Aloxi (Palonosetron Hydrochloride)
Aloxi (Palonosetron Hydrochloride) Product Information
Aloxi is a prescription medicine used for treating nausea and vomiting that occurs with cancer patients who are undergoing chemotherapy. This medicine can be administered prior to treatment or surgeries to prevent patients from becoming nauseous or vomiting afterwards.
It works by blocking the chemicals in the body that can trigger nausea and vomiting.
Also known as Palonosetron and is among the medicines known as 5-HT3 receptor antagonists. It is nausea and vomiting medication that is given to chemotherapy patients.
The main role is to reduce the effects of serotonin, a chemical that is naturally produced in the body. Serotonin is associated with nausea and vomiting.
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Aloxi is available in a 0.5mg capsule, or in a 250mcg/5mL vial. The vial would be suitable for patients who would be receiving a injection from their doctor or health care professional.
There is currently no generic available for this medication, and both options are brand. The capsule is manufactured by Purdue Pharma starting at $92.00 USD price, and the injection starts at $119.00 USD price, produced by Helsinn Birex Pharma.
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This medication is available in the form of an injection and a capsule. The injection dose is 0.25mg, and it is given directly into a vein (intravenously) over thirty seconds, which needs to be done thirty minutes prior to the anticancer (chemotherapy) medication.
Capsules are taken orally and a dose has 0.5mg. Each capsule should be taken an hour prior to going in for chemotherapy. It has a light beige color and is an opaque soft gelatin capsule.
If you are taking Aloxi in any form, it can be taken with or without a meal. There are a lot of things that can affect correct dosage you require, including your weight, health condition and the medications you are on.
If you know that you have an allergy to palonosetron or other less active ingredients, avoid using Aloxi. This will be one way of ensuring that you don’t suffer from its side effects.
It’s also necessary to know that not all people who take Aloxi develop side effects. Those who do tend to experience mild side effects that can be easily tolerated. These include:
The above mentioned side effects are well-tolerated and if you find that they are too much to bear, talk to your doctor.
Severe abdominal discomfort must be reported to the doctor too, as it is a severe side effect of Aloxi. Moreover, stop taking it as soon as you notice symptoms like severe allergic reactions affecting your skin, throat, tongue and/or face.
Has your doctor asked you to take Aloxi? If they want to put you on Aloxi to control your nausea and vomiting during chemotherapy, take the following precautions:
- Tell your doctor that you are suffering from a given disease or health condition
- If you have a case of known allergies, including a palonosetron allergy, let your GP know about it
- If you are taking non-prescribed or prescribed medicines, let your doctor know
- If you are a pregnant woman or wishes to get pregnant, inform your physician
- In case you are currently breastfeeding a baby, inform your GP to be sure that your baby’s breast milk will be safe
- Have you had an allergy to dolasetron, granisetron or ondansetron? If yes, avoid taking palonosetron
- If you have a heart problem, especially if you have an abnormal heart rhythm, don’t take Aloxi
The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.