Celestone Soluspan Injection (Betamethasone)

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Celestone Soluspan Injection 6mg/mL

Product of Canada
Manufactured by: Merck Sharp & Dohme
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Celestone Soluspan Injection 6mg/mL
Product of Canada
Manufactured by Merck Sharp & Dohme
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Celestone Soluspan Injection (Betamethasone) Medication Information

Uses

The intramuscular use of Celestone Soluspan Injectable Suspension is indicated as follows:

  • Allergic states
  • Dermatologic diseases
  • Endocrine disorders
  • Gastrointestinal diseases
  • Hematologic disorders
  • Neoplastic disease
  • Ophthalmic disease
  • Renal disease
  • Respiratory diseases
  • Rheumatic disorder

Dosage

The multidose vial contains 5 mL of injectable suspension with a strength of 6 mg per mL.

Side Effects

The most common side effects of Celestone include:

  • Bradycardia
  • Cardiac arrest
  • Acne
  • Rash
  • Cushingoid state
  • Hirsutism
  • CHF
  • Fluid retention
  • Nausea
  • Depression
  • Emotional instability
  • Insomnia 

Speak with your doctor or pharmacist for a full list of side effects that applies to you.

Precautions

The lowest possible dose of corticosteroid should be used to control the condition under treatment. When reduction in dosage is possible, the reduction should be gradual. 

Since complications of treatment with glucocorticoids are dependent on the size of the dose and the duration of treatment, a risk/benefit decision must be made in each individual case as to dose and duration of treatment and as to whether daily or intermittent therapy should be used.

Kaposi’s sarcoma has been reported to occur in patients receiving corticosteroid therapy, most often for chronic conditions. Discontinuation of corticosteroids may result in clinical improvement.

Interactions

Some of the common drug interactions with Celestone:

  • Amphotericin
  • Antibiotics
  • Cyclosporine
  • Digoxin
  • Estrogen
  • Ketoconazole
  • NSAIDs
  • Vaccines

Speak with your doctor or pharmacist for more information. 

Storage

Store at controlled room temperature (77ºF). 

Pharmacist Tips

  • Avoid exposure to chickenpox or measles. If you are exposed, medical advice should be sought without delay
  • Do not to discontinue the use of corticosteroids abruptly or without medical supervision.
  • Celestone Injectable Suspension is contraindicated in patients who are hypersensitive to any components of this product.

Celestone FAQs

What is the initial dosage?

The initial dosage of parenterally administered Celestone Injectable Suspension may vary from 0.25 to 9.0 mg per day depending on the specific disease entity being treated.

 

Can I take this if I am pregnant?

Corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Infants born to mothers who have received corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism.

 

Can I take this while breastfeeding?

Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. Caution should be exercised when corticosteroids are administered to a nursing woman.

 

Can I receive live vaccines with Celestone?

Vaccination Administration of live or live, attenuated vaccines is contraindicated in patients receiving immunosuppressive doses of corticosteroids.

 

Can I stop taking steroids without a taper?

Do not discontinue the use of corticosteroids abruptly or without medical supervision.

 

Can the dosage be increased?

Situations which may make dosage adjustments necessary are changes in clinical status secondary to remissions or exacerbations in the disease process, the patient’s individual drug responsiveness, and the effect of patient exposure to stressful situations not directly related to the disease entity under treatment. In this latter situation it may be necessary to increase the dosage of the corticosteroid for a period of time consistent with the patient’s condition.

 

Related Drugs

Reference:

Celestone Soluspan {package insert}. Kenilworth, NJ: Schering Corporation; 2007.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/014602s047lbl.pdf

PharmD Medical Writer

Author: Dr. Larisa Roybal, PharmD

Dr. Roybal is a board-certified pharmacotherapy specialist who has practiced in both ambulatory and acute care settings. Her pharmacy interests include oncology and general inpatient pharmacy.

The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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