Clindoxyl Gel (Clindamycin/Benzoyl Peroxide)

(℞) Prescription Required

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Clindoxyl Gel 3%/1%

Product of Canada
Manufactured by: GlaxoSmithKline Inc.
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Clindoxyl Gel 3%/1%
Product of Canada
Manufactured by GlaxoSmithKline Inc.
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Clindoxyl Gel 5%/1%

Product of Canada
Manufactured by: GlaxoSmithKline Inc.
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**Med currently on back order**
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Clindoxyl Gel 5%/1%
Product of Canada
Manufactured by GlaxoSmithKline Inc.
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Benzoyl Peroxide/Clindamycin Phosphate Gel 5%/1%

Product of Canada
Manufactured by: Taro Pharmaceuticals Ltd.
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Benzoyl Peroxide/Clindamycin Phosphate Gel 5%/1%
Product of Canada
Manufactured by Taro Pharmaceuticals Ltd.
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Clindoxyl Gel 5%/1%

Product of Turkey
Manufactured by: Stiefel Laboratories
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Clindoxyl Gel 5%/1%
Product of Turkey
Manufactured by Stiefel Laboratories
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Clindoxyl Gel (Clindamycin/Benzoyl Peroxide) Dosage and Side Effects

CLINDOXYL Gel and CLINDOXYL ADV Gel are prescription medicines used on the skin to treat moderate acne. CLINDOXYL Gel and CLINDOXYL ADV Gel should not be used to treat cystic acne (severe acne with lumps under the skin (cysts)).

Proper Use of this medication

CLINDOXYL Gel and CLINDOXYL ADV Gel should only be applied to your skin.

For use in adults and adolescents (aged 12 years and over).

  • CLINDOXYL Gel or CLINDOXYL ADV Gel should be used for the entire treatment period as instructed by your doctor even if your acne symptoms begin improving after a few days. Stopping your treatment too soon may result in the return of your acne condition.

  • Do not expect to see immediate improvement of your acne, be patient and apply your medication as your doctor has directed.

Instructions for applying CLINDOXYL Gel or CLINDOXYL ADV Gel:

  • Before you apply CLINDOXYL Gel or CLINDOXYL ADV Gel, wash the affected skin gently with a mild, non-irritating cleanser, rinse with warm water, and pat dry. Do not wash your face more than 2 to 3 times a day. Washing your face too often or scrubbing it may make your acne worse.

  • Gently apply CLINDOXYL Gel or CLINDOXYL ADV Gel to lightly cover the entire affected area of your skin (face) with a thin layer, once daily. A pea-sized amount should be applied for each area of the face (e.g., forehead, chin, each cheek).

  • Wash your hands with soap and water after applying CLINDOXYL Gel or CLINDOXYL ADV Gel.

Remember: CLINDOXYL Gel or CLINDOXYL ADV Gel has been prescribed by your doctor for you alone; do not allow other people to use it, even if they have the same condition that you have, as it may not be suitable for them.

If you do accidentally swallow CLINDOXYL Gel or CLINDOXYL ADV Gel seek medical advice. You may get symptoms similar to when you take antibiotics by mouth (an upset stomach).

Side Effects

During the first weeks of using CLINDOXYL Gel or CLINDOXYL ADV Gel, you may notice some skin irritation such as rash (including redness, raised bumps), dryness, itching, peeling, skin sensitivity or burning. These symptoms will normally subside if treatment is temporarily interrupted and restarted after your symptoms have settled.

  • Other side effects that have been reports include skin tingling sensation, discolouration at the application site, sensitivity to sunlight, worsening of acne.

  • If you experience symptoms such as severe diarrhea (bloody or watery) with or without fever, abdominal pain, or tenderness, you may have Clostridium difficile colitis (bowel inflammation). If this occurs, stop using CLINDOXYL Gel or CLINDOXYL ADV Gel and contact your healthcare professional immediately.

Warnings and Precautions

CLINDOXYL Gel and CLINDOXYL ADV Gel are for external use only.

Avoid contact with hair, fabrics, carpeting or other materials, as benzoyl peroxide may cause bleaching. Keep CLINDOXYL Gel and CLINDOXYL ADV Gel away from your eyes, inside the nose, mouth, lips, other sensitive areas, all mucous membranes and any irritated areas of the skin, such as cuts, scrapes, sunburns or broken skin. If contact occurs, flush with copious amounts of cool tap water for at least 5 minutes. If discomfort persists, consult your doctor.

