeeding.

Side Effects

Common Side Effects of CLOBEX

Tell your doctor if any of the following side effects become severe or don't go away:

•Mild irritation



Serious Side Effects of CLOBEX

Tell your doctor right away if you experience any of the symptoms in the CLOBEX Warnings section above, or the following serious side effects:

•Severe burning, itching, or redness

•Skin thinning or discoloration

•Severe skin rash



•Nausea or vomiting

•Excessive hair growth

•Inflamed hair follicles

•Signs of an infection, which may include redness, swelling, or oozing of the skin

•Signs of anaphylaxis, which may include rash, hives, itching, difficulty breathing, tightness in the chest, or swelling of the face, mouth, lips, or tongue

Interactions with this medication

Tell your doctor about all prescription, nonprescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking, especially:

•Other steroids

•Other topical medicines

•Any drug that affects your immune system


Proper Use of this medication

CLOBEX comes as a cream, gel, ointment, or spray to apply to the skin.

It's also prescribed as a foam, lotion, or shampoo to use on the scalp.

This medicine is typically applied once or twice daily.

Your dose will depend on the formulation you're using and your medical condition.

Follow the instructions on your package label carefully. Don't use more or less CLOBEX than is recommended.

Clean the affected area before use. Then apply a thin layer of CLOBEX, and rub it in gently.

Wash your hands after applying this medicine, unless your hands are being treated.

Don't wrap or bandage treated areas of your skin unless your doctor tells you to do so. Follow your healthcare provider's instructions carefully if you need to apply a wrap or bandage.

The scalp lotion form of CLOBEX should be applied directly from the squeeze bottle.

Don't cover your scalp with a shower cap while it's being treated.

If you're using the shampoo, don't wet your hair first.

This medicine should be used only on the skin. Don't get CLOBEX in your eyes, mouth, nose, or vagina.

Don't apply CLOBEX to your face, underarms, or groin area unless your doctor tells you otherwise.

Some formulations of CLOBEX may not be suitable to use on a baby's diaper area.

If your healthcare provider has told you to use CLOBEX on your child's diaper area, avoid dressing your child in plastic pants or tight-fitting diapers.

Ask your doctor before using cosmetics or other skin products on areas of your body that are treated with CLOBEX.

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The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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