Take care when applying this product to the neck and other sensitive areas, since skin irritation is more likely to occur.

Take care not to apply too much. Applying too much CLINDOXYL Gel/CLINDOXYL ADV Gel or applying it more frequently will not help your spots clear up more quickly, and may cause skin irritation. If this does happen, use the gel less often, or stop using it for a few days and then start again.

Limit your time in sunlight. Avoid using tanning beds or sunlamps. If you have to be in sunlight, wear a wide brimmed hat or other protective clothing. Apply a sunscreen every morning and re-apply during the day as needed.

If you have sunburn, allow the sunburn to settle before using CLINDOXYL Gel or CLINDOXYL ADV Gel.

Do not use any other acne medications, or other topical medications, unless your doctor instructs you to do so as this can increase the risk of skin irritation. If severe irritation develops, discontinue use and seek medical advice.

If you have recently taken or used other clindamycin or erythromycin-containing medicines, there is an increased chance that CLINDOXYL Gel or CLINDOXYL ADV Gel will not work as well as it should.

A bacterial infection that affects your hair follicles (folliculitis) has been reported with the long term use of clindamycin, an active ingredient in CLINDOXYL Gel and CLINDOXYL ADV Gel. If inflammation around your hair follicles develops, discontinue use and seek medical advice.

BEFORE you use CLINDOXYL Gel or CLINDOXYL ADV Gel, talk to your doctor or pharmacist if you:

  • Have any allergies.

  • Have any other medical conditions.

  • Are pregnant or planning to become pregnant. If you are pregnant, or think you could be, or if you are planning to become pregnant, do not take CLINDOXYL Gel or CLINDOXYL ADV Gel without checking with your doctor. Your doctor will consider the benefit to you and the risk to your baby of taking CLINDOXYL Gel or CLINDOXYL ADV Gel while you're pregnant.

  • Are breast-feeding or plan to breast-feed. It is not known whether the ingredients of CLINDOXYL Gel or CLINDOXYL ADV Gel can pass into breast milk. If you are breast-feeding, you must check with your doctor before you use CLINDOXYL Gel or CLINDOXYL ADV Gel. Do not use CLINDOXYL Gel or CLINDOXYL ADV Gel on your chest if you are breast-feeding to ensure that the baby does not accidentally get CLINDOXYL Gel or CLINDOXYL ADV Gel in their mouth.

During the first weeks of treatment, you may experience peeling and reddening. These symptoms will normally subside if treatment is temporarily interrupted and restarted after your symptoms have settled. Ask your doctor if there is a moisturizer you can use if this occurs. If you experience excessive peeling, redness, tenderness, drying, itching or irritation, consult your doctor for advice. Stop treatment and see your doctor if skin irritation becomes severe (severe redness, dryness, itching, stinging or burning).

Interactions with this medication

Know the medicines you take. Keep a list of them and tell your doctor/pharmacist about all the medicines and skin products you use.

Tell your doctor especially if you are taking or using any of the following medicine(s):

  • Neuromuscular blocking agents (medicines used as muscle relaxants when you are given an anaesthetic)—as CLINDOXYL Gel and CLINDOXYL ADV Gel have been shown to increase their activity.

  • Erythromycin—as it should not be used at the same time as CLINDOXYL Gel or CLINDOXYL ADV Gel.

  • Medicines that are applied to the skin which contain tretinoin, isotretinoin or tazarotene—if you are using any of these medications together with CLINDOXYL Gel or CLINDOXYL ADV Gel, they should be applied at different times of the day (e.g., one in the morning and the other in the evening). This is because CLINDOXYL Gel and CLINDOXYL ADV Gel can reduce the effectiveness of tretinoin, isotretinoin or tazarotene if used at the same time.

  • Other topical acne medication—as that can cause dryness, peeling or irritation of your skin. Use of these medicines at the same time as CLINDOXYL Gel or CLINDOXYL ADV Gel may cause additional irritation. If severe irritation or dermatitis develops, stop taking drug and seek medical advice.

  • Topical sulphonamides such as dapsone or sulfacetamide—as applying CLINDOXYL Gel or CLINDOXYL ADV Gel and followed by a topical sulphonamide may cause a temporary change in the colour (yellow/orange) of your skin and facial hair. CLINDOXYL Gel and CLINDOXYL ADV Gel should not be used with products that contain sulphonamides.

Other related products

 
 

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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